Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep615 | Endocrine-Related Cancer | ECE2022

Frequency of CYP1B1 gene polymorphism in obese and non-obese women with hormone-dependent endometrial cancer

Ilic Dusan , Ognjanovic Sanja , Popovic Bojana , Elezovic Valentina , Opalic Milica , Radic Lena , P. Macut Djuro

Aim: There is a significant link between the increased activity of estrogen and its metabolites in endometrial carcinogenesis. Polymorphisms of the gene involved in metabolism of estrogen can modulate risk for the development of endometrial cancer. CYP1B1 plays an important role in estrogen metabolism. In our study, the frequency of three CYP1B1 gene polymorphisms (4326 C> G, 4390 A> G and 355 G> T) were studied in obese and non-obese women with endometrio...