Endocrine Abstracts

Introduction and aim: Primary hyperparathyroidism is the commonest cause of hypercalcaemia in out patient population. Primary hyperparathyroidism has become relatively common over the recent years as calcium levels are routinely evaluated since the introduction of multichannel analysers worldwide. Our aim was to audit the use and role of preoperative imaging (Ultrasound and Sestamibi scan) in localising parathyroid adenoma.Methods: We reviewed case notes...

Background and aim: Low testosterone levels are known to be associated with unfavorable body composition and testosterone replacement is known to be associated with increased muscle mass and muscle strength. The aim of this cross-sectionalstudy is to evaluate the grip strength, appendicular muscle mass and physical performance and bone mineral densities of hypogonad male patients.Method: 75 hypogonad and 45 healthy control subjects were included in this ...

Introduction: T1DM is caused by immune mediated destruction of pancreatic β-cells, leading to partial, or absolute insulin deficiency.The most frequent age of onset is 12 years. IGF-1 is a polypeptide with 70 amino acids and its chemical structure is similar to insulin. IGF-1 is associated with early development and has anabolic effect in adults. IGF-1 regulates many physiological functions, including glucose metabolism, cell survival and proliferation.<p class="abste...

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women in reproductive age. A condition that causes irregular menstrual periods because monthly ovulation is interrupted and levels of androgens are elevated. It occurs in about 5–10% of women and is considered to be the most common cause of anovulatory infertility in reproductive age.Objectives: To compare the prevalence, levels of thyroid auto-antibodies in a group ...

Aim: Progesterone is thought to be associated with hyperemesis gravidarum (HG). Pregnancies in which progesterone is administered for luteal phase support do not exhibit an increased incidence of HG, suggesting that high progesterone levels alone do not cause HG. The aim of the present study was to evaluate the therapeutic role of progesterone therapy as a new modality in the management of hyperemesis.Subjects: In total, 40 Egyptian women below 40 years ...

A 77 year old man developed a severe progressive polyneuropathy associated with significant disability. He was also found to have type 2 diabetes mellitus and antibody-negative primary hypothyroidism and was treated with gliclazide and thyroxine to good effect. Nerve conduction studies showed a demyelinating type neuropathy that was not typical of diabetic neuropathy. Two years later he was admitted with an episode of severe hypoglycaemia accompanied by low blood pressure, hyp...

Introduction: The novel severe-acute-respiratory-syndrome-coronavirus-2 virus has led to the ongoing Coronavirus disease 2019 (COVID-19) disease pandemic. There are increasing reports of extra pulmonary clinical features of COVID-19, either as initial presentations or sequelae of disease ((gastrointestinal, hepatobiliary, pancreatic, cardiovascular, ocular, and neurologic) Autoimmune/inflammatory syndrome induced by adjuvants (ASIA syndrome) can be seen as a post-vaccination p...

Objective: Assess the effect of bariatric surgery on serum glucagon like peptide-1 (GLP-1) concentration and metabolic and biochemical parameters pre and postoperatively.Methods: This prospective study comprised 50 subjects divided into 3 groups. Group 1: 20 obese subjects with T2DM (BMI >35) that underwent Roux-en-y gastric bypass surgery; Group 2: 20 lean subjects with T2DM and Group 3: 10 lean subjects as healthy controls.Bo...

Although Diabetic ketoalkalosis (DKAlk) has beendescribed as a mixed acid-base disorder over half a century ago, there is unawareness among physicians. Here, we present two cases to emphasize DKAlk which is more common than it’s thought.Case-1: A thirty-year-old female patient with type-1 diabetes and ten weeks of pregnancy presented with several weeks of vomiting. She also reported that she had hyperthyroidism for 2 weeks and that she used propylt...