Searchable abstracts of presentations at key conferences in endocrinology

ea0025p243 | Pituitary | SFEBES2011

Pituitary apoplexy is a rare endocrine emergency, historically confused with other acute medical conditions, which delayed the diagnosis, however with advances in brain imaging, diagnosing this condition is much easier

Jayashekara Acharya , Flanagan Daniel

We describe seven patients with pituitary apoplexy diagnosed between July 2009 and Oct 2010.Presentation and Management: Five patients presented with sudden onset headache, nausea and vomiting. One developed headache while on carbegoline and other presented with fluctuating level of consciousness.All but two patients were inpatients at the hospital when diagnosed and all had MRI scan of pituitary to confirm the diagnosis and any ma...

ea0021p330 | Steroids | SFEBES2009

Cyclical epilepsy associated with testosterone replacement

Jayashekara Acharya , Flanagan Daniel

Introduction: High testosterone level lowers the seizure threshold in patients previously well controlled on medication.Clinical scenario: A 59-year-old male, with a history of complex partial seizure, having 12 years of seizure free period on phenytoin and lamotrigine, presented with short history of vomiting, positional headache, and visual impairment. A diagnosis of pitutary macro adenoma was made following a MRI scan of his head. He underwent a trans...

ea0021p193 | Endocrine tumours and neoplasia | SFEBES2009

Two cases of meningitis as a complication of pituitary adenoma

Tan Horng Kai , Jayashekara Acharya , Flanagan Daniel

Introduction: Meningitis is a recognized complication of the treatment of pituitary adenoma. It is usually considered as a peri-operative problem but does need to be considered as a potential complication at other points in the treatment pathway. We present two patients with meningitis where the link to pituitary pathology was originally unrecognized.Case report:Patient 2: 41 years old lady, presented with a history of nasal drip u...

ea0037ep1347 | Clinical Cases–Thyroid/Other | ECE2015

Gastrinoma with liver metastasis; is it always a bad news?

Akavarapu Sriranganath , Acharya Jayashekara , Valsalakumari Parvathy , Todd Jeannie

Introduction: Gastrinoma is a rare neuroendocrine tumor and associated with liver metastasis in 20–40% of cases. We present a rare case report of a patient with stable liver metastasis due to gastrinoma for more than 35 years.Case report: A 49 year old male is currently on our regular clinic follow up for the liver metastasis due to gastrinoma. His past history includes open laparotomy and resection of gastrinoma (Proven histologically) at the age o...

ea0073aep439 | General Endocrinology | ECE2021

A case report of cerebral salt wasting incorrectly diagnosed as the syndrome of inappropriate antidiuretic hormone secretion

Qayum Mohammed , Banwaith Tavlene , Nawaz Ghulam , Acharya Jayashekara , Sudarshan Veena

Cerebral salt wasting (CSW) occurs as the result of injury to the central nervous system and is most commonly found among those who have experienced a traumatic brain injury (TBI). Although incidence is varied, it has been reported to be as high as 30% within the patient population presenting to hospital with a TBI. CSW causes hyponatremia with concurrent hypovolemia and increased sodium within urine despite normal renal function. Because of its rare nature, CSW is often misdi...

ea0037ep55 | Adrenal cortex | ECE2015

Rare case of ectopic ACTH secreting tumour causing cyclical Cushing's syndrome

Acharya Jayashekara , Akavarapu Sriranganath , Abbara Ali , Parvathy Valsalakumari , Todd J F

We are reporting a rare case of ectopic ACTH secreting tumour causing cyclical Cushing’s syndrome. A 63-year-old lady presented in March 2013 with tiredness and bilateral leg swelling and weakness associated with easy bruising. She was admitted to local hospital in April 2013 with worsening proximal myopathy and peripheral oedema. Her midnight cortisol was elevated at 1710 nmol/l. ACTH 610 mU/l, prolactin 476 mU/l, GH 0.21 IU/l, TSH 0.73 mU/l, free T4 of 11.0 p...

ea0090p57 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

A Quality Improvement initiative to assess differences of diabetic ketoacidosis (DKA) management across hospitals in the United Kingdom

Dalzell Joseph , Skaria Maria , Kauser-Malik Saima , Raghavan Rajeev , Soghal Shamanth , Tabasum Maria , Ahmed Nabeel , Nizza Jael , Acharya Jayashekara , Saraf Sanjay , Dekode Team

Background: Joint British Diabetes Societies (JBDS) have developed guidelines for the treatment and management of diabetic ketoacidosis (DKA) in adults in the United Kingdom (UK). Multiple single center audits are known to assess compliance to guidelines. However, unified data on DKA management across multiple centers is unknown.Aims: To study the precipitating factors and assess for differences in DKA management across UK hospitals.<p class="abstext...