Searchable abstracts of presentations at key conferences in endocrinology

ea0020p244 | Bone/Calcium | ECE2009

Effect of one year treatment with strontium ranelate on bone mineral density in women with established osteoporosis previously treated with teriparatide

Anastasilakis Athanasios , Polyzos Stergios , Avramidis Avraam , Papatheodorou Athanasios , Terpos Evagellos

Teriparatide (TPTD – recombinant human parathyroid hormone 1–34) markedly increases bone mineral density (BMD) and reduces fracture risk. Sequential treatment with an antiresorptive agent is believed to preserve or further increase BMD. Strontium ranelate (SR) is thought to uncouple bone remodeling resulting in increased BMD and reduced fracture risk. In this prospective study, we aimed to evaluate the effect of SR on BMD in women with established osteoporosis previo...

ea0041ep108 | Bone & Osteoporosis | ECE2016

Serum leptin, adiponectin and ghrelin concentrations in post-menopausal women: is there an association with bone mineral density?

Mpalaris Vasilios , Anagnostis Panagiotis , Anastasilakis Athanasios , Goulis Dimitrios , Doumas Argyrios , Iakovou Ioannis

Introduction: Adipokines and ghrelin exert well-documented effects on energy expenditure and glucose metabolism. Experimental data also support a role in bone metabolism, although data from clinical studies are conflicting. The purpose of this cross-sectional study was to investigate the association of serum concentrations of leptin, adiponectin and ghrelin with bone mineral density (BMD) in post-menopausal women.Methods/design: BMD in lumbar spine and f...

ea0032p370 | Diabetes | ECE2013

Serum vaspin levels in women with and without gestational diabetes mellitus during pregnancy and postpartum

Gkiomisi Athina , Makedou Kali , Anastasilakis Athanasios , Polyzos Stergios , Kourtis Anargyros , Gerou Spyridon , Gavana Elpida , Dagklis Themistoklis , Rousso David , Giannoulis Charalambos

Although vaspin is regarded an insulin-sensitizing adipokine, its role in gestational diabetes mellitus (GDM) is currently unknown. We aimed to evaluate serum vaspin levels and their correlation with insulin resistance in women with and without GDM. Forty-four women with GDM (GDM Group 20 managed with diet only (GDM-diet) and 24 with diet plus insulin (GDM-insulin)) and 44 age-matched pregnant women with normal glucose tolerance (control group) were studied. Serum glucose, lip...

ea0070aep160 | Bone and Calcium | ECE2020

Serum and tissue expression profile of microRNAs that regulate genes related to the pathogenesis of sporadic parathyroid adenomas

Yavropoulou Maria , Pazaitou-Panayiotou Kalliopi , Makras Polyzois , Anastasilakis Athanasios , Poulios Chris , Daskalaki Emily , Chrysafi Sofia , Vamvakidis Kyriakos , Vlachodimitropoulos Dimitris , Yovos John

Background: Epigenetic changes appear to be implicated in the development of parathyroid tumors. In this study we investigated the microRNA expression profile in the serum and tissue samples from patients with primary hyperparathyroidism (PHP) due to sporadic parathyroid adenomas (SPAs).Methods: Our study cohort consisted of 40 patients with PHP due to SPAs that underwent parathyroidectomy (PTX).MicroRNA extraction was performed fr...

ea0022p77 | Bone/Calcium | ECE2010

The effect of zoledronic acid on serum homocysteine, folate and vitamin B12 in patients with Paget's disease of bone

Polyzos Stergios , Anastasilakis Athanasios , Efstathiadou Zoe , Litsas Ioannis , Kita Marina , Panagiotou Athanasios , Papatheodorou Athanasios , Arsos Georgios , Moralidis Efstratios , Barmpalios Georgios , Zafeiriadou Efthimia , Terpos Evangelos

Purpose: High serum homocysteine (HCY) and indirectly deficiency of folate and/or vitamin B12 stimulate bone resorption and adversely affect collagen cross-linking. The aim of this study was the evaluation of serum levels of HCY, folate and vitamin B12 in patients with Paget’s disease of bone (PDB) and the effect of zoledronic acid (ZOL) on their serum levels.Methods: This was a prospective open-label cohort study, with a control arm at baseline. Ni...