Endocrine Abstracts

Introduction: Intraoperative quick PTH (iqPTH) monitoring is important in the treatment of primary hyperparathyroidism (pHPTH), allowing, together with preoperative localisation, the switch from routine bilateral neck exploration to limited gland excision.Aims: We checked the advantage of iqPTH for improving the cure rate of patients operated for pHPTH by using minimally invasive surgery (MIS).Materials and methods: Retrospective s...

Introduction: Graves’ disease (GD) has been related to a higher incidence of thyroid cancer. Thyroid nodules found in GD seem to have a higher risk for malignancy. The prognosis of thyroid cancer may be aggravated by the association with GD.Case report: We present the case of N.I, a 56-year-old woman diagnosed with multinodular goitre and overt hyperthyroidism for which therapy with carbimazole 40 mg/day was started. She was referred to our Endocrin...

Introduction: Solitary fibrous tumor (SFT) is a sporadic tumor, commonly found in the pleural cavity. It is like a large well-circumscribed mass, arising from mesenchymal tissue, with spindle cells proliferation, arranged in various patterns. SFT of the thyroid is exceptionally rare, with only about 28 cases being reported in the international literaterature.A 34-year-old woman presented in the Department of Endocrinology with the diagnosis of a multinod...

Introduction: Hyperparathyroidism-Jaw Tumor (HPT-JT) syndrome is a rare genetic disorder bearing a germline and a somatic CDC73 mutation. The features of HPT-JT are clinically difficult to ascertain because the parathyroid disease, ossifying fibroma in the jaw and other abnormalities, often occurs asynchronously and may be diagnosed and treated separately. The association of jaw ossifying fibroma with primary hyperparathyroidism (PHPT) is typical of HPT-JT.<p class="abstex...

A rare ovarian teratoma consisting mainly of thyroid tissue, Struma ovarii accounts for up to 3% of all ovarian tumors. The thyroid tissue may demonstrate the same spectrum of pathological features as in the normal thyroid including benign and malignant changes.A 46-year-old woman was referred to our clinic in July 2015 by the oncologist, with the diagnosis of struma ovarii with carcinomatous transformation (follicular variant of papillary carcinoma).</p...

Introduction: Although, the relationship between pathological process of the parathyroid and thyroid is common, concurrence of primary hyperparathyroidism (pHPT) and papillary thyroid carcinoma (PTC) is extremely rare, probably because, unlike with medullary thyroid cancer, they have not a common embryologic origin. We present a case with this uncommon association.Case report: A 67-year-old woman with multinodular goitre was addressed in endocrinology fo...

Introduction: Although concomitant primary hyperparathyroidism (PHPT) and papillary thyroid carcinoma (PTC) has been repeatedly reported in medical literature with an incidence of 2.3–4.3%, no causal relationship has been elucidated. In most cases, diagnosis of PTC is mostly incidentally, while PHPT is usually the primary pathology. Recent literature supports the possible role of dual-phase 99mTc-MIBI parathyroid imaging in detecting PTC in patients with PHPT.<...

Introduction: Synchronous medullary thyroid cancer and pHPT is common in MEN-2A (Sipple syndrome). In contrast, concomitant nonmedullary thyroid cancer and primary hyperparathyroidism (PHPT) is very rare even if the pathological relationship between parathyroid and thyroid diseases is common.Aim: Was to determine the prevalence of non-medullary thyroid carcinoma in patient who underwent neck exploration for PHPT.Patients and method...

Introduction: Metastatic disease into the thyroid is a rare event, despite the gland’s rich vascular supply. Renal cell carcinoma (RCC) is an unusual neoplasm that not only has the potential to recur after a latent disease-free interval, but also has the potential to metastasize to rare sites like the thyroid. However, of the clinically significant secondary neoplasms of the thyroid, metastatic RCC is the culprit in most cases. Case report: We prese...

Aims: We wanted to evaluate the correlations between the volume of the surgically removed parathyroid adenoma and the presurgical metabolic profile of patients diagnosed with primary hyperparathyroidism.Materials and methods: Prospective multicentric study, enrolling 52 patients with primary hyperparathyroidism from two medical units, proposed for surgery. Serum calcium and PTH were evaluated in all patients before surgery, and 25OH-D3 was measured only ...