Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep138 | Calcium and Bone | ECE2023

Clinical characteristics of sporadic and MEN1-associated primary hyperparathyroidism in young patients

Aboishava Lizaveta , Elfimova Alina , Gorbacheva Anna , Salimkhanov Rustam , Eremkina Anna , Karaseva Elena , Mokrysheva Natalia

Introduction: Primary hyperparathyroidism (PHPT) is commonly the most early manifestation of multiple endocrine neoplasia syndrome type 1 (MEN1), but it can also occur in young patients without any inherited disorders. The aim of our study was to compare the clinical characteristics of PHPT in young patients with MEN1 syndrome and with sporadic disease.Patients and Methods: The study included 72 patients with MEN-1 associated PHPT and 168 patients with s...

ea0090ep149 | Calcium and Bone | ECE2023

The daily calcium profile in patients with chronic hypoparathyroidism depending on different 25(OH) vitamin D level

Kovaleva Elena , Eremkina Anna , Elfimova Alina , Karaseva Elena , Gorbacheva Anna , Aboishava Lizaveta , Mokrysheva Natalia

Introduction: Chronic hypoparathyroidism is a rare disease, which usually treated with active forms of vitamin D and oral calcium. Supplementation with native vitamin D can be useful both for achieving "non-skeletal" effects of vitamin D and for a more stable serum calcium profile.Aim: The aim of this study was to estimate the daily serum calcium and 24-hour urine calcium levels in patients with chronic hypoparathyroidism depending on different 2...

ea0090ep172 | Calcium and Bone | ECE2023

Epidemiological characteristics of cardiovascular diseases in primary hyperparathyroidism according to the Russian Registry

Dobreva Ekaterina , Eremkina Anna , Gorbacheva Anna , Bibik Ekaterina , Kovaleva Elena , Gins Nikolay , Mokrysheva Natalia

Objective: Primary hyperparathyroidism (PHPT) is associated with a higher incidence of different cardiovascular diseases (CVD), but the prevalence of CVD in PHPT remains unclear.Aim: To evaluate the prevalence of CVD in PHPT according to the RussianPHPT Registry.Materials and Methods: The Registry includes a database of patients with PHPT available at the Endocrinology Research Centre (Moscow) since 2007, which was transferred to t...

ea0049ep1064 | Pituitary - Clinical | ECE2017

Low incidence of hyperprolactinemia following traumatic brain injury

Tortora Anna , La Sala Domenico , Tramontano Anna Luna , Bisogno Francesca , Angrisani Elisabetta , Carrano Mario , Vitale Mario

Background: Traumatic brain injury (TBI) is a major cause of disability and death, and a cause of neuroendocrine dysfunction. Partial or complete pituitary dysfunction is a frequent event occurring in 25–50% of subjects after a TBI as result from damage to either the pituitary or the hypothalamus. This large variability depends on the screening methods and on the difficulty to predict the effects of the trauma on pituitary. Growth hormone deficiency and gonadotropin defic...

ea0049ep1297 | Thyroid (non-cancer) | ECE2017

The assessment of influence vitamin D deficiency on the Hashimoto’s thyroiditis activity

Lizis-Kolus Katarzyna , Hubalewska-Dydejczyk Alicja , Sowa-Staszczak Anna , Skalniak Anna , Kowalska Aldona , Lizis Pawel

: The observed increase in the incidence of Hashimoto’s thyroiditis (HT) requires research on factors that may affect its development. One of them may be vitamin D deficiency which is an epidemiological problem all over the world.Aim: The assessment of influence vitamin D deficiency on the HT activity.Material and methods: 310 people were enrolled in the study: 155 patients with HT (a-TPO and/or a-TG positivity)-144 women (93%...

ea0041ep39 | Adrenal cortex (to include Cushing's) | ECE2016

The classical form of congenital adrenal hyperplasia-clinical characteristics and genetic analysis

Przybylik-Mazurek Elwira , Kurzynska Anna , Skalniak Anna , Piatkowski Jakub , Hubalewska-Dydejczyk Alicja

Classical form of congenital adrenal hyperplasia (CAH) is associated with the impairment of enzymes involved in process of adrenal steroidogenesis. More than 90% of CAH cases are connected with mutations in the 21-hydroxylase gene CYP21A2 in the HLA class III area on the short arm of chromosome 6p21.3. CAH is characterized by a strong correlation between the genotype and the phenotype. Mutations in the CYP21A2 gene can cause different degrees of loss of 21-hy...

ea0041ep1069 | Thyroid (non-cancer) | ECE2016

The efficacy of Radioiodine Therapy in Patients with Graves’ Disease

Dabrowska Anna , Kijek Jolanta , Tarach Jerzy , Torun-Jurkowska Anna , Chrapko Beata , Kurowska Maria

Introduction: Radioiodine (RAI) has been used for the treatment of Graves’ hyperthyroidism since 1940s. It is relatively safe and considered as one of the definitive therapies. Achievement of hypothyroidism or euthyroidism is defined as a successful therapy.Methods: The study was conducted in 366 patients (80.60% of women) with Graves’ disease (GD), aged 46.76±13.52 years. We analyzed retrospectively hormonal and imaging findings (scintigr...

ea0041ep1081 | Thyroid (non-cancer) | ECE2016

The efficacy of radioiodine therapy in patients with hyperfunctioning thyroid nodules

Dabrowska Anna , Kijek Jolanta , Tarach Jerzy , Torun-Jurkowska Anna , Chrapko Beata , Kurowska Maria

Introduction: Radioiodine (RAI) is used as a definitive therapy of hyperthyroidism due to toxic adenoma (TA) as well as toxic multinodular goiter (TMG). Achievement of hypothyroidism or euthyroidism is defined as a successful therapy.Methods: The study was conducted in 666 patients – 484 with TA and 182 with TMG (85.58% of women), aged 56.19±13.88 years. We analyzed retrospectively hormonal and imaging findings (scintigraphy, ultrasonography), ...

ea0041ep1156 | Thyroid cancer | ECE2016

A case of thyroid cancer followed by metachronous cancers and a pituitary tumour

Baldys-Waligorska Agata , Skalniak Anna , Piętkowski Jakub , Sowa-Staszczak Anna

Introduction: Based on cancer registries, the risk of second primary malignancies in patients with DTC increases by 30%. In our case report we aimed at understanding the patomechanism of metachronous primary tumours in patients with thyroid cancer.Case: In a 71-year old female surgery of nodular goitre (1988), followed by papillary thyroid cancer (pT3NxMx) surgery (2008) and complementary 131-I treatment (2009), were performed. In diagnostic WBS (2010) n...

ea0037ep926 | Thyroid (non-cancer) | ECE2015

Usefulness of Body Adiposity Index % in comparison to body composition analyser parameters among patients with and without autoimmune thyroid diseases hospitalised on Endocrinology Department-preliminary report

Koszowska Aneta , Nowak Justyna , Puzon Anna Bronczyk , Kupka Karolina Kulik , Dittfeld Anna , Szkodzinska Barbara Zubelewicz

Introduction: Anthropometric parameters such like BMI aren’t suitable enough for each type of figure and leads to misinformation about body composition. Body Adiposity Index (BAI) is suggested as an alternative for BMI.Aim: The aim of the study was to compare the usefulness of BAI in context to body composition parameters.Materials and methods: The BAI index was calculated for 86 patients according to previously described form...