Endocrine Abstracts

Background: Second generation antipsychotics (SGAs) are increasingly playing a bigger role in the treatment of schizophrenia and other psychiatric conditions due to their lower extra pyramidal side effect profile However, SGAs are known to cause clinically relevant metabolic derangements including hyperglycaemiaCase: A 70-year-old gentleman was admitted with generalised weakness and increased urinary frequency (polyuria) and polydipsia. His blood glucose...

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has led to unparalleled burden on national and global healthcare systems. Vaccines were viewed as way of combating Covid 19 pandemic. This led to development and implementation of vaccination programmes worldwide. Several vaccines have been approved for use in worldwide including Pfizer-BioNTech, Oxford-AstraZeneca vaccine and Moderna vaccine. Disturbingly, the speed at which these va...

Introduction: An adrenal incidentaloma is an adrenal mass lesion greater than 1 cm in diameter, which is incidentally discovered by radiological investigation. The prevalence of adrenal incidentalomas increases with age, increasing to around 3% at aged 50years and 10% in the elderly. The majority of these lesions are benign >80%. Adrenal incidentalomas fall into one of three categories: Non-functioning tumours: these lesions are benign e.g. adenomas, adrenal cysts, haemato...

Introduction: There are multiple causes of delayed puberty including constitutional delay in growth and puberty, chronic diseases, hypothyroidism, and pituitary tumours (e.g. craniopharyngioma). Delayed puberty due to macroprolactinoma is rare.Case Presentation: A 23-year-old male was reviewed in the Endocrine clinic after presenting with headaches and generally feeling unwell. Blood test showed a high prolactin level of 84637, low FT 7.7, low testostero...

Introduction: Primary hyperparathyroidism (PHPT) is the third most common endocrine disorder in the general population, with a prevalence of 0.1 to 0.4%, caused by a solitary parathyroid adenoma in 80 to 85% of cases. In pregnancy, however, it is rare and usually manifests with non-specific symptoms leading to the delay in diagnosis A 33-year-old female patient who wasreviewed in obstetrics clinic at 15/40 weeks gestation. She complained of body aches, intermitted nausea and v...

Introduction: Resolution of pituitary tumour without surgical intervention is rare. The mechanism of spontaneous resolution of pituitary adenoma is unclear but may be explained by either pituitary apoplexy or hypophysitis responding to steroids. Bray BP, et al(2021) reported the case of vanishing pituitary mass due pituitary apoplexy. Park SM, et al (2014) reported 22 cases of pituitary mass due hypophysititis which improved mostly with medical therapy.C...

Introduction: Hypothyroidism presentation can be variable. Some patients are asymptomatic whilst other present with general lethargy and cold intolerance. Depending on the degree of hormone deficiency, patient can also present with by skeletal muscle involvement characterized by muscle aches and weakness (proximal myopathy). In some cases, patients with hypothyroidism will have elevated CK but this usually less that 5000Cases: 1. 46 years old was referre...