Searchable abstracts of presentations at key conferences in endocrinology

ea0081p454 | Reproductive and Developmental Endocrinology | ECE2022

Different grade of obesity influences the association between 25-hydroxyvitamin and Testosterone levels: A cross-sectional study in young Spanish men with Obesity

Boughanem Hatim , Damas-Fuentes Miguel , Vega Maria Molina , Jose Tinahones Madueno Francisco , Carlos Fernandez Garcia Jose , Macias Manuel

Backgrounds: One of the most observations in subjects with obesity, is a high prevalence of vitamin D deficiency, which, in turn, it has been implicated with decreased testosterone levels and an increased hypogonadism risk. Testosterone deficiency is a very common feature in males with obesity. However, only few studies have investigated the effect of vitamin D on testosterone in the context of obesity, and controversial results has been found.Hypothesis...

ea0063p622 | Diabetes, Obesity and Metabolism 2 | ECE2019

Assessment of materno-fetal complications in pregnant women with type 1 diabetes exposed to insulin degludec

Martinez Montoro Jose Ignacio , Hernandez Garcia Carmen , Jose Picon Cesar Maria , Molina Vega Maria , Maria Diaz Perdigones Cristina , Damas Fuentes Miguel , Jose Tinahones Madueno Francisco

Introduction: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of adverse outcomes, so pregnancy planning in order to achieve an optimal glycemic control is essential. This control has been made possible, in part, by the widespread use of insulin analogues, especially the long-acting ones, glargine and detemir. Insulin degludec, an ultra-long-acting insulin is not currently approved for pregnant women due to the lack of randomized co...

ea0056p16 | Adrenal cortex (to include Cushing's) | ECE2018

Rare incidence of primary adrenocortical carcinosarcoma: a case report

Maria Diaz Perdigones Cristina , Maria Cornejo Pareja Isabel , Damas Fuentes Miguel , Molina Vega Maria , Hernandez Garcia Carmen , Munoz Garach Araceli , Jose Tinahones Madueno Francisco

Introduction: Adrenal tumors are common tumors with a prevalence of around 3% in a population over the age of 50 years. In contrast, adrenocortical carcinoma (ACC) is a rare malignancy (incidence 1–2 per 1 million population) with a heterogeneous presentation and a variable but generally bad prognosis. Patients present with evidence of adrenal steroid hormone excess in approximately 60% of cases.Case report: A 49-year-old woman with symptoms of faci...

ea0081ep1021 | Thyroid | ECE2022

Clinical experience with tyrosine kinase inhibitors in radioiodine-refractory differentiated thyroid cancer

Fernandez Valero Andrea , Damas-Fuentes Miguel , Montoro Jose Ignacio Marti nez , Vega Maria Molina , Doblas Isabel Mancha , Garcia Aleman Jorge , Ochoa Arantzazu Sebastian , Manuel Trigo Perez Jose , Jose Tinahones Madueno Francisco

Introduction: Differentiated thyroid cancer (DTC) represent 85- 90 % of all thyroid cancer cases. Most of these have an excellent prognosis with standard treatment. However, between 7 and 23% will develop distant metastases and, of these, more than 65% will become radioactive iodine-refractory. In some of these patients who are considered to be radioiodine-refractory with rapidly progressive or symptomatic disease, or in patients who are not candidates for other therapies, the...