Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep343 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Irisin plasma level is connected with the android adipose tissue deposit

Pukajlo Katarzyna , Kolackov Katarzyna , Laczmanski Lukasz , Kuliczkowska-Plaksej Justyna , Bolanowski Marek , Milewicz Andrzej , Daroszewski Jacek

Irisin (Ir), a recently identified adipomyokine, cleaved and secreted to the circulation from the FNDC5 protein in response to physical activity and some environmental conditions has been postulated to induces the differentiation of a subset of white adipocytes into brown fat and mediates the beneficial effects of exercise on metabolic homeostasis. Polycystic ovary syndrome (PCOS) – one of the most frequent endocrinopathies affecting women of child-bearing age is associat...

ea0037ep344 | Diabetes (pathiophysiology & epitemiology) | ECE2015

The GH treatment results in the increase of irisin concentration in plasma

Wikiera Beata , Pukajlo Katarzyna , Laczmanski Lukasz , Sloka Natalia , Basiak Aleksander , Bolanowski Marek , Noczynska Anna , Daroszewski Jacek

Brown adipose tissue metabolism is of remarkable pathophysiological interest, because it could be a target for future therapies for obesity and metabolic syndrome. Irisin (Ir), recently identified novel adipomyokine is essential in a white-to-brown fatty tissue transdifferentiation, and mediates some of the positive influences on metabolic disorders through increase of energy expenditure. The exact regulation of Ir secretion and action is unknown but significant positive assoc...

ea0035p303 | Clinical case reports Thyroid/Others | ECE2014

A patient with lung ectopic parathyroid coexistent with primary hyperparathyroidism and end-stage renal diseases

Kowalska Beata , Lomna-Bogdanov Elzbieta , Pukajlo Katarzyna , Kaluzny Marcin , Jedrzejuk Diana , Doskocz Krzysztof

We report the case of 57-year-old man with end-stage renal disease, primary hyperparathyroidism and after an surgery of upper parathyroid glands with ectopic parathyroid localized in lung. Patient was directed to our hospital to perform diagnostics on hyperparathyroidism. Two years earlier (2011) patient was hospitalized because of weakness and weight loss, and was diagnosed with primary hyperparathyroidism. In 2012 he underwent the bilateral parathyroidectomy of upper glands ...

ea0035p758 | Obesity | ECE2014

Irisin plasma concentration in PCOS and healthy subjects is related to body adipose content

Pukajlo Katarzyna , Kolackov Katarzyna , Laczmanski Lukasz , Kuliczkowska-Plaksej Justyna , Lenarcik-Kabza Agnieszka , Milewicz Andrzej , Daroszewski Jacek

Polycystic ovary syndrome (PCOS) is a common endocrine abnormality connected not only with reproductive problems but also with impaired energy homeostasis leading to metabolic disorders including metabolic syndrome. Irisin (Ir), recently identified novel myokine, has been proposed to mediate some of the positive influence on metabolic disorders. The aim of our study was to search the relationship between Ir plasma concentration in PCOS in the context of metabolic disturbances....

ea0035p372 | Diabetes (epidemiology, pathophysiology) | ECE2014

Branched-chain and aromatic amino acid plasma concentration as a markers of metabolic syndrome

Daroszewski Jacek , Rybka Jacek , Pukajlo Katarzyna , Bolanowski Marek , Stankiewicz-Olczyk Joanna , Mierzchala Magdalena , Rybka Wojciech , Gamian Andrzej

Results of metabolomic studies showed the relation of branched-chain amino acids (BCAA) and aromatic amino acids (AAA) with metabolic disorders.Basing on this observation we assessed amino acid profile in 286 professionally active men (aged 36–60 years). 141 of them met the criteria of metabolic syndrome (MS) and remaining 142 served as controls.Quantitative analysis of BCAA (leucine-LEU, valine-VAL, isoleucine- ILE) and AAA (...