Searchable abstracts of presentations at key conferences in endocrinology

ea0016p453 | Neuroendocrinology | ECE2008

Endocrinopathies with langerhans cell histiocytosis (LCH): nine cases

Yarman Sema , Mert Meral , Salman Serpil , Tanakol Refik , Alagol Faruk

LCH is a rare proliferative histiocytic disorder, and it can infiltrate virtually any site in the body. Diabetes incipidus (DI) is the most common abnormality when there is involvement of the hypothalamic-pituitary axis (HPA). We have evaluated the anterior pituitary function and their responses to treatment in 9 patients (5M/4F; range 19–60 years) with proven LCH and DI. Endocrine evaluations consisted of clinical history, basal (GH, IGF-1, fT4, TSH, PRL, cortisol, LH, F...

ea0016p82 | Bone and calcium | ECE2008

Primary hyperparathyroidism during pregnancy: a case report

Dogru Hulya , Bicakci Ercan , Salman Serpil , Yarman Sema , Tanakol Refik , Boztepe Harika , Alagol Faruk

Primary hyperparathyroidism (PHP) during pregnancy is a very rare event that increases maternal and fetal morbidity and mortality. Complications during pregnancy or neonatal period have included spontaneous abortion, stillbirth, neonatal death, neonatal tetany.Management of maternal PHP diagnosed during pregnancy should be based on the patients’ symptoms and severity of the disease. Hyperparathyroidism characterized by progressive symptoms should be...

ea0016p303 | Endocrine tumours | ECE2008

Cushings' syndrome due to ectopic ACTH secretion: four cases

Yarman Sema , Mert Meral , Salman Serpil , Tanakol Refik , Boztepe Harika , Alagol Faruk

Ectopic ACTH syndrome (EAS) occurs in around 10% of all cases with ACTH-dependent hypercortisolism. The mean age of clinical presentation varies from 45 to 50 years, and most of them caused by intrathoracic neoplasm, and recognition of the disorder may be delay. Subsequently, it may be difficult to locate the ACTH source and manage the patients’ hypercortisolism. We present our patients with EAS from 2000 to 2007. Four patients, aged 15–43 years, two females and two ...

ea0020p238 | Bone/Calcium | ECE2009

Evaluation of the association between bone turnover markers and OPG/sRANK-L levels in relation with the changes of thyroid function in women with thyroid cancer

Salman Serpil , Aral Ferihan , Boztepe Harika , Colak Nese , Omer Beyhan , Tanakol Refik , Alagol Faruk , Kabut-Uzum Ayse

Aim: Thyroid hormones play an important role in bone remodeling. The aim of the study was to evaluate the changes of bone markers and osteoprotegerin (OPG)/sRANK-L levels during follow-up in a group of patients with thyroid cancer.Material and methods: Twenty euthyroid women with the diagnosis of differentiated thyroid cancer were enrolled to the study (39.25±13.46 years, 6 postmenopausal) before thyroidectomy. Samples were collected before the oper...