Endocrine Abstracts

Introduction: Fasting during Ramadan is an obligatory practice for adult Muslims. Although exemptions exist in certain conditions,including diabetes, the majority of diabetic patients fast despite this concession with the risk of complications mainly hypoglycemic accidents. The aim of this study is to establish the relationship between hypoglycemic accidents and drug treatment, therapeutic education, clinical and biological characteristics of tunisian diabetic patients during ...

Background: Familial chylomicronemia is a rare disorder of lipoprotein metabolism characterized by severe fasting hypertriglyceridemia. We present here a case of severe familial chylomicronemia with multiple complications.Case presentation: A 35-year-old Tunisian woman was suffering from chylomicronemia (Fredrickson type I hyperlipoproteinemia) since the age of 10 years old. Her dyslipidemia was caused by a lipoprotein lipase deficiency. Since her childh...

Introduction: Treatment adherence is fundamental in diabetes control. The aim of our study is to evaluate treatment adherence in patients with type 2 diabetes and to determine its associated factors.Methods: Cross-sectional study enrolling 80 type 2 diabetes patients followed up in the outpatient department of the national institute of nutrition. The Morisky questionnaire was used to evaluate treatment adherence. Age, gender, body mass index (BMI), diabe...

Introduction: Over the past two decades, the development of genetic engineering techniques has led to the emergence of insulin analogue that have the advantage of improving diabetics quality of life compared to human insulin. The aim of our study was to compare the frequency of occurrence of degenerative complications in two groups of patients with type 2 diabetes (T2D) on human insulin (NPH) and analogue insulin, and thus determine whether or not there are benefits to prescri...

Introduction: Fasting during Ramadan is an obligatory practice for adultMuslims. Although exemptions exist in certain conditions, including diabetes, the majority ofdiabetic patients fast despite this concession with the risk of complications mainly hypoglycemic accidents.The aim of this study is to establish the relationship between hypoglycemic accidents and drug treatment, therapeutic education, clinical and biological characteristics oftunisian diabe...

Introduction: Ramadan fasting is one of the sacred rites in Islam. Diabetes patients are spared this obligation. However, mostof them insists on fasting.The aim of this study is to assess the clinical and metabolic impact of Ramadan fasting in Tunisia patients with diabetes during Ramadan 2019.Materials and methods: Prospective descriptivestudy carried out during Ramadan 2019 including 86 diabetic patients followed at the Nati...

Introduction: Insulin therapy ( IT) in type 2 diabetes( T2D) is an integral Pharmacologic Approache because of the progressive nature of the disease. Insulin improves glycemic control and reduces the risk of microvascular complications. It’s however associated with weight gain as a side effect which promotes insulinoresistance and cardiovascular morbi–mortality.In this work we evaluated long–term weight gain in insulin–treated pat...

Introduction: Primary biliary cirrhosis and autoimmune hepatitis are two chronic liver diseases. An overlap of the characteristic signs of these two conditions, determining an ‘Overlap syndrome’ can be seen. Type 1 diabetes can be associated with this syndrome due to the autoimmune predisposition.Observation: We report the case of a young type 1 diabetic patient referred to our service for additional management of a glycemic imbalance. This i...

Introduction: Diabetes is the leading cause of end-stage renal disease in Europe (12 to 30%). In the United States, it is the cause of more than half of the cases of this disease. Renal disease is a cardiovascular morbidity and mortality preacher which is three times more common in diabetic patients with diabetic nephropathy (DN). The aim of our study was to describe the factors of cardiovascular risk associated with ND in a group of type 2 diabetes (T2D) Tunisians.<p clas...

Introduction: Diabetic pregnancy is a high risk pregnancy. The objective of our study was to study the clinical-biological profile of pregnant women with gestational diabetes.Methods: It was a retrospective study of 82 pregnant diabetic women admitted to the day hospital of the National Nutrition Institute in Tunis for the management of gestational diabetes. All patients received regular follow-up until delivery.Results: The averag...