Endocrine Abstracts

Introduction: Adrenocortical carcicnoma (ACC) is a rare malignancy with overall incidence of 0.7–2.0 cases/million. It’s a rare & aggressive childhood cancer with a reported incidence of 0.2– 0.3 new cases per 1 million. It has Bimodal distribution - at first decade - 85% functional & 5-6th decade of life 15-30% functional. Paediatric virilising adrenal tumours have a better prognosis after complete resection than in adults. Surgery is the mai...

Background: Etiology of hypopituitarism differs in tropical countries compared to the West and includes pituitary abscess, snake bite, HIV infection, Sheehan syndrome, road traffic accidents, iron overload states etc.Aims and Objectives: The present case series highlights the spectrum of hypopituitarism in tropical countries.Case Details: 1. C1: 23 y/o female presented with loss of consciousness, unrecordable BP and hypoglycemia. H...

Introduction: Ectopic PTH secretion is rare, to our knowledge, with only 27 cases reported in the literature and 3, ( a tonsil, a lung and a penile) due to squamous cell carcinoma .In the few cases reported to date it appears to be more common in males and in those over the age of 60. The management of the hypercalcemia in this setting is complicated. We are aware of 2 other case reports in which cinacalcet was used in this context, but as in our case, unsuccessfully.<p cl...

Introduction: Acromegaly is an insidious disease caused by chronic GH and IGF-I hypersecretion associated with increased morbidity and mortality, mostly from cardiovascular complications. The aim of this study is to compare cardiovascular risk factors, between patients with medical treatment vs cured.Materials and methods: This is a retrospective study of 37 acromegalic patients, 21 well controlled with medical treatment (IGF-I within the normal range fo...

IntroductionThe term collision tumor refers to the coexistence of two histologically distinct malignant neoplasms. The two malignancies can originate from the same organ or occur as metastases from other regions. This type of tumors involving the thyroid gland are especially rare. Reported cases are usually involving papillary thyroid carcinomas in coexistence with other types of tumors like medullary carcinoma, follicular carcinoma or metastasic disease...

IntroductionMalignant insulinoma is a rare pancreatic neuroendocrine tumor that accounts for only 10% of all cases of insulinoma. The clinical picture is characterized by the presence of severe hyperinsulinemic hypoglycaemic syndrome in a patient with pancreatic tumor with locoregional and/or distant metastases. Therapeutic management is challenging due to the need to control both hypoglycemic syndrome and tumor growth. Curative surgery is rarely applica...