Endocrine Abstracts

In patients with polycystic ovary syndrome (PCOS) a high prevalence of autoimmune Hashimoto’s thyroiditis has been consistently observed. Young female patients present with menstrual and reproductive disorders as well as weight gain. The aim was to present a cohort of patients with PCOS who underwent thyroid function tests and in some of whom autoimmune Hashimoto’s thyroiditis was diagnosed. A cohort of 20 female patients aged 17-34 years is described. Patients prese...

Euthyroid sick syndrome also known as nonthyroidal illness syndrome is the reaction of the thyroid gland to severe disease. The SARS-CoV-2 virus affects the thyroid gland and may cause subacute thyroiditis, autoimmune Hashimoto’s thyroiditis, Graves’ disease, exacerbation of Graves’ disease and a form of silent thyroiditis. The aim was to study thyroid hormone levels and identify the presence of euthyroid sick syndrome in the context of severe SARS-CoV-2 disease...

Polycystic ovary syndrome (PCOS) is now globally recognised as the most common endocrinopathy in women of reproductive age and has a prevalence of 5-21% depending on the criteria used (NIH, Rotterdam or Androgen Excess Society). What is special about the syndrome is its dual entity involving both the reproductive and metabolic profile of the women affected. As a result, any intrinsic or extrinsic factors affecting both these components, could lead to pathophysiological alterat...

Background: Hormonal disturbances may be encountered in the context of paraneoplastic syndromes. Neuroendocrine tumors (NETs) represent a rare group of cancers, derived from the group of chromaffin cells, thus their paraneoplastic potentials remain relatively unexplored.Case presentation: Middle-aged female presented to the local A&E with psychosis, hyperglycemia, mild hypokalemia. Background includes resected ovarian cancer and chemotherapy before 3...

Obesity and DM2 increasingly affect young adults worldwide, to the point of warranting the description of ‘epidemic’. This means that greater numbers of women of reproductive age are at risk. Frequently DM2 remains undiagnosed until pregnancy. The rate of congenital malformations seems to be the same with that of women with DM1, but the rate of perinatal mortality appears to be increased, according to a recent meta-analysis. These findings occur despite the fact that...

Introduction: Thyroid storm is a rare condition, reflecting an extreme physiological state within the spectrum of thyrotoxicosis. The disorder consists of the clinical manifestations of thyrotoxicosis in association with altered mental status. On the other hand, excess circulating thyroid hormones are associated with glycemic disorders, like hyperglycemia and insulinopenia. Moreover, diabetic ketoacidosis has been associated with thyroid storm in few cases. We report the case ...

Introduction: Primary hyperparathyroidism is the most common cause of hypercalcemia in the ambulatory setting. Once the diagnosis has been confirmed, imaging of the parathyroid glands is performed locally with a combination of ultrasound scan (USS) and sestamibi/single-photon emission computed tomography (SPECT CT) to localise a parathyroid adenoma prior to surgery.Method: Data was collected on patients undergoing parathyroid surge...

Introduction and aim: Turner Syndrome (TS) is associated with a variety of morbidities affecting nearly every body system, and necessitates multidisciplinary management. To facilitate care, the International Turner Syndrome Consensus Group have drafted Clinical Practice Guidelines that were disseminated to ESE members in April 2017. The aim of this audit was to assess whether current management of adolescent and adult TS women in our care is in accordance wi...

Introduction: Primary hyperparathyroidism is the most common cause of hypercalcemia in the ambulatory setting. Once the diagnosis has been confirmed, imaging of the parathyroid glands is performed locally with a combination of ultrasound scan (USS) and sestamibi/single-photon emission computed tomography (SPECT CT) to localise a parathyroid adenoma prior to surgery.Method: Data was collected on patients undergoing parathyroid surge...

Introduction and aim: Turner Syndrome (TS) is associated with a variety of morbidities affecting nearly every body system, and necessitates multidisciplinary management. To facilitate care, the International Turner Syndrome Consensus Group have drafted Clinical Practice Guidelines that were disseminated to ESE members in April 2017. The aim of this audit was to assess whether current management of adolescent and adult TS women in our care is in accordance wi...