Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep835 | Pituitary and Neuroendocrinology | ECE2023

Pituitary metastasis from colon cancer in a young patient

Ferreira Ana , Dias Angela , Raimundo Luisa

Introduction: Pituitary metastases account for approximately 1% of pituitary lesions, most frequently originating from lung or breast cancer. We describe a case of a pituitary metastasis from colon cancer, a rare origin.Case report: a 36 year-old male, previously healthy, came to the emergency department for new onset jaundice and fever. He also had headaches for the last 3 months, and for the last month diplopia, left palpebral ptosis and low libido. Ph...

ea0020p533 | Paediatric Endocrinology | ECE2009

Prevalence of autoimmune thyroiditis in children with diabetes mellitus

Veloza Andreia , Coelho Catarina , Manita Isabel , Cordeiro Maria , Passos Dolores , Raimundo Luisa , Portugal Jorge

Introduction: Type 1 diabetes mellitus (DM1) is frequently associated with other autoimmune diseases. Among children and adolescents, thyroid disease is the most common autoimmune endocrinopathy. The possibility of occult thyroid disease should be considered at diagnosis and when a patient is assessed at the annual review.Objective: The aim of our study was to determine the prevalence of autoimmune thyroiditis among children and adolescents with type 1 d...

ea0014p424 | (1) | ECE2007

Juvenile osteoporosis in untreated GH-deficient patient – is treatment with GH replacement indicated? A clinical case report

Coelho Catarina , Saraiva Catarina , Manita Isabel , Velosa Andreia , Passos Dolores , Carlos Maria , Raimundo Luisa , Portugal Jorge

Treatment for osteoporosis in children/adolescents is extremely important not only to improve bone quality but also because, if left untreated, could lead to severe and precocious loss of bone mass. Studies in growth hormone (GH) deficient adults, in turn, have shown that treatment with GH produce bone mass gain and improve the occurrence of both bone formation and reabsorption.The authors present the following case report of a 16 year old Caucasian fema...

ea0037ep939 | Thyroid (non-cancer) | ECE2015

Seasonality in paediatric Graves' disease compared to the general population: impact of month of birth: a national study

da Silva Tiago Nunes , Pereira Bernardo Dias , Luiz Henrique Vara , Matos Ana Catarina , Cordeiro Maria Carlos , Raimundo Luisa , Portugal Jorge

Paediatric Graves’ disease (PGD) is an uncommon autoimmune disorder with a multifactorial origin. Although, in some autoimmune endocrinophaties the seasonality of month of birth (MOB) distribution differed from the general population, this association has not been study in PGD. The aim of this work was to analyse the impact of seasonality of MOB on PGD incidence in Portugal.In 2013, the Portuguese Paediatric Society of Diabetes and Endocrinology und...

ea0081p741 | Thyroid | ECE2022

Efficacy of radioactive iodine treatment in Graves Disease using a calculated 131I dose and predictive factors of success in a Portuguese cohort

Franco Sara , Teixeira Ferreira Rita , Cardoso Ferreira Ines , Quitalo Ana , Barbosa David , Manuel Costa Maria , Vara Luiz Henrique , Raimundo Luisa , Isabel Santos Ana

Aim: Dose corrected for thyroid gland size is one of the methods used to determine radioactive iodine (RAI) activity for patients with Graves disease (GD). This study was aimed to investigate the real-world success rate of this method and the predictors of success after first treatment.Methods: This is a retrospective study of 80 patients with GD treated between 2014 and 2020 in a tertiary referral hospital in Almada, Portugal. The successful group was d...

ea0037gp.27.07 | Thyroid – hyperthyroidism and treatment | ECE2015

Plasmapheresis in thyroid storm caused by exogenous thyroid hormone intake: a case series

da Silva Tiago Nunes , Pereira Bernardo Dias , Luiz Henrique Vara , Macau Ricardo , Matos Ana Catarina , Manita Isabel , Bravo Pedro , Cordeiro Maria Carlos , Raimundo Luisa , Portugal Jorge

Thyroid storm (TS) is one extreme of a continuum beginning with thyrotoxicosis. It’s rarely caused by exogenous thyroid hormone intake (ETHI). Aggressive medical therapy is the cornerstone of treatment; nevertheless, it might not be sufficient. Plasmapheresis is an extracorporeal technique that can rapidly lower thyroid hormone levels. The aim of this study was to assess the efficacy of plasmapheresis in TS secondary to ETHI. We evaluated retrospectively all TS cases (Bur...

ea0035p58 | Adrenal Medulla | ECE2014

Pheochromocytomas and paragangliomas: association between tumor size and measurements of metanephrines and catecholamines

Luiz Henrique Vara , Silva Tiago Nunes da , Pereira Bernardo Dias , Veloza Andreia , Matos Ana Catarina , Manita Isabel , Cordeiro Maria Carlos , Raimundo Luisa , Portugal Jorge

Introduction: Pheochromocytomas (PHEO) and paragangliomas (PGL) are rare catecholamine-secreting tumors. Some authors proposed that there is a positive linear relationship between tumor size and measurements of metanephrines and an absence of association with catecholamine levels.Objectives: To review and characterize patients diagnosed with PHEO and PGL in Garcia de Orta Hospital. To determine the relationship between tumor size and measurements of urin...

ea0070ep269 | Endocrine-related Cancer | ECE2020

Multiple endocrine neoplasia: A case series of 7 families

Duarte Vitória , Ivo Catarina , Veríssimo David , Marcelino Mafalda , Vara Luiz Henrique , Franco Sara , Bastos Filipa , Manita Isabel , Raimundo Luisa , Portugal Jorge

Introduction: Multiple endocrine neoplasia (MEN) is a rare genetic syndrome characterized by occurrence of tumors involving two or more endocrine glands. Four types are described: MEN1, MEN2, MEN3 and the recently identi&#-1279;ed MEN4. Due to the complexity of the syndromes, it is difficult to manage these patients. Our objective was to describe the clinical features of individuals from 7 families with a diagnosis of MEN1 or MEN2 and identify current challenges in clinical pr...

ea0032p1022 | Thyroid (non-cancer) | ECE2013

IgG4-related Hashimoto's thyroiditis: an emerging variant of a well known disease

Luiz Henrique , Goncalves Diogo , Pereira Bernardo , da Silva Tiago , Veloza Andreia , Matos Catarina , Manita Isabel , Cordeiro Maria , Raimundo Luisa , Oliveira Ana , Brito Maria , Portugal Jorge

Introduction: IgG4-related Hashimoto’s thyroiditis (HT) is a very recently reported entity, characterized by thyroid inflammation rich in IgG4-positive plasma cells associated with marked fibrosis. It may be part of the systemic IgG4-related sclerosing disease and is associated with younger age, lower female:male ratio, higher levels of thyroid autoantibodies, low echogenicity on ultrasound (US), rapid progress requiring surgery and more subclinical hypothyroidism, when c...

ea0049ep887 | Growth hormone IGF axis - basic | ECE2017

Somatropin treatment Supported by NHS: characterization of submitted patients – 2006 to 2016

Bastos Margarida , Mirante Alice , Afonso Caldas , Vasconcelos Carlos , Bacelar Conceicao , Pereira Conceicao , Lopes Lurdes , Fonseca Marcelo , Serra-Caetano Joana , Patricio Miguel , Esteves Cesar Marques , Ferreira Florbela , Braganca Graciete , Raimundo Luisa , Matos Lurdes , Sampaio Lurdes , Fontoura Manuel , Borges Teresa

Introduction: In our country somatropin treatment is supported by the National Health Service. A National Committee (CNNHC) rules and analysis the submission papers of patients with: isolated/multiple somatotropin deficiency (STD), short stature in: renal chronic disease (DRC), small for gestational age (SGA), Turner syndrome (TS) and Prader Willi syndrome (PWS). In adults only isolated somatropin deficiency diagnosed in childhood.Aims: To analyze the ch...