Endocrine Abstracts

Background: The inflammation of the pituitary gland known as hypophysitis. It is a rare disease accounting for approximately 0.24–0.88% of all pituitary diseases. Main forms of hypophysitis are histologically classified as lymphocytic, granulomatous, IgG4 related and xanthomatous. We aim to present ourpatients of hypophysitis with clinical,laboratoryand radiological features.Methods: We retrospectively reviewed our database of 1293 patients diagnose...

Introduction: Ectopic parathyroid adenomas are detected 16% of patients operated for primary hyperparathyroidism and 22% of them may be located in the anterosuperior mediastinal region. Herein we present a rare case of primary hyperparathyroidism with severe long-term elevated parathormone (PTH) levels due to ectopic parathyroid adenoma in mediastinal region that was successfully treated by using video-assisted thoracic surgery (VATS).Case report: A 38-y...

Introduction: Differentiated thyroid cancers (DTC) are the most frequently occuring endocrine malignancies. The factors determine the recurrences and metastases are whole body scanning (WBS) and either suppressed or stimulated thyroglobulin (sTg) levels. The aim of this study to evaluate the preablative factors predict of radioiodine remnant ablation (RRA) therapy success.Patients and methods: One hundred consecutive patients with DTC (94 papillary and s...

ObjectiveThere is limited clinical data available on bilateral adrenal masses (BAM). Here we present a case with BAC and adrenal insufficiency. The patient’s lesions disappeared after steroids, re-grew in the follow-up, allowing a biopsy.CaseA 60-year-old male patient presented with abdominal pain, nausea, and weakness to another hospital. Hyponatremia and hyperkalemia accompanied by hypotension were det...

Introduction: Metformin is widely used as the first-line therapy for patients with type 2 diabetes, and its most common adverse effects are gastrointestinal. Metformin-associated lactic acidosis (MALA) is a rare but serious adverse effect in patients with type 2 diabetes or patients who attempt suicide with metformin overdose. Here, we report the case of a 22-year-old woman who developed severe lactic acidosis after high-dose metformin was taken for a suicide attempt.<p cl...

Aim: The aim of the present study was to evaluate the characteristic features of computerized tomography (CT) and magnetic resonance imaging (MRI) among functioning and non-functioning adrenal lesions.Materials and methods: We retrospectively reviewed the medical records of patients with adrenal mass. CT or MRI findings were available in 89 functioning and 148 non-functioning adrenal lesions (NFAL). Of the patients with functioning adrenal mass, 34 were ...

İntroduction: CNS involvement is rare in acute monocytic leukemia cases. Pituitary involvement seems much more rarely with unknown frequency. Here, we present a case of AML- M5 (FAB classification) patient with pituitary involvement.Case presentation: A 29 years old, male patient, admitted to hematology clinic with visual disturbance and poor performance status. Allogeneic hematopoietic stem cell transplantation was performed in 2010 after chemothe...

Introduction: It’s well known that any form of diabetes insipidus (DI) can be exacerbated or first become appearent during pregnancy, since increased catabolism of ADH by plasental vasopressinas enzyme. Postpartum DI cases mostly presenting as a part of Sheean syndrome and began after postpartum first days. There was no any published case of isolated DI that began in the 6th month after deliveration in current literature.Case: A 37...

Introduction: There are two clinical types of amiodarone induced thyrotoxicosis (AIT). Type I AIT appears with hyperthyroidism and type II with a destructive thyrotoxicosis. Treatment of type I AIT includes antithyroid drugs meanwhile type II needs steroids as the first line therapy. If there is no respond to medical treatment, surgical approach must be considered. Here in we present a type II AIT case who had no respond to combined therapy therefore treated with surgical appr...

BackgroundCytochrome P450 oxidoreductase (POR) deficiency is an autosomal recessive steroidogenesis disorder similar to combined deficiencies of 17a-hydroxylase, 17, 20-lyase, 21-hydroxylase. POR deficiency (PORD) is a very rare type of congenital adrenal hyperplasia(CAH) characterized by sexual development disorders and skeletal anomalies. We present a case that was evaluated with a prediagnosis of nonclassical CAH and was found to have a heterozygo...