Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep191 | Calcium and Bone | ECE2023

Severe calcific uremic arteriolopathy lessions and acute hypocalcemia after parathyroidectomy for secondary hyperparathyroidism in haemodialysis patients: Case series

Hristov Ioana , Elena Aciobanitei , Radu Danila

Introduction: Calcific Uremic Arteriolopathy (CUA) is a rare but severe complication of end-stage kidney disease with one year survival rates between 45-55%. Extensive skin ulcers and concomitant painful purpura are the clinical features and diagnosis criteria as defined by Hayashi. Parathyroidectomy treatment for hyperparatiroidism is reserved for patients with inadequate response to calcimimetics, persistent elevated PTH>800 pg/ml or calciphylaxis and it has been shown t...

ea0037ep244 | Calcium and Vitamin D metabolism | ECE2015

Quick PTH improves the cure rate of minimally invasive surgery in patients with primary hyperparathyroidism and preoperative localized parathyroid adenoma

Velicescu Cristian , Gatu Alina , Danila Radu , Grigorovici Alexandru , Mogos Voichita

Introduction: Intraoperative quick PTH (iqPTH) monitoring is important in the treatment of primary hyperparathyroidism (pHPTH), allowing, together with preoperative localisation, the switch from routine bilateral neck exploration to limited gland excision.Aims: We checked the advantage of iqPTH for improving the cure rate of patients operated for pHPTH by using minimally invasive surgery (MIS).Materials and methods: Retrospective s...

ea0037ep1269 | Clinical Cases–Thyroid/Other | ECE2015

The association between Graves' disease and thyroid cancer: coincidence or causality? Case report

Bilha Stefana , Repede Ionut , Gatu Alina , Danila Radu , Velicescu Cristian , Mogos Voichita , Branisteanu Dumitru D

Introduction: Graves’ disease (GD) has been related to a higher incidence of thyroid cancer. Thyroid nodules found in GD seem to have a higher risk for malignancy. The prognosis of thyroid cancer may be aggravated by the association with GD.Case report: We present the case of N.I, a 56-year-old woman diagnosed with multinodular goitre and overt hyperthyroidism for which therapy with carbimazole 40 mg/day was started. She was referred to our Endocrin...

ea0070ep490 | Thyroid | ECE2020

Solitary fibrous tumour of the thyroid, features of a very rare tumour: A case report

Dumitru Teodora , Hrisa Anamaria , Nechita Mirela-Claudia , Ciobanu Delia , Danila Radu , Ungureanu Maria-Christina

Introduction: Solitary fibrous tumor (SFT) is a sporadic tumor, commonly found in the pleural cavity. It is like a large well-circumscribed mass, arising from mesenchymal tissue, with spindle cells proliferation, arranged in various patterns. SFT of the thyroid is exceptionally rare, with only about 28 cases being reported in the international literaterature.A 34-year-old woman presented in the Department of Endocrinology with the diagnosis of a multinod...

ea0090ep1136 | Late Breaking | ECE2023

Parathyroid carcinoma - case report

Teodoriu Laura , Siriteanu Andreea , Iancu Dragos , Bugean Gema , Danila Radu , Velicescu Cristian , Andriescu Elena-Corina , Ciobanu Delia , Stefanescu Cipriana

Parathyroid carcinoma (PC) is a rare endocrine tumor accounting for 0.5–6% or less in cases of primary hyperparathyroidism. According to The American Joint Committee on Cancer (AJCC) eighth edition, the histopathological criteria for PC include the presence of vascular invasion with capsular invasion and progression and/or metastasis to adjacent tissues. However, the small number of cases of PC makes it difficult to predict prognosis in the postoperative period of PC. We ...

ea0063p490 | Calcium and Bone 2 | ECE2019

Hyperparathyroidism – jaw tumor syndrome – differential diagnostic traps

Nechita Mirela Claudia , Tudurean-Olteanu Anca Georgiana , Costan Victor Vlad , Danila Radu , Preda Cristina , Ungureanu Maria Christina

Introduction: Hyperparathyroidism-Jaw Tumor (HPT-JT) syndrome is a rare genetic disorder bearing a germline and a somatic CDC73 mutation. The features of HPT-JT are clinically difficult to ascertain because the parathyroid disease, ossifying fibroma in the jaw and other abnormalities, often occurs asynchronously and may be diagnosed and treated separately. The association of jaw ossifying fibroma with primary hyperparathyroidism (PHPT) is typical of HPT-JT.<p class="abstex...

ea0041ep337 | Clinical case reports - Thyroid/Others | ECE2016

Management dilemma in papillary carcinoma arising from struma ovarii

Hreniuc Ana , Gherasim Simona , Preda Cristina , Ungureanu Maria-Christina , Vulpoi Carmen , Mogos Voichita , Piciu Doina , Danila Radu , Leustean Letitia

A rare ovarian teratoma consisting mainly of thyroid tissue, Struma ovarii accounts for up to 3% of all ovarian tumors. The thyroid tissue may demonstrate the same spectrum of pathological features as in the normal thyroid including benign and malignant changes.A 46-year-old woman was referred to our clinic in July 2015 by the oncologist, with the diagnosis of struma ovarii with carcinomatous transformation (follicular variant of papillary carcinoma).</p...

ea0037ep1312 | Clinical Cases–Thyroid/Other | ECE2015

A rare association: primary hyperparathyroidism and thyroid papillary carcinoma: case report

Zmau George-Sebastian , Preda Cristina , Stefanescu Cipriana , Danila Radu , Ciobanu Delia , Crumpei Iulia , Belceanu Alina Daniela , Manolachie Adina , Vulpoi Carmen

Introduction: Although, the relationship between pathological process of the parathyroid and thyroid is common, concurrence of primary hyperparathyroidism (pHPT) and papillary thyroid carcinoma (PTC) is extremely rare, probably because, unlike with medullary thyroid cancer, they have not a common embryologic origin. We present a case with this uncommon association.Case report: A 67-year-old woman with multinodular goitre was addressed in endocrinology fo...

ea0056p269 | Clinical case reports - Thyroid/Others | ECE2018

Concomitant primary hyperparathyroidism with papillary thyroid carcinoma: The role of dual-phase 99mTc-MIBI parathyroid imaging: case report

Anghel Adina , Vasiliu Gabriela , Ungureanu Maria Christina , Preda Cristina , Mogos Voichita , Stefanescu Cipriana , Danila Radu , Leustean Letitia

Introduction: Although concomitant primary hyperparathyroidism (PHPT) and papillary thyroid carcinoma (PTC) has been repeatedly reported in medical literature with an incidence of 2.3–4.3%, no causal relationship has been elucidated. In most cases, diagnosis of PTC is mostly incidentally, while PHPT is usually the primary pathology. Recent literature supports the possible role of dual-phase 99mTc-MIBI parathyroid imaging in detecting PTC in patients with PHPT.<...

ea0056p1164 | Thyroid cancer | ECE2018

The prevalence of concomitent non-medullary thyroid carcinoma and primary hyperparathyroidism

Teodoriu Laura , Balaceanu Raluca , Ungureanu Maria-Christina , Leustean Letitia , Grigorovici Alexandru , Danila Radu , Ciobanu Gabriela-Delia , Stefanescu Cipriana , Preda Cristina

Introduction: Synchronous medullary thyroid cancer and pHPT is common in MEN-2A (Sipple syndrome). In contrast, concomitant nonmedullary thyroid cancer and primary hyperparathyroidism (PHPT) is very rare even if the pathological relationship between parathyroid and thyroid diseases is common.Aim: Was to determine the prevalence of non-medullary thyroid carcinoma in patient who underwent neck exploration for PHPT.Patients and method...