Searchable abstracts of presentations at key conferences in endocrinology

ea0078dmd1.3 | Symposium 1 | BSPED2021

Personalising insulin therapy using smart pumps, pens and automated insulin delivery systems

Mader Julia K.

People living with diabetes face the daily burden of managing their disease. The ongoing challenge of administering insulin, testing heir glucose and adhering to recommended lifestyle can be overwhelming. Diabetes technology can alleviate some of this burden. However, the technology should be chosen wisely upon preferences and competences of affected people. Insulin pump use has been increasing over the last decades. Insulin pumps re considered a comfortable way to deliver ins...

ea0041ep569 | Diabetes therapy | ECE2016

Combined metformin-associated lactic acidosis and euglycaemic ketoacidosis

Schwetz Verena , Eisner Florian , Schilcher Gernot , Eller Kathrin , Plank Johannes , Lind Alice , Pieber Thomas R , Mader Julia K , Eller Philipp

Introduction: In metformin-associated lactic acidosis with renal dysfunction inhibition of hepatic gluconeogenesis by drug accumulation may aggravate fasting induced-ketoacidosis. We report the occurrence of metformin-associated lactic acidosis with concurrent euglycemic ketoacidosis in three patients with renal failure.Cases: The first patient was a 79-year-old woman who suffered from chronic kidney disease stage IIIa after traumatic uninephrectomy, and...

ea0022p344 | Diabetes | ECE2010

Systemic effect of insulin on local cytokine concentrations in adipose tissue and muscle in healthy humans

Mader Julia K , Ikeoka Dimas , Weinhandl Heinz , Pachler Christoph , Bock Gerlies , Plank Johannes , Ellmerer Martin , Pieber Thomas R

Introduction: Cytokines are produced in different tissues under physiological and pathophysiological conditions. The present study was performed to compare local concentrations of cytokines in subcutaneous adipose tissue and muscle using the open flow microperfusion (OFM) technique, as well as to investigate systemic effects of insulin on interstitial concentrations of these mediators.Methods: Ten healthy volunteers (age: 27±4 years, BMI: 22.6±...

ea0049ep609 | Diabetes therapy | ECE2017

Increase in time in target when using a basal-bolus algorithm for insulin dosing with insulin glargine U300 during hospital stay

Mader Julia K , Donsa Klaus , Aberer Felix , Lichtenegger Katharina , Lanz Christian , Smajic Edin , Holl Bernhard , Beck Peter , Pieber Thomas R , Plank Johannes

Background and aims: Insulin therapy and the use of clinical decision support systems to achieve glycaemic control in hospitalized patients with hyperglycaemia are recommended by clinical guidelines. The aim of this evaluation was to assess time in target by continuous glucose monitoring (CGM) achieved by a basal-bolus insulin algorithm using insulin glargine U300 during hospital stay in patients with type 2 diabetes (T2D).Material and methods: 30 patien...

ea0041ep546 | Diabetes therapy | ECE2016

Evaluation of three continuous glucose monitoring systems during exercise and meal challenges

Mader Julia K , Hajnsek Martin , Aberer Felix , Rumpler Markus , Zenz Sabine , Puffing Adelheid , El-Sayed Hesham , Baumann Petra , Sinner Frank , Pieber Thomas R

Introduction: Continuous glucose monitoring (CGM) has become an essential tool in diabetes management. In order to use CGM for treatment decisions, CGM systems have to be reliable over a wide range of glycemia as well as in situations with rapidly changing glucose levels such as exercise or in the postprandial state.Design: In this monocentric study we evaluated the performance of three commercially available CGM systems (Abbott Libre, Dexcom G4 Platinum...

ea0104p70 | Diabetes & Metabolism | SFEIES24

Association between impaired awareness of hypoglycaemia and psychological outcomes in people living with insulin-treated type 2 diabetes

McCarthy Aisling , Divilly Patrick , Zaremba Natalie , Martine-Edith Gilberte , Soholm Uffe , de Galan Bastiaan , Pedersen-Bjergaard Ulrik , McCrimmon Rory J. , Renard Eric , Heller Simon , Evans Mark , Mader Julia K. , Amiel Stephanie A. , Pouwer Frans , Choudhary Pratik

Background: Impaired awareness of hypoglycaemia (IAH) is associated with impaired psychological health in people living with type 1 diabetes (T1D). We explored the differences in anxiety, depression and diabetes distress according to hypoglycaemia awareness in people living with insulin-treated type 2 diabetes (T2D).Methods: This analysis included 321 T2D participants from the Hypo-METRICS study. Participants completed the General Anxiety Disorder-7 (GAD...