Endocrine Abstracts

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death. A 59-year old female, under treatment for depressive disorder, diagnosed with type 2 diabetes since 2016 and treated with glargine (20 IU/day), lispro (30 IU/day) insulin and Metformin (500 mg/day) was admitted to the Internal Medicine department via ER (emergency room) for repetiti...

Introduction: Diabetic autonomic neuropathy (DAN) and CAN as one of its most common manifestations are serious complication of type 1 and type 2 diabetes mellitus leading to a significant increase in morbidity and mortality. Case presentationA 51-year old male, diagnosed with T2DM for 25 years, complicated by stage III diabetic polyneuropathy, proliferative retinopathy and several amputations on both feet, treated with Metformin (2g/day), Glargine (26 IU/day) and Aspart (21 IU...

Objectives: To assess the prevalence of diabetic peripheral neuropathy (DPN) among futsal players participating in the 2017 edition of the European Futsal Championship for people with diabetes (DiaEuro).Methods: In this cross-sectional study were included 94 amateur/professional futsal player, from 9 European countries. The evaluation was made based on the data extracted from the standard medical certificate completed by each player’s diabetologist....

Polyglandular autoimmune syndromes (PAS) are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected. PAS type IV is a rare syndrome characterized by the association of autoimmune endocrine gland disorder which doesn’t fulfill the criteria of PAS type I-III. A 35-years old female diagnosed with alopecia areata and latent autoimmune diabetes of the adult (LADA) one year...

Cutaneous lymphoid hyperplasia (CLH) is a spectrum of benign conditions characterized by reactive B- and T-cell cutaneous lymphocytic infiltrates. The most common presentation of reactive CLH is as a solitary red skin papule, nodule, or plaque but 10–15% of patients present with more generalized or multifocal skin lesions. A 40-year old male, initially diagnosed with type 1 diabetes mellitus (DM), with a family history of autoimmune thyroid disease, vitiligo and type 2 DM...

Background: Resistance to thyroid hormone beta (RTHβ) is an inherited syndrome of reduced tissue responsiveness to thyroid hormones (THs). It is driven in 85% of cases by mutations in the thyroid hormone receptor beta (THRb). The estimated incidence is 1:40.000 to 1:19.000 live births. We report the clinical, laboratory, and genetic analysis of a patient with this disorder.Case report: A 12-year-old boy with a history of Attention-Deficit/H...

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death.A 76-years old female, with significant cardiac pathology, diagnosed with type 2 diabetes and treated with Humalog Mix50® 0-0-24 U/day, is admitted to our center via ER (emergency room) after an episode of severe hypoglycemia after administratio...

Upper extremity deep vein thrombosis (UEDVT) is not infrequent and accounts for approximately 14% of deep vein thrombosis. The risk of pulmonary embolism is lower than in lower extremity DVT and prompt diagnosis is essential to select those patients who deserve anticoagulant treatment. Previous studies indicated that type 2 diabetes (DM) patients carried greater risk of DVT development or recurrence than the general population.A 49-years old female, with...

Polyglandular autoimmune syndromes (PAS) are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected. In PAS III, autoimmune thyroiditis occurs with another organ-specific autoimmune disease, but the syndrome cannot be classified as PAS I or II.A 29-years old man was refer to our center for diagnostic confirmation with the following complaint...

Introduction: Type 1 diabetes mellitus (T1DM) is the most common form of diabetes in children and young adults. Though T1DM often presents in an acute manner, it may be preceded by a prodromal period, often extending over years.Case report: A 19-year-old male, diagnosed with T1DM at the age of 15, with no insulin treatment, was admitted to our department for high glycemic value (G) of 365 mg/dl on a routine exam at his GP. At diagnosis the patient was as...