Endocrine Abstracts

Introduction: Calcitonin (CT) is the most specific marker for medullary thyroid carcinoma (MTC), thus, even low detectable values can conceal persistent disease. Current guidelines suggest performing an early CT evaluation three months after surgery. However, this timing may be too premature to evaluate the CT nadir, since different isoforms or aggregates from tumour deposits may persist in the bloodstream and require additional time to be cleared. The present study aimed to e...

Introduction: Indeterminate cytology still puzzles clinicians, due to its wide range of oncological risks. The new Italian cytological classification introduced in 2014 by SIAPEC-IAP split this category into TIR3A and TIR3B, according to a different cancer risk of <10% and <30%, respectively. Consequently, TIR3B nodules still have a surgical indication, even if more than half of cases will not result in thyroid cancer. The present study aims to analyse a consecutive se...

Objectives: Recommending general dynamic penile color doppler ultrasound (D-PCDU) screening in patients with erectile dysfunction (ED) has been questioned due to an inadequate cost-benefit ratio. The aim of the present study is to asses the validity of different risk scores in the identification of patients being screened for arteriogenic ED at D-PCDU.Design and methods: A consecutive series of 738 (mean age 53.6±9.2 years) patients with ED was stud...

Objectives: The aim of present study is to determine psychobiological characteristics of sexual dysfunction (SD) associated with metabolic syndrome (MS; as defined by National Cholesterol Education Program’s Adult Treatment Panel III, NCEP-ATP-III criteria) in a consecutive series of 803 male out-patients.Methods: Several hormonal, biochemical and instrumental (penile doppler ultrasound, PDU) parameters were studied, along with psycho...

Objectives: The physiological role of prolactin in male sexual function has not been completely clarified. Aim of this study is the assessment of clinical features and of conditions associated with hyperprolactinemia in male patients consulting for sexual dysfunction.Design and methods: A consecutive series of 2146 (mean age 52.2±12.8 years) male patients with sexual dysfunction was studied. Several hormonal and biochemical parameters were studied a...

Objectives: Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) are characterized by insulin resistance and often associated with male hypogonadism. To discriminate the specific contribution of T2DM and MetS to male hypogonadism.Design and methods: A consecutive series of 1134 (mean age 52.1±13 years) male patients with sexual dysfunction was studied. Several hormonal and biochemical parameters were studied along with ANDROTEST, a 12-item ...

Objectives: The aim of present study was to verify possible differences in the prevalence of vasculogenic ED and hypogonadism comparing two distinct new definitions of MetS, as National Cholesterol Education Program-Third Adult Treatment Panel (NCEP-ATPIII) and International diabetes Federation (IDF) in patients with sexual dysfunction.Methods: Several hormonal, biochemical and instrumental (penile doppler ultrasound) parameters were studied. ANDROTEST S...

Objectives: Detecting hypogonadism is crucial in patients with sexual dysfunctions because hypogonadism can have a causal role for them and testosterone (T) substitution represents a milestone for the therapy. At present, three different inventories have been developed for screening of hypogonadism in aging male. All these instruments demonstrated a good sensitivity but low specificity. No inventories are available for the screening of hypogonadism in patients with sexual dysf...

Objectives: To date it is not clear to which extent a clinical, or even a subclinical, sexual dysfunction in the female partner might associate with erectile dysfunction (ED) in the male partner. The present study is aimed at the assessment of clinical features of ED associated with relational disturbances.Methods: In a consecutive series of 1140 male subjects reporting a stable couple relationship we evaluated the impact of relational factors, as assess...

Introduction: While the association of Klinefelter’s syndrome (KS) with infertility is well known, very few investigations have evaluated the prevalence of sexual dysfunction in KS. The aim of the present study is to systematically analyse the prevalence of KS in a consecutive series of adult male patients consulting for sexual problems and to investigate its specific correlates.Methods: Among a consecutive series of 1386 patients (mean age 48.9&#17...