Searchable abstracts of presentations at key conferences in endocrinology

ea0029pl8 | Novel molecular link between the circadian clock and hypertension | ICEECE2012

Novel molecular link between the circadian clock and hypertension

Okamura H.

Rhythmic change of the internal milieu is a fundamental principle in all living organisms. A variety of physiological events show daily rhythms, such as blood pressure, hormonal secretion, cell cycle, and migration of stem cells from the bone marrow to the systemic circulation. This timing is determined by the endogenous oscillatory system called the circadian clock. Within the last ten years, the molecular dissection of circadian clock has progressed dramatically, and it is n...

ea0029p644 | Diabetes | ICEECE2012

Association of cardio-ankle vascular index with diabetes mellitus-related peripheral arterial disease in chronic hemodialysis patients

Okamura A , Furuya F , Akiyama D , Shimura H , Motosugi A , Haraguchi K , Kobayashi T

Introduction: Peripheral arterial disease (PAD) is increased associated with an accumulation of patients with end stage kidney disease and diabetes. Recently, the cardio-ankle vascular index (CAVI) has been developed as an index reflecting the stiffness of the aorta independently of blood pressure. The aim of this study was to assess the prevalence of PAD in hemodialysis patients with diabetes.Methods: To examine the usefulness of CAVI to screen for the ...

ea0073aep200 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

IL-18 in the Glucose Continuum

Nedeva Iveta , Gateva Antoaneta , Assyov Yavor , Karamfilova Vera , Velikova Tsvetelina , Yamanishi Kyosuke , Kamenov Zdravko , Okamura Haruki

BackgroundBoth obesity and diabetes are associated with chronic low-grade inflammation. IL-18 is a cytokine that stimulates various cell types and has pleiotropic functions. The aim of the present study was to investigate the circulating levels of IL-18 in different stages of glucose dysregulation from obesity through prediabetes to newly diagnosed diabetesMethodsIL-18 levels were determined using a commercia...

ea0081ep1163 | Late Breaking | ECE2022

Sex difference in the association of cortisol excess severity with osteoporosis and osteopenia prevalence in cortisol-producing adrenal adenoma

Izawa Shoichiro , Matsumoto Kazuhisa , Matsuzawa Kazuhiko , Katabami Takuyuki , Yoshimoto Takanobu , Otsuki Michio , Sone Masakatsu , Takeda Yoshiyu , Okamura Shintaro , Ichijo Takamasa , Tsuiki Mika , Suzuki Tomoko , Naruse Mitsuhide , Tanabe Akiyo

Objective: Osteoporosis and osteopenia (OS/OP) are frequent in patients with cortisol-producing adrenal adenomas (CPA) associated with severity of cortisol excess (CE). However, the relationship between OS/OP and CE severity considering sex differences is unknown.Patients and Methods: This was a retrospective cross-sectional observational study conducted as a part of the Advancing Care and Pathogenesis of Intractable Adrenal Disease in Japan (ACPA-J) stu...

ea0092ps1-02-01 | Graves’ Disease | ETA2023

Preoperative management of graves’ disease: should all patients be euthyroid?

Tomoda Chisato , Ono Reiko , Yoshioka Kana , Saito Yoshiyuki , Masaki Chie , Akaishi Junko , Hames Yamada Kiyomi , Okamura Ritsuko , Suzuki Akifumi , Matsuzu Ken-ichi , Kitagawa Wataru , Sugino Kiminori , Ito Koichi

Context: Prior to thyroidectomy for GravesÂ’ disease, thyroid function should be adequately controlled to avoid complications such as thyroid storm. However, preoperative thyroid function control is sometimes difficult.Objective: This study assessed the postoperative risks are increased or not if biochemically hyperthyroid patients undergoing total thyroidectomy in comparison to euthyroid patients.Methods: A retrospective, coho...