Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep395 | Endocrine-Related Cancer | ECE2021

131I-MIBG treatment in malignant pheochromocytoma: A case report

Almeida Lucia , Alves Helena , Duarte Hugo

IntroductionA pheochromocytoma is a tumor arising from adrenomedullary chromaffin cells that commonly produces one or more catecholamines. About 80 to 85% of chromaffin-cell tumors are pheochromocytomas. It is recommended that initial biochemical testing should include measurements of plasma free metanephrines or urinary fractionated metanephrines. 123I-metaiodobenzylguanidine (MIBG) scintigraphy is a functional imaging modality, in patients w...

ea0032p568 | Endocrine tumours and neoplasia | ECE2013

Therapy with 177Lu marked somatostatin analogues in a case of pancreatic metastatic neuroendocrine tumor

Belo Sandra , Lucena Ines , Santos Ana Paula , Afonso Luis Pedro , Sanches Cristina , Duarte Hugo

Introduction: Conventional systemic therapies have limited role in metastasized neuroendocrine tumors (NET). Therefore an increasing role is attributed to 177Lu labeled somatostatin analogues (SA).Case: Man, 52 years, referred because of NET, diagnosed following liver biopsy for hepatic nodules (liver tissue infiltrated by NET, compatible with metastases). Endoscopic ultrasound revealed pancreatic nodular formation, 40×24 mm; 99</sup...

ea0032p1089 | Thyroid cancer | ECE2013

68Ga-DOTA-NOC PET/CT role in the follow-up of patients with medullary thyroid carcinoma

Couto Joana , Martins Raquel , Lucena Ines , Menezes Joana , Santos Ana Paula , Rodrigues Elisabete , Duarte Hugo , Torres Isabel

Introduction: About 50% of patients with medullary thyroid carcinoma (MTC) have persistent or recurrent disease after surgery.For a calcitonin (ct) value greater than 150 pg/ml, it is suggested by international guidelines performing additional imaging exams (AIE) for evaluating the presence of distant metastasis. It is often difficult to assess the presence of nodal disease and secondary liver lesions (often miliary) by ‘morphological’ imaging ...

ea0090p388 | Endocrine-related Cancer | ECE2023

PRRT 177Lu-DOTA-TATE in pancreatic neuroendocrine tumors – When to initiate?

Franco Sara , Lucena Sampaio Ines , Ferreira Goncalo , Barbosa Daniel , Gil-Santos Sara , Vara Luiz Henrique , Paula Santos Ana , Torres Isabel , Duarte Hugo

Introduction: The best timing for PRRT (peptide receptor radionuclide therapy) in the case of pancreatic neuroendocrine tumors (panNETs) is still to define, as randomized prospective trials are lacking. Recent studies suggest that some systemic therapies can affect response to PRRT, favoring an earlier use of the latter.Objective: To determine the efficacy and toxicity of PRRT, comparing its results when used as a second line systemic therapy (a...

ea0090ep596 | Endocrine-related Cancer | ECE2023

Case Report: Successful treatment of an atypical lung neuroendocrine neoplasm with PRRT

Guerreiro Vanessa , Lucena Ines , Paula Santos Ana , Prospero Ines , Ferreira Goncalo , Gil Santos Sara , Oliveira Joana , Freitas Paula , Torres Isabel , Duarte Hugo

Neuroendocrine neoplasms (NENs) arise from specialized cells called neuroendocrine cells spread through the body, mainly in the gastrointestinal tract, pancreas and lung. Pathological classification of Lung NENs include well differentiated NENs, that can be classified as typical or atypical carcinoids, and poorly differentiated neuroendocrine carcinomas (NECs), classified as small-cell lung carcinoma (SC-NEC) or large-cell neuroendocrine carcinoma (LC-NEC). We present a case o...

ea0063p1208 | Thyroid 3 | ECE2019

Thyroid uptake in PET-CT: IPO-porto consecutive case series

Ferreira Paulo Carvalho , Sampaio Ines Lucena , Violante Liliana Sobral , Teixeira Joao Pedro , Neves Joao Sergio , Gomes Vania Rodrigues , Mota Filipe , Duarte Hugo

Introduction: Positive radiotracer uptake by the thyroid gland can occur in PET-CT. It’s meaning has led to conflicting results mainly resulting from small studies.Objective: We aim to present a large single institution consecutive case series.Material and methods: Observational, descriptive and retrospective study of the PET-CT scans performed between the years 2000–2017. We searched the word thyroid in the computer imag...

ea0049ep1422 | Thyroid (non-cancer) | ECE2017

Incidental thyroid uptake detected by 68Ga-DOTANOC positron Emission Tomography: is it clinical significant?

Silva Tiago Nunes da , Santos Joaquim Gomes , Matos Ana Catarina , Teixeira Joao Pedro , Oliveira Carla , Castanheira Joana , Carmona Susana , Duarte Hugo , Costa Durval , Oliveira Luis , Santos Ana Isabel , Portugal Jorge

Background: The detection of thyroid incidental uptake of radiopharmaceuticals has been increasing. Those detected by 18F-fluorodeoxyglucose positron emission tomography (PET) have been associated with a significant risk of malignancy (8–64%). Gallium-68 (Ga-68) labelled peptides are now the standard imaging modality for staging neuroendocrine tumours (NET). Its high sensitivity has increased the discovery of incidental findings. The aim of this study was to ev...