Endocrine Abstracts

Introduction: Observed increasing frequencies of asymptomatic or oligosymptomatic PHP cases may increase the rate of false negative imaging results.Aim: To determine the level of PTH and calcium at which an enlarged parathyroid gland can be detected by parathyroid SPECT/CT.Material and methods: A retrospective analysis of 117 patients diagnosed with PHP (100 females and 17 males, aged 16–88 years) was performed. In each patien...

Introduction: Obesity is a risk factor for the development of insulin resistance, type 2 diabetes, cardiovascular diseases and non-alcoholic fatty liver disease. The aim of our study was to examine predictive value of liver enzymes in assessing biomarkers of insulin sensitivity in obese, non-diabetic adults.Methods: 1104 obese, non-diabetic adults were included in the study. Patients were divided into two groups: Group A (BMI 30.0–39.9 kg/m2</s...

The routine use of adjuvant RAI treatment in low-risk DTC remains controversial due to the lack of unequivocal evidences of its effectiveness in radically operated subjects. The aim of the study was a retrospective evaluation of long-term outcomes of combined DTC treatment to evaluate the impact of adjuvant RAI therapy in the low risk group. Primary hypothesis was: ‘if adjuvant RAI treatment was unnecessary, a delay in RAI administration would have no impact on long-term ...

Introduction: Women with polycystic ovary syndrome (PCOS) are at increased risk of developing insulin resistance and type 2 diabetes mellitus (T2DM). The aim of this study was to detect insulin resistance parameters that could be the best predictor T2DM in PCOS when compared with healthy women.Methods: This study include 114 PCOS women (BMI: 29.2±0.60 kg/m2; age: 25.3±0.57 years) and 41 controls (age- and BMI-matched) healthy women (...

Introduction: Metabolically obese normal weight (MONW) subjects, despite their normal BMI, present metabolic disturbances characteristic of abdominal obesity. One of the reasons might be subclinical inflammation caused by the fat tissue excess. The aim of the study was to asses the association between accumulation of fat (especially abdominal) and concentration of selected proinflammatory cytokines – interleukins (IL-6, IL-18) and C-reactive protein (CRP).<p class="ab...

Introduction: Reliable prognostic factors are crucial to choose the optimal treatment strategy and follow-up for differentiated thyroid carcinomas (DTC) patients. Thus, the aim of the study was a retrospective evaluation of prognostic factors of cancer relapse in patients treated in a single institution.Material: The study group consisted of 510 DTC patients, staged pT1b-T4N0-N1M0, treated with total thyroidectomy followed by complementary 131...

Introduction: It is well documented that adrenal tumor tissue is responsive to human chorionic gonadotropin (hCG) as well as to luteinizing hormone (LH) with both hormones sharing a similar physiological role and a mutual receptor.Objective: The objective of our study was to assess the adrenal steroid response to acute, exogenous hCG stimulation in patients with adrenal incidenatalomas (AI) and for the first time, in a healthy control group.<p class=...

Acromegaly is a rare disease, caused by an excessive secretion of growth hormone (GH), and consequently the insulin like growth factor 1 (IGF-1). Patients with acromegaly have an increased risk of fractures, which might be correlated with insufficient quality of bone. It is known that use of FRAX in acromegaly is not validated, however we do not have other useful tools to assess real risk for fractures. The new valuable tool in the assessment of bone structure is the trabecula...

Background: The partial or complete hypopituitarism is described as late complication of hemorrhagic fever with renal syndrome (HFRS). Imaging methods of pituitary gland examination in the chronic phase showed pituitary atrophy, but a precise pathogenic mechanism that causes pituitary damage in HRFS remains unclear. While hypopituitarism in HFRS is rarely described, cardiac failure as a known complication of hypopituitarism is even more rarely described. We present a case of s...

Introduction: Endocrine disorders and kidney diseases can coexist. Some of these have a common pathophysiological background. Strategies for treating endocrinopathy or glomerulonephritis (GN) may affect the function of the endocrine system and kidney.Aim: The study was aimed to assess the correlation of kidney biopsy results performed in people with suspected GN with thyroid function, metabolic syndrome and diabetes occurrence.Mate...