Searchable abstracts of presentations at key conferences in endocrinology

ea0090p562 | Adrenal and Cardiovascular Endocrinology | ECE2023

The Relationship Between Autonomic Cortisol Secretion and Metabolic Diseases in Cases with Adrenal Incidentaloma

Turan Erdogan Beril , Evranos Ogmen Berna , Sacikara Muhammed , Aydin Cevdet , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

Backgorund: Adrenal incidentalomas (AI) are lesions discovered incidentally on imaging without clinical symptoms or examination findings. AI can produce hormones in 5-30% of cases. Autonomic cortisol secretion (ACS) is the most common of these. Although ACS is asymptomatic, it increases the risk of metabolic disorders.Methods: Patients aged ≥18 years with adrenal adenoma and upper abdominal MRI who presented and were examined in the endocrinology o...

ea0049ep1152 | Female Reproduction | ECE2017

Does radioactive ıodine therapy affect fertility?

Evranos Ogmen Berna , Faki Sevgul , Burcak Polat Sefika , Bestepe Nagihan , Ersoy Reyhan , Cakir Bekir

Introduction: Thyroid carcinoma is common in young women. Radioactive iodine (RAI) therapy has been confirmed as a useful treatment in the management of differentiated thyroid carcinoma (DTC). For women with DTC, the effect of RAI therapy on gonadal and reproductive function is an important consideration. We aimed to evaluate effects of RAI therapy on ovarian function.Method: Women younger than 40 years old and diagnosed with thyroid cancer that required...

ea0041ep1114 | Thyroid cancer | ECE2016

Markers predicting the contralateral lobe involvement in patients with multifocal papillary thyroid carcinoma: An instutional case series of 914 patients

Polat Sefika Burcak , Cakir Bekir , Ogmen Berna , Baser Husniye , Cuhaci Neslihan , Aydin Cevdet , Ersoy Reyhan

Background: The characteristics of multifocal PTC remain controversial. Surgical approach to multifocal tumor changes between centers. In cases that the initial procedure was lobectomy, most clinicians would suggest for completion thyroidectomy since the risk of PTC in the contralateral lobe is significant. This study aimed to evaluate the incidence of bilateral involvement, predictive factors for bilaterality and whether or not bilaterality was related with more aggressive hi...

ea0041ep1148 | Thyroid cancer | ECE2016

Preoperative predictors of malignancy in lesions classified as BETHESDA IV

Polat Sefika Burcak , Ogmen Berna , Baser Husniye , Sungu Nuran , Dumlu Gurkan , Ersoy Reyhan , Cakir Bekir

Background: Differential diagnosis of a thyroid nodule is difficult if it is a follicular lesion. Follicular lesions include follicular adenoma (FA) or a malign neoplasm (follicular cancer (FC) or follicular variant of papillary thyroid carcinoma (FVPTC)). Cytology can’t separate benign from malignant condition in follicular lesions. Differential diagnosis is important because patients often undergo less than ideal interventions, such as a total thyroidectomy for a benign...

ea0037ep771 | Pituitary: clinical | ECE2015

Association of hormonal changes with disease severity and mortality rate in critically ill patients

Cuhaci Neslihan , Ogmen Berna , Doger Cihan , Polat Burcak , Izdes Seval , Ersoy Reyhan , Cakir Bekir

Introduction: Endocrinological and metabolic changes can occur in critically ill patients, which may affect the prognosis and outcome. The hypothalamic–anterior–pituitary axis (HPA) plays a crucial role in the endocrine regulation of metabolic and immunological homeostasis. In this prospective study, we evaluated the pituitary–adrenal–gonadal–thyroid axis in the adult Intensive Care Unit (ICU) patients,their outcome, the association between these hormo...

ea0037ep1228 | Clinical Cases–Pituitary/Adrenal | ECE2015

Successful systemic treatment of Xanthoma disseminatum with cyclophospamide: an interesting case with endocrine and gastrointestinal involvement

Ersoy Reyhan , Polat Sefika Burcak , Ercan Karabekir , Ogmen Berna , Ustun Huseyin , Ersoy Osman , Cakir Bekir

Introduction: Xantoma disseminatum (XD) is a rare non-Langerhans cell histiocytosis (NLCH) which is often resistant to treatment. In this report, we presented a case with extensive cutaneous, hypothalamohypophysial, cerebral and gastrointestinal system involvement, which responded well to cyclophosphamide.Case: A 16-year-old female patient admitted to our hospital with the complaints of amenorrhoea, weight gain, polidipsia, poliuria, yellow-brownish papu...

ea0035p147 | Calcium and Vitamin D metabolism | ECE2014

Hypoparathyroidism and celiac disease a rare autoimmune disease combination

Ogmen Berna , Cuhaci Neslihan , Polat Burcak , Aydin Cevdet , Ersoy Reyhan , Cakir Bekir

Case: A 30-year-old man with hypoparathyroidism has been treated with calcitriol and calcium for 2 years, admitted hospital with persisting diarrhea. An endoscopic operation is planned. But when he was waiting for this examination as outpatient condition, he had a convulsion and had been taken in hospital by parents. Initial laboratory analyses revealed that he was hypocalcemic (total calcium of 6 mg/dl) and parathormone (PTH) 8 pg/ml, phosphorus 5.7 mg/dl, and magnesium 2 mg/...

ea0035p894 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

‘High dose hook effect' in a patient with invasive giant prolactinoma

Ogmen Berna , Aydin Cevdet , Polat Burcak , Cuhaci Neslihan , Altundal Naci , Ersoy Reyhan , Cakir Bekir

Background: Prolactin secreting pituitary adenomas (prolactinomas) is the most common pituitary adenoma. The magnitude of prolactin secretion in prolactinomas is usually proportionate to the tumor’s size. Invasive giant prolactinoma is a large prolactinoma (>4 cm in dimension) presenting with serum prolactin levels of >1000 ng/ml and mass related clinical symptoms. Giant prolactinoma is rare and usually presents in men.Case report: A 52-year...

ea0035p916 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Lanreotide-induced bradycardia and supraventricular extrasystoles

Ogmen Berna , Polat Burcak , Cuhaci Neslihan , Aydin Cevdet , Ersoy Reyhan , Cakir Bekir

Case: A 63-year-old acromegalic woman admitted hospital for lassitude and dizziness. She has been diagnosed acromegaly 10 years ago and had two transsphenoidal operations. Remission wasn’t achieved. Then she started to use lanreotide (somatostatin analogue) and for 7 years she has been treated with it. In laboratory examination, basal plasma GH 1.21 ng/ml (NR:0–5); nadir GH level after glucose tolerance test, 1.2 ng/ml (NR: less than 1); IGF1, 129.1 ng/ml (NR: for ag...

ea0070aep138 | Bone and Calcium | ECE2020

A new and valuable predictor for the diagnosis of primary hyperparathyroidism: Ca/P Ratio

Bestepe Nagihan , cuhaci Neslihan , Polat Burcak , Ogmen Berna , Ersoy Reyhan , Cakir Bekir

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder that is characterized by hypercalcemia and elevated or normal levels of parathyroid hormone (PTH). Most PHPT cases are incidentally discovered when routine laboratory analysis reveals hypercalcemia. PHPT should be considered in any person with elevated serum calcium (Ca) levels and no clear evidence of malignancy. Serum phosphorus (P) is low due to the phosphaturic effects of PTH and mostly in the ...