Endocrine Abstracts

In 162 patients with end-stage renal disease (ESRD), 112 on maintenance haemodialysis (HD) and 50 on continuous ambulatory peritoneal dialysis (CAPD), thyroid status was evaluated: thyrotropin (TSH, IRMA, normal range 0.15–5 mU/l), total thyroxine (TT4, RIA, 70–140 nmol/l), free thyroxine (FT4, RIA, 11–25 pmol/l), total triiodothyronine (TT3, RIA, 1–3 nmol/l), free thyroxine (FT3, RIA, 2.5–5.8 pmol/l); in 113 patients (63+50) also reverse T3 (RT3, RIA,...

Screening of thyroid disorders in pregnancy has been a matter of controversy. Recent recommendations favour targeted high-risk case finding though this approach may miss a significant number of those affected (Vaidya et al. JCEM 2007).Among 398 non-selected women in the 10th week of pregnancy, thyrotropin (IRMA) >3.5 mIU/l was found in 10.3%, free thyroxine (RIA) <10 pmol/l in 2% and thyroperoxidase antibodies (RIA) >50 IU/ml in...

Introduction: In end-stage renal disease (ESRD), thyroid function tests are often abnormal, and their interpretation is not always straightforward. While haemodialysis (HD) procedure has well-established profound effects on the serum levels of a variety of molecules no such data have been published on thyroid hormones.Methods: In 110 ESRD patients, total and free thyroxine (T4 and fT4), total and free triiodothyronine (T3...