Searchable abstracts of presentations at key conferences in endocrinology

ea0063p59 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Adrenal pheocromocytoma during childhood – a case report

Silva Eugenia , Cunha Clara , Ferrinho Catia , Ferreira Rute , Oliveira Manuela

Pheochromocytoma is a rare tumor made up of chromaffin cells from the adrenal medulla that secrete catecholamines. It can occur at any age, with a peak incidence between the fourth and fifth decade of life, and only 10% of cases occur in children. The majority of cases are sporadic and approximately 10% are malignant. The existence of familial syndrome, multiple or extra adrenal tumors is more common at younger ages. The clinic is very variable, and hypertension (HTA) is the m...

ea0063p888 | Diabetes, Obesity and Metabolism 3 | ECE2019

Maturity onset diabetes of the young type 5 – report of one phenotype

Roque Catarina , Ferrinho Catia , Cunha Clara , Oliveira Manuela

Introduction: MODYs are being identified more frequently but the rarity of some types still precludes in-dept knowledge of their natural course of disease. One of this rare forms is MODY 5, the result of a mutation on the hepatocyte nuclear factor 1 beta (HNF-1B) gene that associates with genitourinary and pancreatic malformations/dysfunction.Case report: A 24-year-old female was referred to the Endocrinology clinic due to hyperglycaemia identified on pr...

ea0056p967 | Male Reproduction | ECE2018

Erectile Dysfunction – The hidden sickness we don’t seek

Roque Catarina , Capitao Ricardo , Ferrinho Catia , Duarte Sequeira , Vasconcelos Carlos

Introduction: Erectile dysfunction (ED) is highly prevalent and negatively impacts the patient’s and the partner’s quality of life. It is a well-established red flag for ongoing neuro-vascular disease and a predictor of coronary, cerebral and peripheral arterial disease (PAD). Our aim was to document how often do clinicians investigate ED and use it as a predictor of neuro-vascular pathology to trigger a thorough revision of cardiovascular risk factors (CVRF). This a...

ea0049ep1088 | Clinical case reports - Pituitary/Adrenal | ECE2017

Hypogonadotropic hypogonadism, functional and transitory

Roque Catarina , Serra Filipa , Santos Francisco Sousa , Ferrinho Catia , Capitao Ricardo , Bello Carlos , Vasconcelos Carlos

Functional hypogonadism has been described in association with acute severe medical or surgical illness, subacute recovery and chronic disease. We present a case of transitory hypogonadism manifested during a peri-surgical period. A 42-year-old patient was sent to the endocrinology clinic due to hypertension and a solitary adrenal mass. He was treated with bisoprolol and telmisartan, that he maintains until today. The evaluation favoured non-functional adenoma but during the f...

ea0049ep1207 | Clinical case reports - Thyroid/Others | ECE2017

Two case reports of amiodarone induced thyroid dysfunction: thyrotoxic and myxedematous crisis

Santos Francisco Sousa , Ferrinho Catia , Capitao Ricardo , Roque Catarina , Bello Carlos , Limbert Clotilde , Vasconcelos Carlos

Introduction: Amiodarone is a well-established antiarrhythmic drug frequently used in tachyarrhythmias. Side effects include hypothyroidism and hyperthyroidism. Extreme cases such as myxedematous and thyrotoxic crisis are very uncommon. Here we report one case of each of these presentations.Case Report no.1: A 73-year-old woman with history of atrial fibrillation under treatment with amiodarone presented to the emergency department with headache, nausea ...

ea0049ep1311 | Thyroid (non-cancer) | ECE2017

TSH normalization and negative anti-TSH receptor antibodies – Predictive value for remission in Graves’ disease

Roque Catarina , Santos Francisco Sousa , Capitao Ricardo , Bello Carlos , Ferrinho Catia , Vasconcelos Carlos

Graves’ disease is the most common cause of hyperthyroidism in non-endemic areas and antithyroid drugs are the preferred first-line therapy in many centers. The aim of this retrospective investigation was to verify the association of remission with the achievement of normal TSH and free-T4 during the first 18 months of treatment and to compare it with negative anti-TSH-receptor antibodies at 18 months, a marker with known prognostic value. All patients diagnosed with Grav...

ea0049ep1452 | Thyroid (non-cancer) | ECE2017

Malignant struma ovarii and synchronous tumour of thyroid gland in the same patient: a single pathway for two different tumours?

Capitao Ricardo , Saraiva Catarina , Santos Francisco , Ferrinho Catia , Roque Catarina , Bello Carlos , Vasconcelos Carlos

Background: Struma ovarii (SO) is the presence of thyroid tissue as a major cellular component in an ovarian tumour.Case report: A 35-year-old, Caucasian female, asymptomatic and with normal physical examination was submitted to left oophorectomy due to an ovarian mass (8.2×7.0×6.0 cm) detected in routine pelvic examination. Her mother also had history of oophorectomy for an ovarian tumour and partial thyroidectomy for benign thyroid nodule. Th...

ea0049ep1486 | Thyroid (non-cancer) | ECE2017

Timing to repeat thyroid fine-needle aspiration after a follicular lesion of undetermined significance result - does it matter?

Santos Francisco Sousa , Ferrinho Catia , Capitao Ricardo , Duarte Joao Sequeira , Chorao Martinha , Limbert Clotilde , Vasconcelos Carlos

Introduction: Regarding thyroid nodules, in case of follicular lesion of undetermined significance (FLUS), performing repeat fine-needle aspiration (FNA) is a common follow-up strategy. It has been suggested that a waiting period of at least 3 months between FNAs would increase the diagnostic yield. Our study aims to clarify the optimal time for repeat FNA in case of an initial FLUS result.Methods: We identified retrospectively all thyroid FNA FLUS resul...

ea0056p895 | Clinical case reports - Thyroid/Others | ECE2018

Hypergonadotropic hypogonadism secondary to vanishing testes syndrome newly diagnosed in a 42-year-old male patient

Sousa Santos Francisco , Capitao Ricardo , Ferrinho Catia , Cunha Clara , Limbert Clotilde , Vasconcelos Carlos

Introduction: Cryptorchidism is the most common abnormality of male sexual development. Approximately 5% of cases of cryptorchidism are associated with vanishing testes syndrome. This rare condition occurs when an initially normal testicle that existed in fetal life subsequently atrophies. Affected patients usually have normal male external genitalia and hypergonadotropic hypogonadism. This disease is usually diagnosed in early childhood allowing for normal sexual development ...

ea0075t12 | Thyroid | EYES2021

Febrile Neutropenia due to methimazole: a case report

Silva Eugenia , Costa Ferreira Rute , Ferrinho Catia , Sousa Santos Francisco , Gouveia Clotilde , Oliveira Manuela , Duarte Sequeira

Background: Agranulocytosis is rare and may develop in 0.2–0.5% patients using antithyroid drug therapy (ATD). We report on a patient who developed febrile neutropenia two weeks after starting treatment with methimazole.Case Report: A 74-year-old female, with no relevant medical history, was diagnosed with Graves disease and treated with methimazole (30 mg/day). Three weeks after starting therapy she presented to the emergency department with compla...