Endocrine Abstracts

Objective: To evaluate the monitoritation systems acceptance: capillary glucose measurements and continuous glucose sensors (CGSM and GUARDIAN).Research design and methods: 15 diabetics patients were monitoritatied in two diferents periods of time. (Period 1: Guardian, 86 hours long. Period 2: CGSM 72 hours long). Later, they had to fill a satisfaction questionnaire concerning several aspects which were valued from 0–6.<table boarder="1" cellpad...

Introduction: Catecholamine-secreting tumours derived from the adrenal medulla and the nodes of the autonomic nervous system are known as pheochromocytomas or paragangliomas, respectively. Although their clinical manifestations are similar, their differentiation is important from an epidemiological and prognostic point of view and their possibility of being associated with genetic syndromes.Case report: We present a case of a 16 year old patient, with no...

Introduction: Silent corticotroph adenomas (SCA) represent a subtype of pituitary adenomas whose prevalence is 3% of pituitary adenomas. They are characterized by having a positive immunohistochemistry to corticotropin (ACTH) without clinical or biochemical data of hypercortisolism. The diagnosis is a challenge since they are considered as ANF, and it is with the pathology report after surgery when they are classified as SCA. They have more aggressive behavior and recur more t...

Decreased insulin action has been proposed as the common factor that is in the background of the different components of the metabolic syndrome. Insulin resistance is also associated with a chronic activation of the innate immune system. The innate immune system constitutes the first line of body’s defence and it is constituted by different barriers (epithelia, adipose tissue), and different blood and tissue components as macrophages, and neutrophils. Once activated, the ...

Advanced differentiated thyroid carcinoma (aDTC), herein defined as locally unresectable and/or metastatic, is one of the most common late-stage endocrine neoplasias. However, available data about its natural history are limited. ERUDIT is a multicenter, observational, retrospective study of patients diagnosed with aDTC in Spain and Portugal. The study describes its natural history from the initial diagnosis until the advanced stages, focusing on specific characteristics of th...

Aim: To study the prevalence of metabolic syndrome (MS) and its relation with ghrelin in old men.Material and methods: Prospective-population based study (2002–2005) in which 153 independently living men older than 70 y were included. Comorbidities, physical exam, BMI, blood pressure were recorded and blood sample taken for biochemical and hormonal determinations. Metabolic syndrome was defined using IDF criteria.Results: MS w...

Introduction: Adrenocortical carcinoma (ACC) is a very rare neoplasm with an incidence of about one case per million population. It is an agressive tumor (overall 5-year survival 16–38%) and complete resection is the only curative treatment.Description of methods: We report four cases of ACC. The clinical and biochemical features at diagnosis along with clinical course of the disease are discussed.Results: Four patients (three...

Background: High prevalence of hypovitaminosis D in diabetic patients has been reported and has been associated with microvascular complications and insulin treatment in type 2 diabetic patients.Methods: Observational study in 92 inhospital patients with different types of diabetes. We analyzed the relationship between serum 25-hydroxyvitamin D (25-OHD) concentration and the clinical features associated with diabetes.Results: Of 36...

Small fish are excellent experimental models to screen endocrine-disrupting compounds, but current fish-based assays to detect endocrine disruption have not been standardized yet, meaning that there is not consensus on endpoints and biomarkers to be measured. Moreover, exposure conditions may vary depending on the species used as the experimental model or the endocrine pathway evaluated. Another drawback is the fact that most methods to detect endocrine disruption rely on the ...

Introduction: The aim of our study was to determine the frequency of hypogonadism (H) in males with type 2 diabetes (T2D) and its relation with erectile dysfunction (ED) and obesity.Methods: We studied 107 diabetic males who came successively to an Endocrine consultation. The presence of H was determined by total testosterone (T) with an immunofluerescence method and free testosterone (fT) calculated with Vermeulen’s equation, defining H if T<2 ...