Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp29 | Diabetes and Cardiovascular Disease | ECE2019

Systematic screening of masked hypertension in normotensive type 2 diabetic patients

Ghorbel Dorra , Hadjkacem Faten , Triki Faten , Mnif Mouna , Charfi Nadia , Rekik Nabila , Kammoun Samir , Abid Mohamed

Introduction: Masked hypertension (MH) is a relatively recent description leading to a similar cardiovascular risk as permanent hypertension. Masked hypertension is more common among diabetic patients.Methods: This was a case-control study. We performed 24-hour ambulatory BP in 53 type 2 diabetic patients normotensive in clinical measurement. We compared both Masked Hypertension and Normotensive groups according to clinical/laboratory parameters and targ...

ea0063p1058 | Pituitary and Neuroendocrinology 3 | ECE2019

Pituitary apoplexy: diagnosis, management and outcome in 44 patients

Gargouri Imen , Hadjkacem Faten , Mnif Mouna , Walha Mohamed , Rekik Nabila , Charfi Nadia , Ayadi Fatma , Abid Mohamed

Introduction: Pituitary apoplexy (PA) is a rare incident defined by the occurrence of necrosis and/or haemorrhage of the pituitary gland. PA is a clinical syndrome characterized by the sudden onset of headache, vomiting, visual impairment and decreased consciousness in some cases. The objectives of our study are to describe its clinical, biological and imaging features as well as the management of PA in the region of Sfax.Patients and methods: It is a re...

ea0063ep20 | Adrenal and Neuroendocrine Tumours | ECE2019

Adrenocortical carcinoma: epidemiological, clinical and paraclinical profile: about 4 cases

Mnif Fatma , Elleuch Mouna , Sahnoun Randa , Saafi Wiem , Mnif Mouna , Charfi Nedia , Rekik Nabila , Abud Mohamed

Introduction: The adrenocortical carcinoma (ACC) is a primary malignant tumor developed in depends of the adrenal cortex, defined by a Weiss score ≥3. Despite the therapeutic progress, its prognosis is still severe.Patients and methods: This retrospective descriptive study evaluated 4 patients with adrenal corticosteroid followed in the endocrinology department of Sfax - Tunisia between 2010 and 2018.Results: There were 3 wom...

ea0063ep102 | Pituitary and Neuroendocrinology | ECE2019

Thyrotropin-producing pituitary adenoma: 3 case reports

Hadjkacem Faten , Gargouri Imen , Bensalah Dhouha , Neifar Manel , Boujelben Khouloud , Charfi Nadia , Rekik Nabila , Abid Mohamed

Introduction: Thyrotropin-secreting pituitary adenomas represent less than 1% of all pituitary adenomas. Usually, patients present mild or moderate signs of hyperthyroidism and Hormonal evaluation shows increased free thyroid hormone concentration with detectable, normal or increased serum thyrotropin (TSH) level. Herein we report three cases of thyrotropin adenomas with particular clinical and biological features.Observations: Three patients, aged 25 38...

ea0049ep335 | Clinical case reports - Thyroid/Others | ECE2017

An usual cause of post operative hypocalcemia

Mnif Fatma , Safi Wajdi , Rekik Nabila , Mrabet Houcem , Elfekih Hamza , Charfi Nadia , Mnif Mouna , Abid Mohammed

Introduction: The otorhinolaryngologist can be confronted to multiple surprises after a thyroid surgeryCase description: We report the case of a 48 year-old woman admitted with post operative hypocalcaemia (after thyroidectomy?). The patient has a history of hypothyroidism since 5 years. She then presented a cervical swelling. The ultra-sound confirmed the presence of a suspicious thyroid nodule measuring 4 cm. A thyroidectomy was then conducted. Post op...

ea0056p1088 | Thyroid (non-cancer) | ECE2018

Dysthyroidism and chromosomal aberrations

Ghorbel Dorra , Mnif Fatma , Chebbi Donia , Salah Dhouha Ben , Rekik Nabila , Abid Mohamed

Introduction: Dysthyroidism is not uncommon during chromosomal aberrations. The objective of this work is to study the characteristics of this association at the epidemiological and clinical levels.Methods: This is a retrospective study of 27 cases of patients with trisomy 21 chromosomal abnormalities (6 cases), klinefelter syndrome (4 cases) and Turner syndrome (17 cases) genetically confirmed, collected at endocrinology service at Sfax University Hospi...

ea0081ep958 | Thyroid | ECE2022

Immunogenetic aspects of polyglandular autoimmune syndrome

Mnif Fatma , Soomauroo Siddiqa , Belabed Wafa , Fourati Hajer , Missaoui Abdelmouhaymen , Salah Dhoha Ben , Elleuch Mouna , Rekik Nabila , Abid Mohamed

Introduction: Polyglandular autoimmune syndrome (PAS) are uncommon constellations of autoimmune diseases characterized by the occurrence of two or more auto-immune endocrine diseases in the same individual.Patients and methods: It is a case-control study about 108 cases for 120 healthy subjects recruited as the control group. We aimed to study the polymorphism of the HLA class-II genes of patients compared to that of healthy subjects so as to identify th...

ea0063p834 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Familial multiple endocrine neoplasia type 1 revealed by a maxillary swelling

Salah Dhouha Ben , Gargouri Imen , Mnif Fatma , Elleuch Mouna , Charfi Nadia , Mnif Mouna , Rekik Nabila , Abid Mohamed

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant disorder caused by mutations in the MEN1 tumor suppressor gene and is characterized clinically by tumors in two or more endocrine glands, such as the pituitary gland, parathyroid glands or pancreatic islets. We describe an atypical presentation of familial hyperparathyroidism evoking the diagnosis of MEN1 in the first place.Observations: We report a three-member family....

ea0063p1097 | Pituitary and Neuroendocrinology 3 | ECE2019

Predictive factor of hypopituitarism in prolactinoma

Elleuch Mouna , Loukil Fatma , Mnif Fatma , Salah Dhouha Ben , Hadjkacem Faten , Mnif Mouna , Charfi Nedia , Rekik Nabila , Abid Mohamed

Intoduction: Pitiutary tumor is considered as the first etiology responsable of secondary hypopituitarism. Hypogonadotropic hypogonadism is the most commonly reported lesion.Meterials and methods: It is a retrospective study including 77 cases of prolactinoma. The data collection was done over 17 years, between 2000 and 2017.Results: Gonadotropic deficiency was confirmed in 48 patients (63.6%). A significant negative correlation wa...

ea0063ep103 | Pituitary and Neuroendocrinology | ECE2019

Non-functional pituitary adenoma

Hadjkacem Faten , Ghariani Imen , Gargouri Imen , Mnif Mouna , Rekik Nabila , Njeh Hanen , Mahfoudh Khaireddine Ben , Abid Mohamed

Introduction: The non-functional pituitary adenoma (NFPA) is a benign tumor, which has a progressive development but it is a severe tumor by its neuro-ophthalmological and endocrine repercussions.Patients and methods: It is about a descriptive and retrospective study conducted in 35 patients collected in the endocrinology department of Sfax between January 2000 and December 2017. The diagnosis of NFPA was based on the presence of pituitary adenoma on hyp...