Searchable abstracts of presentations at key conferences in endocrinology

ea0081rc1.3 | Rapid Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2022

Plasma amino acid profile in women with polycystic ovary syndrome and its correlation with metabolic disturbances

Paczkowska Katarzyna , Rachon Dominik , Berg Andrzej , Siomkajlo Marta , Rybka Jacek , Kapczynska Katarzyna , Bolanowski Marek , Daroszewski Jacek

Background: Polycystic ovary syndrome (PCOS) is a heterogenous endocrinopathy commonly diagnosed in reproductive age women, predisposing to the development of metabolic disturbances. However, the mechanisms underlying the connection between PCOS and metabolic disorders are still not well understood. The aim of the study was to investigate amino acid (AA) profile in women with PCOS and to assess its relation with metabolic disturbances.Methods: 326 women:...

ea0070yi7 | Young Investigators | ECE2020

Congenital isolated follicle-stimulating hormone deficiency due to the FSHB gene mutation in a female patient – a rare case report

Paczkowska Katarzyna , Kolanowska Monika , Wikiera Beata , Bolanowski Marek , Jażdżewski Krystian , Daroszewski Jacek

Introduction: Mutations in FSHβ gene leading to isolated follicle-stimulating hormone (FSH) deficiency are very rare and the disorder is inherited in an autosomal recessive manner. Up to date, only few case reports have been described in the literature.Case report: 25-years old woman was admitted to the Endocrinology Department with a suspicion of FSH deficiency. She was firstly diagnosed with primary amenorrhoea and impaired pubertal development at...

ea0090p723 | Reproductive and Developmental Endocrinology | ECE2023

Early markers of metabolic disorders, such as leucin and isoleucine level and lipid accumulation product, should be considered as the potential additional criterium in PCOS classification

Paczkowska Katarzyna , Rachoń Dominik , Berg Andrzej , Rybka Jacek , Kapczyńska Katarzyna , Bolanowski Marek , Daroszewski Jacek

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects reproductive age women and predispose to the development of metabolic disturbances. However, Rotterdam criteria, commonly used to diagnose and classify this disorder, do not include metabolic markers. Recent research has shown that several metabolic factors may play a role in PCOS pathogenesis. Branched-chain amino acids (BCAA) are the group of essential amino acids including leucine, isol...

ea0070aep978 | Thyroid | ECE2020

Large ‘forgotten goiter’ in the thoracic cavity – a case report

Paczkowska Katarzyna , Rolla Małgorzata , Elbaum Michał , Jędrzejuk Diana , Bolanowski Marek , Daroszewski Jacek

Introduction: ‘Forgotten goiter’ is defined as a mediastinal thyroid mass discovered after total thyroidectomy. It is a rare clinical finding, usually asymptomatic.Case report: 88-years old woman was admitted to the Endocrinology Department with a suspicion of the retrosternal goiter. In her medical history there was thyroidectomy performed 16 years before because of multinodular goiter and she had recurrent lower respiratory tract infections...

ea0063p841 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Malignant paraganglioma of the urinary bladder-diagnosis and management – a case report

Gilis-Januszewska Aleksandra , Rzepka Ewelina , Paczkowska Katarzyna , Bryk Agata , Walczyk Joanna , Morawiec-Sławek Karolina , Pantofliński Jacek , Sowa-Staszczak Anna , Opalińska Marta , Pach Dorota , Hubalewska-Dydejczyk Alicja

Introduction: Paragangliomas (PGL) are rare tumours of neuroendocrine origin. Those localized in urinary bladder account for 10% of all PGL. They arises from chromaffin tissue of the sympathetic nervous system that is embedded in the muscle layer of the bladder wall. Approximately 10% of urinary bladder paragangliomas are malignant.Case presentation: A 76-year-old female presented with a history of haematuria, hypertension, headaches and excessive sweati...