Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep685 | Thyroid | ECE2024

Early approach in a patient with an incipient thyrotoxic crisis

Jimenez Hernando Ignacio , Gomez-Gordo Hernanz Monica , Gonzalez Fernandez Laura

Introduction: Thyroid storm or thyrotoxic crisis is a severe manifestation of thyrotoxicosis. Mortality rate is 20-30%. The most common trigger is hyperthyroidism due to Graves-Basedow Disease. There are two validated scales for diagnosis: the Burch Wartofsky scale (BWPS) and the Japanese Thyroid Association scale (JTA). These scales are based on cardiovascular, neurological, digestive, and thermoregulatory clinical manifestations. If clinical suspicion is high, treatment shou...

ea0070ep4 | Adrenal and Cardiovascular Endocrinology | ECE2020

Ectopic cushing syndrome: A cases-series in a tertiary centre in Spain

Gonzalez Fernandez Laura , Brox Torrecilla Noemi , Miguelez Gonzalez Maria , Atencia Goñi Jose , Weber Bettina , Munoz Diego , Carlos Percovich Juan , Monereo Megias Susana , García Centeno Rogelio

Introduction: Ectopic Cushing Syndrome (ECS) is a rare disease associated with significant comorbidity. Among the causes of Cushing’s syndrome (CS), ACTH-producing extrahypophyseal tumours are rarely reported. The aim of our study is to describe the clinical, diagnostic and therapeutic characteristics of patients with ECS treated in our Endocrinology department over a 15-year period.Methods: A cross-sectional unicentric retrospective study was desi...

ea0099p119 | Pituitary and Neuroendocrinology | ECE2024

Management of carcinoid heart disease in neuroendocrine tumor patients: a retrospective study

Jimenez Hernando Ignacio , Gonzalez Fernandez Laura , Garcia Centeno Rogelio , Perez Noguero Marta , Gomez-Gordo Hernanz Monica , Collado Gonzalez Gloria , Losada Gata Isabel , Garcia Piorno Alberto , Gonzalez Albarran Olga

Introduction: Approximately 20% of neuroendocrine tumor (NET) patients experience carcinoid syndrome (CS), primarily associated with metastatic ileal NETs. CS manifests with symptoms such as diarrhea, flushes, and cardiac complications. Carcinoid heart disease (CHD) is a negative prognostic factor in NETs. However, the considerable variability in reported diagnoses and treatment approaches in the literature creates uncertainty about optimal management in this specific populati...

ea0099ep1014 | Adrenal and Cardiovascular Endocrinology | ECE2024

Adrenal cavernous hemangioma: a diagnostic challenge

Garcia Piorno Alberto , Losada Gata Isabel , Gomez-Gordo Hernanz Monica , Collado Gonzalez Gloria , Perez Noguero Marta , Jimenez Hernando Ignacio , Rivas Alejandra , Perez Lopez Gilberto , Gonzalez Fernandez Laura

Introduction: Cavernous hemangiomas (CH) are benign vascular tumors that frequently involve the skin, central nervous system or liver. Rarely, they can also affect adrenal glands. Adrenal cavernous hemangiomas are mostly unilateral lesions, typically discovered incidentally on radiological imaging. They generally present in the sixth to seventh decade of life and tend to be asymptomatic and non-functioning tumors. Preoperative differential diagnosis from malignant neoplasms ow...

ea0081ep695 | Pituitary and Neuroendocrinology | ECE2022

Epidemiological description of 20 years of experience in the management of insulinomas in a third level hospital

Maricel Rivas Montenegro Alejandra , Ramos Roberto Jose An ez , Belinchon Sergio Santos , Gonzalez Fernandez Laura , Moreno Diego Mun oz , Fernandez Fernandez Elisa , Salas Marcel Sambo , Hualpa Juan Carlos Percovich , Gonzalez Albarran Olga , Garcia Centeno Rogelio

Introduction: Insulinoma, despite its low incidence of 0.4%, it is the most common functioning pancreatic neuroendocrine tumor. Most are benign, solitary and sporadic. Around 10% can be malignant and 5-10% are part of MEN-1. On certain occasions, the differential diagnosis is difficult when there is a history of Diabetes Mellitus (DM). Our objective was to describe clinical-epidemiological data and its diagnostic-therapeutic management.Materials and Meth...

ea0090ep686 | Pituitary and Neuroendocrinology | ECE2023

Inferior petrosal sinus sampling and stimulation with CRH: 18 years of experience in a tertiary hospital

Montenegro Alejandra Maricel Rivas , Anez Roberto , Gonzalez Fernandez Laura , Munoz Diego , Garcia Piorno Alberto , Losada Gata Isabel , Gomez-Gordo Hernanz Monica , Collado Gonzalez Gloria , Carlos Percovich Juan , Gonzalez Albarran Olga , Garcia Centeno Rogelio

Background: Inferior petrosal sinus sampling (IPSS) is indicated in the diagnosis of adrenocor-ticotropic hormone (ACTH)-dependent Cushing’s syndrome (CS), especially when the results of the initial diagnostic tests are discordant.Objective: To describe the patients who underwent this invasive functional test in a tertiary hospital.Methods: This was an observational study of a retrospective cohort of patients with ACTH- depend...

ea0099p580 | Thyroid | ECE2024

Correlation between the expected risk of malignancy according to FNA and the actual percentage of malignancy found on pathological anatomy in thyroidectomies and hemithyroidectomies

Lopez Guerra Aurelio , Losada Gata Isabel , Gomez-Gordo Hernanz Monica , Collado Gonzalez Gloria , Perez Noguero Marta , Jimenez Hernando Ignacio , Farache Suberviola Blanca , Morales Jaurrieta Amaya , Gonzalez Fernandez Laura , Garcia Piorno Alberto

Introduction: The Bethesda system gives each Fine Needle Aspiration (FNA) category a risk of malignancy (B1: 5-10%, B2: 0-3%, B3: 10-30%, B4: 25-40%, B5: 50-75%, B6: 97-99%). Based on this risk, therapeutic decisions are made that influence the patient’s life. It is important to check whether the percentage of malignancy obtained in our daily clinical practice is similar to that expected according to this system.Aim: To check whether the percentage ...

ea0099ep392 | Adrenal and Cardiovascular Endocrinology | ECE2024

Stress cardiomyopathy secondary to pheochromocytoma

Losada Gata Isabel , Garcia Piorno Alberto , Gomez-Gordo Hernanz Monica , Collado Gonzalez Gloria , Jimenez Hernando Ignacio , Perez Noguero Marta , Morales Jaurrieta Amaya , Farache Suberviola Blanca , Gonzalez Fernandez Laura , Gonzalez Albarran Olga

Introduction: Pheochromocytoma, a rare catecholamine-secreting tumor, typically presents with paroxystic hypertension, tachycardia, headache, and diaphoresis. Less frequently, symptoms imply substantial hemodynamic compromise and cardiogenic shock may occur. The delay time in diagnosis is approximately 3 years.Case Presentation: This is a 41-year-old woman with no relevant history or cardiovascular risk factors, who presented with stress-induced cardiomy...

ea0099rc5.8 | Rapid Communications 5: Pituitary and Neuroendocrinology | Part I | ECE2024

Outcomes of transsphenoidal surgery for producing pituitary adenomas in spain

Paja Fano Miguel , Hanzu Felicia , Angeles Galvez Mª , Villar Rocio , Moure Dolores , Menendez Edelmiro , Gonzalez-Fernandez Laura , Egana Nerea , Camara Rosa , Penalver David , Simo Andreu , Asensio-Wandosell Diego , Tenorio Carmen , Novo Cristina , Calatayud Maria , Pico Antonio , Sottile Johana , Diaz-Soto Gonzalo , Penalver David , Araujo-Castro Marta , Soto Alfonso , De Pablos Pedro , Aulinas Anna , Munoz Fernando , Biagetti Betina

In our country, as in others, there is a lack of data on the success rate of transsphenoidal surgery for producing pituitary adenomas. We evaluated the results reported in TESSPAIN, a retrospective multicenter nationwide project that includes all the TSS performed in the participating centers in the period between 2018 and 2022, both included. Surgical treatment success is defined according to the published criteria for each disease: normal IGF-1 and GH after 75 g of oral gluc...

ea0099p528 | Pituitary and Neuroendocrinology | ECE2024

Predictors of diabetes remission after surgery in patients with acromegaly. a series of 604 cases

Pascual-Corrales Eider , Biaggeti Betina , Marazuela Monica , Puig-Domingo Manel , Rodriguez Berrocal Victor , Irigaray Ana , Novo Cristina , Calatayud Maria , Bernabeu Ignacio , Alvarez Escola Cristina , Tenorio Jimenez Carmen , Gonzalez-Molero Inmaculada , Iglesias Pedro , Blanco Concepcion , Paz de Miguel Novoa Maria , Lopez-Mezquita Torres Elena , Lamas Cristina , Aulinas Maso Ana , Gracia Gimeno Paola , Maria Recio Jose , Antonio Sampedro Nunez Miguel , Paja Fano Miguel , Dolores Moure Rodriguez Maria , Fajardo-Montanana Carmen , Cordido Fernando , Luis Menendez Torre Edelmiro , Carlos Percovich Juan , Garcia Centeno Rogelio , Camara Rosa , A Hanzu Felicia , Vicente Almudena , Gonzalez Fernandez Laura , Guerrero Fernando , Dolores Ollero M , Araujo Castro Marta

Aim: To investigate the impact of pituitary surgery on glucose metabolism and to identify predictors of diabetes remission after surgery in patients with acromegaly.Methods: A national multicenter retrospective study of acromegaly patients undergoing transsphenoidal surgery for the first time at 33 tertiary Spanish hospitals (ACRO-SPAIN study, n=604) was performed. Surgical remission was evaluated according to the 2000 and 2010 criteria. Glucose...