Endocrine Abstracts

Introduction: Fasting during Ramadan very often requires a change in lifestyle for patients and adaptation is not easy in individuals with type 2 diabetes (T2D). Physical activity, sleep duration and sleep time are subject to change during Ramadan, due to changes in the number and times of meals.Study Objectives: This study aims to assess the physical activity and sleep patterns of T2DM patients during Ramadan.Material and Methods:...

Introduction: Liraglutide has shown several benefits in diabetic patients, both in terms of glycemic profile and metabolic control. The objective of our work is to show the effects of liraglutide on the metabolic profile of obese T2D patients.Materials and methods: This is a prospective study involving 31 obese T2D patients followed at the Department of Endocrinology and Metabolic Diseases CHU IBN ROCHD from January 2018 to December 2022. The data analys...

Introduction: Metabolic disorders caused by acromegaly are responsible for three times the morbidity of the general populationStudy objectives: To analyze the different metabolic complications in acromegalic patients.Materiel and methods: This is a retrospective study of 62 cases of acromegaly followed at the Department of Endocrinology and Metabolic Diseases CHU IBN ROCHD from January 2005 to December 2022. The data analysis was d...

Background: Malignant paragangliomas are rare. Predictors of malignant potential include high levels of normetadrenaline and/or dopamine, and the presence of a germline mutation in the succinate dehydrogenase B gene (SDHB). Prognosis is poor and treatment options are limited, with only short-term responses observed after 131I-MIBG therapy or chemotherapy.Aim: To report response to the oral tyrosine kinase inhibitor sunitinib.<p cl...

Background: Cabergoline-associated valvulopathy (CAV) is an established complication of cabergoline therapy in Parkinson’s disease, with a definitive echocardiographic triad of severe regurgitation, leaflet thickening, and restricted valve movement without calcification. Long-term cabergoline therapy is deemed safe for prolactinoma due to low dosage. We describe the first UK case report of aortic regurgitation (AR) associated with low-dose cabergoline in prolactinoma....

A Western dietary pattern, characterized by high consumption of red and processed meat, soft drinks, refined grains, fats and sweets, has frequently been associated with an increased disease risk. However, the distinct association between the nutritional habits and prediabetes has only been scarcely investigated in Western populations. The aim of this study is to underline the relationship and suggest the possible causality between the two. We conducted descriptive survey and ...

Background: Postoperative diabetes insipidus (DI) occurs predominantly following pituitary surgery. Here we present a case of transient DI developing after coronary artery bypass surgery (CABG) and aortic valve replacement and discuss the potential mechanisms.Case Presentation: A 69-year-old female with a past medical history of atrial fibrillation, hypertension and stroke was admitted for elective aortic valve replacement for severe aortic stenosis. The...

Background: The optimum management strategy for primary hyperparathyroidism remains debatable especially in patients with mild or asymptomatic disease. We aimed to compare the baseline characteristics and long-term outcomes of patients with primary hyperparathyroidism who were either managed conservatively or underwent elective parathyroidectomy.Methodology: We carried out a retrospective cohort analysis of patients with primary hyperparathyroidism under...

Introduction: Over 94% of total mortality in Georgia is attributable to non-communicable diseases (NCDs). Alhought various NCDs guidelines and protocols have been developed and approved in Georgia, their implementation at the primary healthcare (PHC) level has not been successful. The AIM of the study was to assess PHCs approaches to prevention and management of diabetes.Methods: General practitioners (GPs), family and village doctors were involved in a ...

Obesity is the modern medical problem. According to the WHO expert panel the prevalence of obese population worldwide is 300 million and overweight is 750 million.In the first trimester of 2007, we studied the obese patients in the Iv. Javakhishvili State Medical University’s Department of Endocrinology. The objective of our research was to study the course of subclinical hypothyroidism adjunct with severe obesity, its diagnostic criteria and treatm...