Searchable abstracts of presentations at key conferences in endocrinology

ea0035p889 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Acromegalic arthropathy: clinical presentation, treatment and quality of life

Nunes Joana Menezes , Rodrigues Elisabete , Carvalho Davide

Introduction: Arthropathy affects the majority of acromegalic patients and is a major cause of morbidity, absenteeism and impaired quality of life. GH excess and increased levels of circulating IGFI result initially in a marked thickening of the soft tissues and cartilage. Along with disease progression, there’s subperiostal bone neoapposition, cartilage regressive phenomena and bone structural changes. We aimed to investigate prevalence, clinical presentation, treatment ...

ea0032p128 | Calcium and Vitamin D metabolism | ECE2013

Late-onset hypoparathyroidism 15 years after thyroidectomy

Nunes Joana Menezes , Rodrigues Elisabete , Carvalho Davide

Introduction: Post-surgical hypoparathyroidism is a well known complication of total thyroidectomy. It may occur as transitory hypoparathyroidism that spontaneously recover within a few weeks/months and as permanent hypoparathyroidism needing long-term treatment. Only few cases of hypoparathyroidism newly diagnosed many years after surgery have been reported. We present a patient with hypoparathyroidism that became clinically evident 15 years after the thyroid surgery.<p c...

ea0037ep545 | Obesity and cardiovascular endocrinology | ECE2015

Calculating serum LDL cholesterol (LDL-C): comparison of LDL-C measured by direct assay with various formulae by combination of ages, genders, and triglycerides

Nunes Joana Menezes , Rodrigues Elisabete , Carvalho Davide , Guimaraes Joao Tiago

Introduction: LDL cholesterol (LDL-C) is a major risk factor for atherosclerosis. The Friedewald formula (FF) is limited by hypertriglyceridaemia. We aimed to correlate serum LDL-C measured by direct assay with serum LDL-C estimated by several formulas: Friedewald (FF): LDL-C=CT-HDL−TG/5; Tsai (TsaiF): LDL-C=TC-HDL−TG/8 (TG/8 represents very-LDL-C); DeLong (DeLongF): LDL-C=TC-HDL−TG×0.16 and Chen (ChenF): LDL-C=non-HDL-cholesterol×0.9−TG×...

ea0037ep1299 | Clinical Cases–Thyroid/Other | ECE2015

Graves' orbitopathy coursing with hypothyroidism: a case-report

Saavedra Ana , Nunes Joana Menezes , Rodrigues Elisabete , Ribeiro Sara , Leal Victor , Carvalho Davide

Introduction: Graves’ orbitopathy is usually associated with Graves’ Disease, which is typically characterized by hyperthyroidism and goiter. However, in rare situations, Graves’ disease can also present with hypothyroidism and orbitopathy.Case report: Male, 38 years old, followed by his ophthalmologist for thyroid orbitopathy (exophthalmos right>left and conjunctival hyperaemia since 1 year ago) associated with asthenia, tiredness and...

ea0037gp.25.03 | Thyroid – nodule | ECE2015

Malignancy rate in thyroid nodules with AUS/FLUS cytology in a Cancer Center (Bethesda System for Reporting Thyroid Cytopathology 2009)

Nunes Joana Menezes , Martins Raquel , Santos Jacinta , Martins Teresa , Moniz Ana Paula , Ilheu Olga , Figueiredo Paulo , Rodrigues Fernando

Introduction: The Bethesda System for Reporting Thyroid Cytopathology is the standard for interpreting fine-needle aspiration (FNA) and created a new diagnostic category (III): ‘atypia of undetermined significance/follicular lesion of undetermined significance’ (AUS/FLUS). The risk of malignancy for this category has been ascribed of 5–15% but the real malignancy rate remains unclear and plays a key role to define appropriate management.Ob...

ea0032p717 | Neuroendocrinology | ECE2013

Craniopharyngioma – a diagnosis not to be missed

Nunes Joana Menezes , Rodrigues Elisabete , Salvador Sergio , Cerejo Antonio , Reis Ricardo , Silva Sergio , Augusto Luis , Guimaraes Marcos , Vaz Rui , Carvalho Davide

Introduction: Craniopharyngiomas are intracranial tumors that develop from Rathke’s pouch rests of epithelium. They have a bimodal age distribution, with peak incidence at childhood and in the adult/elderly, although in our series we have more patients in a middle peak. Usually they are benign but responsible for significant morbidity, particularly when located near critical structures such as optic chiasm, pituitary gland and hypothalamus, and thus might cause visual, ne...