Searchable abstracts of presentations at key conferences in endocrinology

ea0032p1096 | Thyroid cancer | ECE2013

Radioactive iodine therapy in papillary thyroid carcinomas staged as T1

Marques Pedro , Macedo Daniel , Pereira Joana , Vieira Margarida , Leite Valeriano , Bugalho Maria

Introduction: 131I therapy in patients with papillary thyroid carcinomas (PTC) ≤2 cm and without extrathyroidal extension (T1) depends on multifactorial analysis: age, multifocality, histological criteria, lymph node or systemic metastasis. The study purposes were analyze PTC-T1 and compare the groups treated only with surgery vs combined therapy (surgery and 131I).Methods: Retrospective analysis of clinical files of PTC-T1 pa...

ea0063p242 | Pituitary and Neuroendocrinology 1 | ECE2019

Pituitary tumors diagnosed in octogenarians – clinical implications

Cunha Nelson , Gomes Leonor , Paiva Isabel , Fadiga Lucia , Catarino Diana , Silva Diana , Guiomar Joana , Vieira Ines , Lavrador Mariana , Bastos Margarida

Introduction: The aging population brought new challenges in several diseases. Pituitary tumors are usually not related with elderly, although the rise in life expectancy has allowed its diagnosis in unusual age groups.Aim: To describe the pituitary tumors diagnosed in patients with age ≥ 80 yearsMethods: Retrospective observational study which included 23 patients with pituitary tumors with age ≥ 80 years observed in c...

ea0049ep1356 | Thyroid (non-cancer) | ECE2017

TSH receptor stimulating immunoglobulins – performance of an automated immunoassay

Tavares Patricia , Machado Catarina , Pedroso Jose Carlos , Vieira Joana , Rocha Gustavo , Monteiro Sara , Sousa Ana Margarida , Rodrigues Pedro , Lira Agostinho , Oliveira Maria Joao

Introduction: Graves’ disease (GD) hyperthyroidism is caused by autoantibodies against TSH receptor (TRAb). Three varieties of TRAb are now recognized: stimulating (TSI), blocking and neutral antibodies. Current TRAb immunoassays detect and quantify serum immunoglobulins that interact with the TSH receptor but without discriminating their function. An automated immunoassay for the detection and quantification of TSI is available.Objective: Our study...

ea0070ep21 | Adrenal and Cardiovascular Endocrinology | ECE2020

Singularities of the undertreatment of congenital adrenal hyperplasia in adults

Lavrador Mariana , Lages Adriana , Catarino Diana , Fadiga Lúcia , Alexandra Festas Silva Diana , Reis Guiomar Joana , Vieira Inês , Barros Luísa , Paiva Isabel

Introduction: Congenital Adrenal Hyperplasia (CAH) results from enzymatic defects caused by autossomal recessive hereditary mutations characterized by deficient cortisol synthesis and, in most cases, increased androgen synthesis. 90–95% of the cases are originated by deficits in 21-hydroxylase and, in about 75% of the cases, there is evidence of mineralocorticoid deficiency.Case report: A 37-year-old patient was referred to an Endocrinology departm...

ea0070ep43 | Adrenal and Cardiovascular Endocrinology | ECE2020

Pericarditis complicated with cardiac tamponade and Addison disease – A case report

Lavrador Mariana , Cardoso Luís , Catarino Diana , Fadiga Lúcia , Silva Diana , Guiomar Joana , Vieira Inês , Araújo Bárbara , Araújo Cátia , Barros Luísa , Paiva Isabel

Introduction: Addison Disease is a rare condition with an estimated incidence in the developed world of 0.8 cases per 100 000 population. It is associated with relevant morbidity and mortality rates, but once the diagnosis is made it can be easily managed. When Addison Disease is associated with other autoimmune diseases, the diagnosis of polyglandular autoimmune syndrome can be set. The recognition of symptoms and signs can be challenging and clinicians should be aware of aty...

ea0022p120 | Bone/Calcium | ECE2010

Estradiol and testosterone levels in diabetic type 2 men with low bone density and osteoporosis

Mascarenhas Mario Rui , Barbosa Ana Paula , Nobre Ema , Goncalves Ana , Simoes Vera , Camolas Jose , Carvalho Maria Raquel , Ferreira Joana , Vieira Joao , Pinto David Santos , Bicho Manuel , do Carmo Isabel

Osteoporosis and diabetes mellitus type 2 (DM2) have severe health consequences, with high morbidity and mortality risks.Aims: To study the differences of the sex steroid hormones levels and the free androgen index (FAI) in DM2 men with low BMD and osteoporosis and their relationships with BMD.Materials and methods: In 317 men with DM2, the BMD (g/cm2) was evaluated at the lumbar spine (L1-L4), at t...