Searchable abstracts of presentations at key conferences in endocrinology

ea0090p18 | Adrenal and Cardiovascular Endocrinology | ECE2023


Saraiva Miguel , Palma Isabel

Introduction: Some studies have already described an association between mild autonomous cortisol secretion and poorer bone quality and increased risk of fracture. However, no consensus exists on this topic and currently there are no guidelines recommending bone status evaluation in patients suffering from this condition.Aims: To evaluate bone mineral density in patients diagnosed with autonomous cortisol secretion (ACS) and possible autonomous cortisol ...

ea0041ep12 | Adrenal cortex (to include Cushing's) | ECE2016

Nonfunctional adrenal incidentalomas and cardiometabolic risk

Ferreira Lia , Palma Isabel

Background: Incidentally discovered adrenal tumours have become a common clinical problem. The presence of an adrenal incidentalomas has been associated with an increase incidence of several cardiovascular risk factors. These abnormalities are more frequent in patients with clinical and subclinical hypercortisolism, nevertheless some studies have reported an association between nonfunctioning adrenal incidentalomas (NFAIs) with increased insulin resistance and cardiovascular r...

ea0090p194 | Reproductive and Developmental Endocrinology | ECE2023

Masculinizing Hormone Therapy: What Happens to Estradiol and To Total, Free and Biovailable Testosterone?

Saraiva Miguel , Ferreira Lia , Palma Isabel

Introduction: Masculinizing Gender-Affirming Hormone Therapy (GAHT) generally aims to induce testosterone levels equivalent to those of cisgender men and to reduce estradiol levels. There are no studies about bioavailable testosterone in this population.Aims: To determine the variation of the serum levels of sexual hormones in transmasculine people under GAHT and study the correlations between them and with BMI.Methods: Longitudina...

ea0081p187 | Reproductive and Developmental Endocrinology | ECE2022

Overall impact of gender affirming hormone therapy: the portuguese experience

Saraiva Miguel , Santos Rafael , Figueiredo Zelia , Lemos Carolina , Palma Isabel

Introduction: The prevalence of Transgender individuals seeking gender affirming hormone therapy (GAHT) has been increasing. This therapy has been known to be highly effective in the treatment of gender dysphoria and enhancing mental health in this population.Aim: To evaluate the overall impact of GAHT on self-esteem, well-being and social/familial relations in the Portuguese adult transgender populationMethods: Cross-sectional stu...

ea0090ep92 | Adrenal and Cardiovascular Endocrinology | ECE2023

A case of a black adrenal adenoma with autonomous cortisol secretion

Cidade-Rodrigues Catarina , de Brito Marques Francisca , Palma Isabel

Introduction: Adrenal incidentalomas are a frequent finding (1.4-7.3% on abdominal CT) and increasingly common with age, obesity, diabetes and hypertension. When approaching adrenal masses, clinicians should exclude malignancy and hormonal hypersecretion. Black adrenal adenomas (BAA), first reported in 1938, are rare benign adrenocortical tumours with black/brown appearance, containing lipofuscin. Most are non-functional, rarely inducing hypercortisolism. We present a case of ...

ea0056p63 | Adrenal cortex (to include Cushing's) | ECE2018

Salivary cortisol as a diagnostic tool for hypercortisolism in Cushing’s syndrome and adrenal incidentaloma

Ferreira Lia , Amaral Claudia , Palma Isabel , Cardoso Helena

Background: The lack of circadian rhythm is a marker of Cushing’s syndrome (CS). Therefore, salivary cortisol rhythm has been suggested for studies on the hypothalamic–pituitary–adrenal (HPA) axis. Late-night salivary cortisol has been used recently by many centers as a first line diagnostic test for CS, yet its accuracy is still on debate.Aim: To evaluated the performance of morning and late night salivary cortisol in patients with CS and...

ea0056p259 | Calcium & Vitamin D metabolism | ECE2018

Primary hyperparathyroidism: a rare cause of hypertension?

Lopes Ana , Palma Isabel , Teixeira Sofia , Cardoso Helena

Backgroud: Primary hyperparathyroidism is the most common cause of hypercalcemia, which is associated with an increased frequency of hypertension. However, there are no data on the prevalence of primary hyperparathyroidism in patients who present with hypertension.Clinical case: We present the case of a 40-year-old woman with a history of hypertension for ten years. In 2017 she was referred for evaluation of hypercalcemia. The patient denied any symptoms...

ea0081ep920 | Reproductive and Developmental Endocrinology | ECE2022

Safety and monitoring of gender affirming hormone therapy in portugal

Saraiva Miguel , Santos Rafael , Figueiredo Ze lia , Lemos Carolina , Palma Isabel

Introduction: The prevalence of Transgender individuals seeking gender affirming hormone therapy (GAHT) has been increasing. It is important to closely monitor this therapy in order to minimize the risk of adverse effects.Aim: To evaluate the safety and monitoring of the GAHT in the Portuguese adult transgender populationMethods: Cross-sectional study conducted in March 2021. Data collected through an online questionnaire ...

ea0063p839 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

When MAX runs in the family

Duarte Diana Borges , Pereira Catarina A , Palma Isabel , Carvalho Rui , Cardoso Helena

Introduction: Recent advance of genetic testing has contributed to the diagnosis of hereditary pheochromocytoma and paraganglioma (PPGL). Germline mutations in MYC associated factor X(MAX) are responsible for 1.1% of these PPGL; the median age at onset is 33 years and no reliable penetrance estimation is available for MAX-carriers. The authors present the case of a synchronous bilateral pheochromocytoma that prompted the discovery of a proband of MAX mutation and three other r...

ea0049ep350 | Endocrine tumours and neoplasia | ECE2017

A suspicious case of multiple endocrine neoplasia

Pereira Teresa Alves , Furtado Ines , Amado Ana , Ferreira Lia , Almeida Raquel , Palma Isabel

Introduction: Multiple endocrine neoplasia (MEN) syndromes are rare entities characterized by the occurrence of tumors involving two or more endocrine glands in a single patient. These syndromes are classified as type 1 or 2 according to specific phenotypic characteristics. MEN2 encompasses three different subtypes: MEN2A, MEN2B and familial medullary thyroid carcinoma. More recently a syndrome related to mutations in the CDKN1B gene has been described – the syndrome of m...