Endocrine Abstracts

The aim: To evaluate effectiveness of complex therapy in patients with comorbidity of type 2 diabetes (DM2) and essential hypertension (EH) depending on genetic polymorphism peroxisome proliferator-activating receptor-γ2 (PPARγ2). Before and after 3 months of treatment we examined 145 patients with EH stage II, grade and DM2 moderate, subcompensated aged 45–60 years: group 1 (71 patients) received standart therapy (telmisartan, indapamide, metformin, gliclazide,...

Purpose: To study the features the structural and functional state of the myocardium and blood vessels in patients with diabetes mellitus and arterial hypertension depending on omentin level.Methods: A total of 65 patients (32 men and 33 women, mean age 51.6±5.2 years); 31- with type 2 diabetes and hypertension (group 1), 34 – with isolated arterial hypertension (group 2). Control group 20 healthy volunteers. We evaluated data transthoracic ech...

The purpose: To investigate the prevalence and the relationship between cardiovascular complications (CVC) and risk factors (RF) in patients with essential hypertension (EH) and coronary heart disease (CHD) in combination with diabetes mellitus type 2 (DM-2).Materials and methods: A retrospective analysis of case histories of 79 patients with cardiac profile (37 of them women, with an average patient age – 59.6±6.2 years) with hypertension stag...

The aim: To establish unfavorable genetic polymorphisms on the development of comorbidity of DM2 and EH in Ukrainian population and to evaluate the effectiveness of α-lipoic acid appointment (α-LC) in complex therapy in patients with 3-4 crossed unfavorable genetic polymorphisms.The primary examination of 167 patients with DM2 in combination with EH showed that A/C and C/C genotypes of AGTR1, Pro/Pro genotype of PPARγ2, Arg/Arg ...