Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep153 | Calcium and Bone | ECE2022

The parathyroid carcinoma manifesting during pregnancy

Sazonova Daria , Bibik Ekaterina , Gorbacheva Anna , Eremkina Anna , Mokrysheva Natalia

Background: Parathyroid carcinoma (PC) is a rare cause of primary hyperparathyroidism (PHPT) and extremely rare endocrine malignancy during pregnancy. Different maternal and fetal/neonatal complications of PHPT occur in 67 and 80% of untreated cases respectively, probably more due to severe hypercalcemia.The diagnostic and therapeutic approaches are limited in pregnant women and require individual risk-benefit assessment.Aim: We present a case of PC mani...

ea0063gp21 | Calcium and Bone 1 | ECE2019

The long-term outcomes of chronic post-surgical hypoparathyroidism

Mokrysheva Natalia , Eremkina Anna , Kovaleva Elena

Hypoparathyroidism (HP) is a rare disease characterized by an absence or inappropriately low concentrations of circulating parathyroid hormone, leading to hypocalcaemia, hypophosphatemia and elevated urinary calcium excretion.Aim: To determine complications in chronic post-surgical HP patients.Material and methods: We have analyzed the data from 76 patients (71 women and 5 men; median age 51.8 years (range 18–77)) with chronic...

ea0073ep30 | Calcium and Bone | ECE2021

Sporadic multiple parathyroid gland disease in young woman with primary hyperparathyroidism

Bibik Ekaterina , Eremkina Anna , Mokrysheva Natalya

BackgroundMost cases of primary hyperparathyroidism (PHPT) is caused by a single benign adenoma, multiple parathyroid neoplasms (MPN) occur less often in 10–15%, parathyroid carcinoma accounts for <3%. MPN can be sporadic or develop due to inherited genetic syndromes (most commonly multiple endocrine neoplasia syndrome type 1 (MEN-1) that usually manifest at a young age. The preoperative examination of patients with MPN is important for achievin...

ea0081ep132 | Calcium and Bone | ECE2022

Association of preoperative therapy by native form vitamin D and hypocalcemia after parathyroidectomy in primary hyperparathyroidism patients

Elfimova Alina , Eremkina Anna , Rebrova Olga , Kovaleva Elena , Mokrysheva Natalia

Background: Primary hyperparathyroidism (PHPT) is a common endocrine disorder resulting from oversecretion of parathyroid hormone (PTH) in parathyroid glands. Hypocalcemia can occur in the postoperative period after parathyroidectomy (PTE) and can be challenging to control and requires varying doses of supplementation. Vitamin D deficiency can worsen the severity of PHPT and promote the development of “hungry bone syndrome” due to increased influx of calcium into bon...

ea0081ep139 | Calcium and Bone | ECE2022

«Physician to physician» telemedicine consultations in parathyroid pathology: experience of quaternary endocrinological medical center

Gorbacheva Anna , Fadeyeva Maria , Eremkina Anna , Mokrysheva Natalia

Introducton: Telemedicine consultations (TMC) are a useful tool for ensuring communication between medical specialists, especially in a large country and in the era of COVID-19. It is important to study the needs and possibilities of TMC for various diseases, in particular, for the pathology of the parathyroid glands.Materials and methods: TMC between regional health specialists and Endocrinology Research Centre (Moscow, Russian Federation) were conducte...

ea0081ep146 | Calcium and Bone | ECE2022

Quality of life in chronic hypoparathyroidism on conventional treatment

Gins Nikolay , Elfimova Alina , Kovaleva Elena , Eremkina Anna , Mokrysheva Natalia

Introduction: Reduced health-related quality of life (HRQoL) is common in patients with hypoparathyroidism (HypoPT) treated conventionally with calcium and active vitamin D supplements.Aim: we studied the HRQoL in patients with chronic HypoPT estimated with the 36-Item Short-Form Health Survey (SF-36) and multidimensional fatigue inventory (MFI-20).Methods: 64 patients with chronic HypoPT (women/men – 57/7, median age 47[36;59...

ea0081ep155 | Calcium and Bone | ECE2022

Prevalence of anemia in patients with primary hyperparathyroidism: a single-center observational study

Gorbacheva Anna , Miliutina Anastasia , Elfimova Alina , Eremkina Anna , Mokrysheva Natalia

Background The combination of primary hyperparathyroidism (PHPT) with anemia was first described in 1931. It remains unclear whether PHPT is the direct cause of anemia, or it develops as a PHPT’s complication. The etiology of anemia in PHPT could be multifactorial, including iron deficiency, renal failure as well as bone marrow fibrosis.Aim To assess the prevalence of anemia in patients with PHPT admitted to the Department of Parathyroid Glands Path...

ea0081ep626 | General Endocrinology | ECE2022

Clinical and demographic analysis of the structure of telemedicine "doctor-patient" consultations of the Endocrinology Research Centre

Gorbacheva Anna , Logvinova Oksana , Eremkina Anna , Mokrysheva Natalia

Rationale: The COVID-19 pandemic has accelerated the development of telemedicine technologies. Today there is evidence of the successful use of telemedicine in various areas of healthcare, particularly in endocrinology. At the same time, there is not enough information for efficient integration of telemedicine into the routine management of patients.Aim: The aim of this work was a clinical and demographic analysis of “doctor-patient” telemedici...

ea0090ep142 | Calcium and Bone | ECE2023

Chronic hypoparathyroidism: Predictors of complications according to the Russian Registry

Kovaleva Elena , Elfimova Alina , Eremkina Anna , Mokrysheva Natalia

Background: Chronic hypoparathyroidism is a relatively rare disease associated with various complications. The analysis of large databases of patients with chronic hypoparathyroidism is a necessary tool to enhance quality of medical care, as well as to determine the therapeutic approaches and prognostic markers of the disease.Aims: To describe complications associated with chronic hypoparathyroidism and determine predictors of their development according...

ea0090ep583 | Endocrine-related Cancer | ECE2023

Recurrent parathyroid cancer in a child associated with mutation in CDC73 gene

Kim Ekaterina , Krupinova Julia , Eremkina Anna , Kalinchenko Natalya , Mokrysheva Natalia

Background: Parathyroid cancer (P?) in children is extremely rare, more often sporadic, but may be associated with a germline mutation. The only effective treatment is surgical approach due to the chemo-radio-resistance of PC.Clinical case: A 6-years-old girl presented with weakness, gait disturbance, pain in the limbs, an X-shaped curvature of the legs. At the age of 12, the patient’s well-being worsened sharply. The laboratory examination revealed...