Searchable abstracts of presentations at key conferences in endocrinology

ea0035p331 | Clinical case reports Thyroid/Others | ECE2014

Thyroid papillary microcarcinoma presenting as parotid metastasis: a case report

Garcia-Arnes Juan Antonio , Maldonado Cristina , Fernandez Rosario , Gonzalo Montserrat

Differentiated thyroid carcinoma is the most common endocrine malignant tumor. Papillary carcinoma frequency in our country is 80% of thyroid neoplasia. Papillary thyroid carcinoma usually metastasizes to cervical lymph. Metastases to distant organs are rare and most often affect the lungs, liver and bones. Despite of its anatomical proximity, metastasis parotid have not been described in the existing papillary carcinomas literature. We report a case of parotid gland metastasi...

ea0032p343 | Developmental Endocrinology | ECE2013

Evaluation of adults with phenyketonuria from pediatric to adult care

Gonzalo Montserrat , Omiste Antonio , Gonzalez Inmaculada , Dominguez Marta

Objective: Transition from pediatric to adult health care is a particularly vulnerable period for patients with inborn metabolic diseases.Our objective in this study was to evaluate the current transition of patients with phenylketonuria (PKU) in Malaga, Spain, by analysis of the metabolic control, medical care, patients satisfaction and phychosocial status.Material and methods: We evaluate all the patients transferred to our adult...

ea0063p184 | Diabetes, Obesity and Metabolism 1 | ECE2019

Diagnosis of type 1 DM in a patient with Hydroxymethylglutaric aciduria: Case report

Doulatram Gamgaram Viyey Kishore , Marin Montserrat Gonzalo , Molero Inmaculada Gonzalez , Fernandez Jose Abuin , Torralvo Francisco Jose Sanchez , Adana Marisol Ruiz de , Fuster Gabriel Olveira

Introduction: Hydroxymethylglutaric aciduria is a rare metabolic disease that is caused by the deficiency of the enzyme 3-hydroxy-3-methylglutaryl-CoA lyase, which participates in the metabolism of leucine and in the formation of ketone bodies. The symptomatology usually occurs in the first two years of life and consists of nausea, vomiting, diarrhea, hypotoniaanddepressed level of consciousness. Metabolic acidosis occurs during crises as a result of the accumulation of metabo...

ea0063p200 | Diabetes, Obesity and Metabolism 1 | ECE2019

PCSK9 inhibitors effects after 2 years in real life

Gonzalez Molero Inmaculada , Marin Montserrat Gonzalo , Gamgaram Viyey Kishore Doulatram , Fernandez Jose Abuin , Garcia Ignacio Ruiz , Herrera Maria Jose Vallejo , Fuster Gabriel Olveira

Introduction: Recently, PCSK9 inhibitors have been approved in our country for familial hypercholesterolemia and for patients with cardiovascular diseases. They are still scarce data in real life patients effects.Objective: Analyse the features of first patients treated with PCSK9 inhibitors in a specific unit of familial dyslipidemia and the effect on lipid profile and other clinical variables.Material and methods: Data from patie...

ea0073aep250 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Evaluation of the results of weight loss at 1 year after bariatric surgery at the regional university hospital of malaga

Silvia Patricia Alonso Gallardo , Viyey Kishore Doulatram Gamgaram , José Abuín Fernández , Marin Montserrat Gonzalo , Sergio Valdés Hernández

IntroductionMorbid obesity is a very prevalent disease, bariatric surgery being a fundamental pillar in its treatment.ObjectiveTo analyze the results of weight loss at 1 year in patients operated on gastric bypass and sleeve at the Regional University Hospital (HRU) of Malaga.MethodsRetrospective observational study, with a follow-up period of 1 year, of 215 patie...

ea0041ep398 | Developmental endocrinology | ECE2016

Evaluation of the series of adults with inborn metabolic diseases followed in endocrinology in Andalusia (Spain)

Marin Montserrat Gonzalo , Molero Inmaculada Gonzalez , Moreno Eva Venegas , Fuentes Elena Dios , Alonso Javier Blasco , Delgado Maria Bueno , Nieto Juliana Serrano , Salinas Carlos Sierra , Fuster Gabriel Olveira , Madueno Francisco Tinahones , Moreno Alfonso Soto

Objectives: The transition from the paediatric age to the adult is a particularly vulnerable period in patients with metabolic congenital diseases (mcd). In andalusia two adultsÂ’ units exist (seville and malaga) for the follow-up of these patients. Our aim in this study was to evaluate the current series of attended patients.Material and methods: We evaluated all patients transferred to the adult units since 2008. The clinical records were analyzed ...

ea0041ep811 | Obesity | ECE2016

Positive association between blood natural killer T cells and liver enzymes ALT, AST and GGT levels

Lopez Soledad , Pozo David , Garcia-Serrano Sara , Gutierrez-Repiso Carolina , Rodriguez-Pacheco Francisca , Ho-Plagaro Ailec , Alaminos-Castillo Miguel A , Valdes Sergio , Gonzalo Montserrat , Andrade Raul J. , Garcia-Fuentes Eduardo

Introduction: Obesity is associated to a pro-inflammatory state with a different pattern of response from the classical response. Also, obesity is associated to non-alcoholic fatty liver disease (NAFLD). In this sense, natural killer T (NKT) cells are a subset of innate immune cells that abundantly reside within the liver and are readily activated by lipid antigens. However, the phenotype and functional characteristics of these cells are no clear in the immune homeostasis in o...

ea0041ep834 | Obesity | ECE2016

The level of SCD1 in subcutaneous adipose tissue is associated with the presence of metabolic syndrome in morbidly obese patients

Garcia-Serrano Sara , Gutierrez-Repiso Carolina , Rodriguez-Pacheco Francisca , Ho-Plagaro Ailec , Garcia-Escobar Eva , Alaminos-Castillo Miguel A , Garrido-Sanchez Lourdes , Valdes Sergio , Gonzalo Montserrat , Rodriguez-Canete Alberto , Montiel-Casado Custodia , Moreno-Ruiz Javier , Garcia-Fuentes Eduardo

Introduction: The stearoyl-CoA desaturase 1 (SCD1) is an enzyme involved in the metabolism of fatty acids, and seems to be involved in the regulation of atherosclerosis development. In this study we want to check the expression of SCD1 in visceral and subcutaneous adipose tissue and its relationship with the metabolic syndrome.Methods: We measured SCD1 mRNA and protein expression in visceral and subcutaneous adipose tissue from 25 morbidly obese patients...