Endocrine Abstracts

Thyrotropin-secreting pituitary adenomas (TSHomas) are rare functioning pituitary adenomas, accounting for less than 1%. They commonly present as macroadenomas with symptoms of hyperthyroidism. Though surgery is the first line therapy, cure is achieved in only 30–40%, with high rate of post-surgical hypopituitarism. We propose somatostatin analogs having a new role in the management. We report a case of 73 years-old man with a 6-month history of palpitations and progress...

Background: Pituitary adenomas (PAs) in the elderly, defined as people older than 65 years, represent less than 10% of all PAs. Because of increasing life expectancy and improving health care, diagnosis PAs in this age group is increasing with time. Age-related changes and associated diseases may significantly modify the clinical presentation in these patients, delaying the diagnosis of PAs.Objective: To analyse the clinical features of PAs in elderly pa...

Background and objective: The incidence of differentiated thyroid carcinoma (DTC) is increasing worldwide. Radioiodine (RAI) ablation is one of the main elements in the therapy of DTC after surgical removal of the gland. This study aims to compare the use of I131 in a Spanish Cohort of DTC before and after the American Thyroid Association (ATA) 2009 guidelines.Patients and methods: The Cadit-CAM study was designed to evaluate retrospectively characterist...

Introduction: Hypophysitis is a rare disease. Lately, it is more frequent due to the use of Inmune Check Point Inhibitor (ICPIs). Ipilimumab or combo Ipilimumab + Nivolumab are the main cause. Agree with literature, 17-18% of the patients with these drugs suffer from. By contrast, with Idiopatic Autoimmune Hypophysitis and Lymphocytic Hypophysitis, this type of hypophysitis occurs in sixties men. Autoinmunity mechanism is known, but precise pathophysiology is unclear <p cl...

Background and objective: Papillary thyroid microcarcinoma (PTMC) is recognized as a separate entity by the World Health Organization. Biological behaviour and clinical outcomes of PTMC are heterogenous. Presence of lymph node metastases (LNM) in this group of patients increases the risk of recurrence and makes optimal management in PTMC controversial (observation, lobectomy with or without preventive central ipsilateral dissection). The aim of this study was to describe risk ...

Background and objective: Incidence of differentiated thyroid cancer (DTC) is increasing but not its mortality. Knowing recurrence factors is essential to plan its treatment. Recurrence related factors in our area were reviewed and compared with ATA risk stratification system.Patients and Methods: The Cadit-CAM study was designed to evaluate characteristics of patients diagnosed of DTC in Castilla La Mancha, a region in the central part of Spain, during ...

Background and objective: The AJCC-TNM system is optimized to predict survival in patients with cancer. Since January 2018, the new eighth edition of this staging system will be used to classify patients diagnosed of differentiated thyroid carcinoma (DTC). This study aims to compare the seventh and eighth editions of the AJCC-TNM system in a Spanish Cohort of DTC.Patients and Methods: The Cadit-CAM study was designed to evaluate characteristics of patien...