Endocrine Abstracts

Introduction: Parathyroid surgical therapy differs because the glands are small and of variable number and location. Although localization studies have improved greatly, we may not reliably determine the number and location of all diseased glands preoperatively. Ultrasonography (US) is the most widely used imaging method. In this study, we aimed to demonstrate how the surgical outcomes change when the surgeon accompanies the endocrinologist during preoperative ultrasonography ...

Introduction: Parathyroid carcinoma (PC) is a rare endocrine malignancy which accounts for 0.005% of all cancers and less than 1% of primary hyperparathyroidism cases. This uncommon tumor usually occurs during the fifth decade of life, with equal frequency in both sexes, and has an indolent but progressive course. It’s frequently symptomatic and patients may have high values of serum calcium and parathyroid hormone (PTH) with a palpable cervical mass. PC generally occurs ...

Introduction: Prolactinomas are the most common hormonally active pituitary tumors that account for 40–60% of all pituitary adenomas and are usually successfully treated with dopamine agonists. Surgery or radiotherapy is reserved for drug intolerance/resistance or in neuro-ophthalmological emergencies. We present a patient with refractory microprolactinoma with empty sella treated by transsphenoidal surgery.Case: 42-year-old female patient admitted ...

Introduction: Premature ovarian failure (POF) is a disorder associated with female infertility, and it affects approximately 1% of women under the age of 40 year. It is considered a multifactorial, heterogeneous condition, for which the exact underlying cause remains unclear. Associations with autoimmune diseases, environmental factors and genetic causes have been described. Herein we presented a case with POF who regained fertility after the treatment of Graves disease.<p...

Introduction: Tolosa Hunt syndrome (THS) is described as unilateral orbital pain associated with paresis of one or more of the third, fourth and/or sixth cranial nerves caused by a granulomatous inflammation in the cavernous sinus, superior orbital fissure or orbit. Pituitary gland is rarely involved in this syndrome. Herein we represented a case with hypophysitis with Tolosa Hunt who was operated with the suspicion of pituitary adenoma.Case: A 63-year-o...

Background: The characteristics of multifocal PTC remain controversial. Surgical approach to multifocal tumor changes between centers. In cases that the initial procedure was lobectomy, most clinicians would suggest for completion thyroidectomy since the risk of PTC in the contralateral lobe is significant. This study aimed to evaluate the incidence of bilateral involvement, predictive factors for bilaterality and whether or not bilaterality was related with more aggressive hi...

Background: Differential diagnosis of a thyroid nodule is difficult if it is a follicular lesion. Follicular lesions include follicular adenoma (FA) or a malign neoplasm (follicular cancer (FC) or follicular variant of papillary thyroid carcinoma (FVPTC)). Cytology can’t separate benign from malignant condition in follicular lesions. Differential diagnosis is important because patients often undergo less than ideal interventions, such as a total thyroidectomy for a benign...

Objective: Polycystic ovary syndrome (PCOS) is a complex endocrinopathy affecting 5–10% of women in reproductive period. Our goal is to determine which symptoms and findings are the most common in Turkish adolescents with PCOS.Material and method: Ninety three adolescents (15–19 years old) who admitted to our outpatient clinic with at least one of the complaints (acne, obesity, menstrual irregularities and hirsutism) were enrolled in the study....

Introduction: Mitochondrial diseases usually occur by mutations of mitochondrial or nuclear DNA. Mitochondrial cytopathy is a disease affecting many systems including endocrine system. We present a case diagnosed as mitochondrial myopathy previously accompanying multiple endocrinological pathologies.Case: Fifty-two years old female patient admitted in another center with a complaint of drooping of upper eyelids 25 years ago. Acetylcholine receptor antibo...

Introduction: Primary hyperparatyhyroidism (PHPT) is usually caused by single or multiple adenomas and cancer is rare accounting for <1% of all presentations. The presence of certain cytological and architectural features such as adherence to adjacent organs, a solid growth pattern, broad bands of fibrosis, cytological atypia, and an irregular growth contour do not indicate malignancy but are recognised as atypical features encountered more commonly in malignant than benig...