Endocrine Abstracts

Introduction: Endocrine Society guideline indications for screening (EGS) of hypertensive patients for hyperaldosteronism are not universally followed in clinical Endocrinology. We present a series of patients with hyperaldosteronism, diagnosed following strict EGS compliance.Methods: Retrospective. Following compliance with EGS in all patients attended in a general Endocrinology outpatient clinic, 70 hypertensive patients were diagnosed with hyperaldost...

Background: Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1-RA) whose role as a second-line treatment for patients with type 2 diabetes (T2D) has significantly increased. It has demonstrated cardiovascular safety and superiority in terms of glycaemic control and weight loss, compared to other GLP-1-RAs. The most common side effects are mild gastrointestinal, but it may also cause renal failure secondary to dehydration and an increased risk of diabetic retinopa...

Introduction: Data on sexual dysfunction (SD) in cirrhotic patients are limited. Sexual function is a complex area of human behavior with great impact on quality-of-life (QOL). Despite its relevance, it is rarely evaluated in clinical practice in cirrhotic patients. Indeed, published studies are heterogeneous, differ in the way sexual function is assessed, and usually evaluate only one specific aspect of sexual life. Our aim was to evaluate in detail the sexual function of pat...

Introduction: Controversy exists regarding type 2 diabetes (T2D) remission rates after bariatric surgery (BS) due to heterogeneity in its definition and patients’ baseline features. We evaluate T2D remission using recent criteria, according to preoperative characteristics and insulin use.Materials and methods: Retrospective study from a cohort of 657 BS performed in a single centre (2006–2011) of which 141 (57.4% women) had T2D. Evaluation of a...

Introduction: Remission of type 2 diabetes (T2D) is a yearned outcome after bariatric surgery (BS). Attention to individuals who do not strictly fulfil remission criteria has been frequently left behind. The aim of this study was to evaluate metabolic control status in patients considered as diabetes ‘non-remitters’.Materials and methods: Retrospective study of 125 patients (59.2% women) with preoperative diagnosis of T2D who underwent BS in a ...

The management of nonfunctioning adrenal masses is controversial. The size is usually the only criterion for surgical treatment. The objective was to study the progression of the tumor size and the follow-up of several cardiovascular risk parameters in patients with nonsurgical nonfunctioning adrenal masses.Retrospective longitudinal observational study of 24 patients (54.2% men) with nonfunctioning adenomas followed for five years without surgical treat...

Introduction: The increasing incidence of type 1 diabetes (T1D) is a matter of concern because it negatively impacts both the quality of life and its duration, due to the great morbidity and mortality caused by its chronic complications.Objective: To evaluate clinical care provided to Brazilian youths with T1D in daily practice, according to the American Diabetes Association’s guidelines.Methods: This was a cross-sectional, mu...

Introduction and objective: Neuroendocrine tumors (NETs) are relatively rare tumors. The majority are located in the gastrointestinal (GI) tract and bronchopulmonary system. The aim of this report is to study the characteristics of gastrointestinal NETs at diagnosis.Material and methods: Descriptive study about 18 patients diagnosed of gastrointestinal NETs during 1993–2011 in our hospital. Data regarding demographic, clinical, analytical, anatomopa...

Introduction and objective: Neuroendocrine tumors (NETs) are a rare kind of tumor that can have various locations. Pancreatic location is the most common after the gastrointestinal tract. The aim of this report is to study the characteristics of neuroendocrine tumors located in the pancreatic gland (pNETs) at diagnosis.Material and methods: Descriptive and retrospective study about 22 patients diagnosed of pNET during the period 1993–2010 in our hos...

Introduction: It has been previously described that prolactinomas may have a more aggressive behaviour in men than in women.Methods: We performed a retrospective study in 59 patients diagnosed of prolactinoma (19 men). The variables collected were: age at diagnosis, clinical presentation, tumor size and stage (Hardy classification) and treatment response. The results were compared between both genders.Results: Age at diagnosis was ...