Endocrine Abstracts

Introduction: Diabetes is increasing its prevalence as an enhancement of treatment options arises and mortality declines. Pancreas transplantation has been postulated as one of them, specifically indicated for cases with end-stage renal failure where kidney transplantation is required besides. It has been analysed whether there is a clinical benefit in terms of quality of life (QoL) in patients undergoing pancreas-kidney transplantation (PKT) compared to dyalisis population or...

Clinical case: A 51 year-old caucasian woman was admitted in the emergency room of our hospital with psicomotor agitation and confusion after four days of a profuse watery diarrhea, with 5 stools per day, abdominal cramps and vomiting. She started 500 mg of aspirin on her own initiative. Her medical profile included a type 2 diabetes treated with metformin 850 mg/12 hours and glyburide 7.5 mg/day, and hypertension treated with enalapril 20 mg/day. No renal imparement was docum...

RationaleObesity is associated with multiple comorbidities including nonalcoholic steatohepatitis (NASH). Despite its association with increased morbidity and mortality, treatment options are limited. Some studies have suggested that glucagon-like peptide-1 receptor agonists (aGLP-1) are associated with NASH resolution. Additionally, the effects of bariatric surgery on NASH-associated liver fibrosis are controversial.Methods<p ...

BackgroundPatients with neuroendocrine neoplasms (NENs) might present with malnutrition due to the tumor itself and/or its treatment. Poor nutritional status and weight loss can lead to poor outcomes, including decreased quality of life, increased complication rates and mortality. Ghrelin is an orexigenic hormone, which is implicated in appetite regulation, body weight, inflammation and immune cell activation. Its gastric secretion mainly depends on the ...

The newly created NIFTP category (non-invasive follicular thyroid neoplasm with papillary-like nuclear features) has had a notorious impact in the management of thyroid neoplasms. Its incidence appears to be higher in western countries than Asiatic, but there are few studies including more than one institution.Objectives: To evaluate retrospectively the incidence of NITFP in a multicentre study in two adjacent countries as well as to compare th...