Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp21 | Adrenal (2) | ECE2016

Clinical characteristics and tumour size evolution in patients with bilateral adrenal tumours

Galoiu Simona , Pena Raluca , Trifanescu Raluca , Niculescu Dan Alexandru , Dumitrascu Anda , Caragheorgheopol Andra , Iordachescu Carmen , Poiana Catalina

10% of patients with adrenal tumours have bilateral lesion.Objective: To evaluate clinical, imagistic and hormonal characteristics of bilateral adrenal tumours.Design and mehods: Retrospective series of 150 consecutive patients (104F, 46M) with bilateral adrenal tumours with maximal diameter of at least 1 cm, evaluated from 2001 to 2015 in a tertiary endocrinology clinic with clinical, hormonal and imagistic methods.<p class="a...

ea0022p853 | Thyroid | ECE2010

Marked sensitivity of pituitary feedback to levothyroxine in asymptomatic primary autoimmune hypothyroidism

Trifanescu Raluca-Alexandra , Coculescu Mihail

Background: Few cases of hypersensitivity of thyroid–pituitary feedback in hypothyroid children were reported.Aim: To present a family with asymptomatic, severe biochemical primary autoimmune hypothyroidism who showed a marked sensitivity of pituitary feedback to levothyroxine treatment.Methods: TSH was measured by 3rd generation immunoassay kit.Case report: R.G, woman, aged 22, presented for asymptomati...

ea0037ep289 | Calcium and Vitamin D metabolism | ECE2015

Glucocorticoid induced osteoporosis: can we do more to prevent it?

Cristina Plaisanu , Vasilia Iorgoveanu , Raluca Trifanescu

Introduction: Osteoporosis is a well-known and extremely debated side effect of glucocorticoid therapy being able to generate vertebral fractures even at low doses. Our study highlights the need for better prevention through improved doctor-patient communication and correct implementation of available screening tools.Methods: Since August–December 2014 we distributed to 85 rheumatic patients a self-compiled questionnaire. We recorded patient data an...

ea0020p88 | Thyroid | ECE2009

What is the outcome of combined therapies in amiodarone-induced thyrotoxicosis?

Trifanescu Raluca-Alexandra , Ursu Horea , Purice Mariana

Objective: To assess the outcome of medical and ablative therapies in amiodarone-induced thyrotoxicosis (AIT).Subjects and methods: Seventy patients (32 M/38 F, aged 59.7±1.4 years) with AIT (24-type 1, 20-type 2 and 26-mixed forms) were followed-up 13.4±2.3 months. TSH was measured by immunoradiometric assay, TT3 and TT4 by chemiluminescence.Results: Antithyroid drugs (ATD) were used as single thera...

ea0044p228 | Reproduction | SFEBES2016

Causes of primary amenorrhea in women evaluated in an academic center of adult endocrinology

Gheorghiu Monica Livia , Cucu Constantin , Trifanescu Raluca Alexandra , Badiu Corin

Introduction: Primary amenorrhea is defined as the absence of menses at age 15 years in the presence of normal growth and secondary sexual characteristics, or at 13 years, if there is no breast development. We retrospectively assessed the causes of primary amenorrhea in a series from an academic center of adult endocrinology.Patients and methods: We retrieved data from the files of 111 consecutive patients with primary amenorrhea evaluated in our center ...

ea0038p162 | Neoplasia, cancer and late effects | SFEBES2015

Outcome of insulinomas diagnosed in a tertiary endocrine centre

Trifanescu Raluca , Baciu Ionela , Gheorghiu Monica , Dumitrascu Anda , Poiana Catalina

Background: Insulinomas, the most common functional neuroendocrine tumours of the pancreas, are usually sporadic, benign and solitary.Aims: To assess biochemical data, localisation and treatment outcome of insulinomas diagnosed in a tertiary endocrine centre.Patients and methods: Twenty-five patients (14 F/11 M), aged 49.1±14.1 years, diagnosed with insulinoma in a Neuroendocrine Tumours centre between 2000 and 2014 were retro...

ea0035p92 | Bone and Osteoporosis | ECE2014

Increased osteoporotic fractures' risk in elderly patients with lower sodium levels

Trifanescu Raluca , Carsote Mara , Soare Dan , Poiana Catalina

Background: Low serum sodium levels were associated both in experimental studies and in clinical practice with increased prevalence of osteoporosis, due to decreased bone mineralization and increased osteoclastic activity. On the other hand, hyponatremia – independent of osteoporosis – is associated with fracture occurrence.Objectives: To assess the relationship between serum sodium levels and osteoporotic fractures.Patie...

ea0032p326 | Clinical case reports - Thyroid / Others | ECE2013

Radiation-induced primary hypothyroidism in patients with head and neck cancer

Trifanescu Raluca , Ion Oana , Carsote Mara , Poiana Catalina

Background: Hypothyroidism is a frequent side effect of external radiotherapy of the cervical region for head and neck cancer. Up to 33% of irradiated patients developed primary hypothyroidism within 2 years after radiation therapy. The risk of hypothyroidism increases with radiation dose.Patients and methods: Four patients (2M/2F), aged 53.3±13.9 years, resident both in iodine sufficient (n=2) and iodine deficient areas (n=2), wer...

ea0016p235 | Diabetes and cardiovascular diseases | ECE2008

Cumulative incidence, timing and risk factors for thyroid dysfunction in 144 Romanian patients treated with amiodarone

Trifanescu Raluca-Alexandra , Fica Simona , Ion Oana-Gabriela , Coculescu Mihail

Aim: To assess cumulative incidence and risk factors for amiodarone-induced thyroid dysfunction (AITD) in a large cohort of Romanian subjects.Subjects and methods: One hundred and forty-four patients (59 M/85 F), mean age 61.4±0.9 years, treated 2.4±0.2 years with amiodarone were assessed for TSH, TT3, TT4 (immunoradiometric assays) and FT4, TPO Ab (microenzymatic immunoassays). Thirty-three patients were reside...

ea0056p84 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2018

Metabolic and hormonal profile in primary aldosteronism as compared with essential hypertension

Trifanescu Raluca , Smarandoiu Alexandra , Caragheorgheopol Andra , Iordachescu Carmen , Poiana Catalina

Background: Primary aldosteronism is associated with increased vascular mortality and morbidity.Aims: We aimed to assess metabolic and hormonal profile differences in patients with primary aldosteronism (PA) compared with patients with essential hypertension (EH).Patients and methods: Thirty-one patients (11 M/20 F) with primary aldosteronism, aged 46.2±12.9 years and 64 patients (24 M/40 F) with essential hypertension, aged 4...