Endocrine Abstracts

Purpose: Type two diabetes mellitus (T2DM) is a chronic disease of debilitating complications. Good glycemic control could delay disease progression and microvascular complications. Nonetheless, some patients cannot maintain glycemic control.Patients and Methods: We recruited 340 T2DM patients on metformin therapy and categorized them according to their HbA1c levels into patients with good vs poor glycemic control. The levels of serum leptin were measure...

Polyglandular autoimmune syndromes (PAS) are rare group of diseases, which characterised by association of two or more autoimmune endocrine disorders in a single patient. Often PAS is combined with autoimmune damage of non-endocrine organs. Type 3 PAS includes combination of autoimmune thyroid disease and other autoimmune conditions. The adrenal cortex is not involved. This type of PAS typically affects middle aged women. The cause is still unclear. In this case study I descri...

Background: Insulin pumps are used in the management of type 1 diabetes in children at Macclesfield District General Hospital (MDGH). There has been no study previously conducted at MDGH to check the efficacy of the insulin pumps against non-pump methods such as multiple daily injections.Methods: Review on the number of admissions, type of admissions and insulin administration method were collected from the years 2012–2015. The types of admissions w...

Brief overview: The control of diabetes is a somewhat constant chase, with optimal control being the goal. Indeed, there are many methods marketed claiming to improve control. This is with neglect to the most basic of techniques, blood glucose monitoring. This is highly dependent on individual and parent motivation levels.Objective: The objective of this study is to answer the question, ‘Does the frequency of blood glucose monitoring affect the cont...

Introduction and objectives: Placental apoptosis plays important roles in both normal physiological and abnormal pathological placental development. Fetal growth is highly dependent on the placenta, thus any disruption in placental formation may lead to intrauterine growth restriction (IUGR). The rat placenta consists of a basal zone (BZ) and labyrinth zone (LZ). The BZ is the major site of placental hormone production and it goes under physiological apoptosis at the end of te...

Nutritional education and improvement of nutritional knowledge is an effective intervention that improves School children health. With consideration to few accurate and successful nutritional teaching programs directed at our schoolchildren in this research we evaluated the status of nutrition education system in primary school children and mothers’ point of view. The study was a qualitative study as a Focus Group Discussion (FGD). The research team consisted of a coordin...

Background: With the advent of new therapeutic modalities, the overall survival of neuroendocrine tumor (NET) patients has increased. However, the impact of the symptoms, treatments on the quality of life (QoL) of the patients, accessibility to health care, and financial toxicity are underreported in the literature. We have established a prospective NET biobank to capture the burden of the disease on patients’ daily life and the impact on their QoLM...

A Western dietary pattern, characterized by high consumption of red and processed meat, soft drinks, refined grains, fats and sweets, has frequently been associated with an increased disease risk. However, the distinct association between the nutritional habits and prediabetes has only been scarcely investigated in Western populations. The aim of this study is to underline the relationship and suggest the possible causality between the two. We conducted descriptive survey and ...

Background: Polycystic ovary syndrome (PCOS) is a highly prevalent disorder affecting 4%-20% of reproductive-aged women worldwide. Those affected by PCOS have a variety of clinical findings, which can affect their quality of life. Evidence suggests that polycystic ovarian syndrome and migraines are linked. However, the relationship between polycystic ovary syndrome and other types of headaches and their severity has not been studied.Objectives: The purpo...

Background and aims: We previously reported BMI heritability in the UAE to be 39.9%; indicating a high (60.1%) contribution of environmental factors to obesity. This study aims to determine and compare co-twin monozygotic (MZ) and dizygotic (DZ) BMI concordances.Materials and methods: 200 twin pairs were identified (ICLDC patient database) and split into two age groups (≤18 and >18 years old). Opposite gender twin sets were considered DZ. In same g...