Searchable abstracts of presentations at key conferences in endocrinology

ea0081p48 | Calcium and Bone | ECE2022

Male osteoporosis, a still overlooked and undermanaged issue: an identikit of patients seeking bone health evaluation at a tertiary academic medical centre

Vincentis Sara De , Russo Antonino , Taliani Erica , Ansaloni Anna , Domenici Daniela , Madeo Bruno , Rochira Vincenzo

Background: Male osteoporosis is undermanaged. The characteristics of men referring to health care system for bone evaluation remain partially unknown.Aim: To characterize from real-life data male patients seeking the first bone health evaluation at a tertiary academic medical center, referral for both andrological and bone diseases, over a 13-year observation period.Methods: Retrospective, cross-sectional study, including adult me...

ea0081ep793 | Pituitary and Neuroendocrinology | ECE2022

Importance of neurosurgical expertise and multidisciplinary approach in pituitary patients

Pederzoli Simone , Monzani Maria Laura , Vincentis Sara De , Madeo Bruno , Diazzi Chiara , Rochira Vincenzo

Background: Multidisciplinary approach to pituitary disease is highly recommended; it requires a close relationship between expert pituitary surgeons and endocrinologists together with several specialists (e.g. neuroradiologists) in order to provide a high-level standard of care. Although there is evidence that neurosurgeonsÂ’ expertise is a key element to achieve better outcomes, also endocrinologistsÂ’ role is fundamental but it may sometimes encounter real-life barr...

ea0063gp18 | Calcium and Bone 1 | ECE2019

Calcium to Phosphorus (Ca/P) ratio as an accurate index for the diagnosis of primary hyperparathyroidism (PHPT) and hypoparathyroidism (HypoPT)

Vincentis Sara De , Repaci Andrea , Altieri Paola , Kara Elda , Vescini Fabio , Amadori Pierluigi , Balestrieri Antonio , Rochira Vincenzo , Madeo Bruno

Background: The diagnosis of PHPT and chronic HypoPT is still challenging, mainly due to the wide spectrum of clinical and biochemical presentation and the lack of validated diagnostic index in literature. The serum Ca/P ratio has been proposed as an accurate tool to diagnose PHPT in a small sample of patients, while no data is available about its possible application for HypoPT.Aim: To validate the serum Ca/P ratio as a diagnostic index for PHPT and to ...

ea0049gp51 | Bone & Calcium Homeostasis 2 | ECE2017

Calcium to phosphorous ratio (Ca/P) as helpful index to recognize primary hyperparathyroidism, but not primary hypoparathyroidism: a big-data approach

Vincentis Sara De , Santi Daniele , Rochira Vincenzo , Setti Monica , Tagliavini Simonetta , Varani Manuela , Trenti Tommaso , Simoni Manuela , Madeo Bruno

Background: Primary hyperparathyroidism (HyperPT) and primary hypoparathyroidism (HypoPT) are often underdiagnosed. Several strategies have been investigated in the past in order to identify diagnostic parameters, although the diagnosis of both HyperPT and HypoPT remains challenging so far, especially in asymptomatic patients. Calcium (Ca) and phosphorus (P) are inversely related together, thus the Ca/P ratio could be an useful tool to define these conditions. Recently, we pro...

ea0056p745 | Neuroendocrinology | ECE2018

Serum sodium is inversely related to frailty and bone mineral density (BMD) in human immunodeficiency virus (HIV)-infected patients

Vincentis Sara De , Decaroli Maria Chiara , Diazzi Chiara , Santi Daniele , Carli Federica , Zona Stefano , Guaraldi Giovanni , Rochira Vincenzo

Background: HIV-infected patients are predisposed to an increased risk of hyponatremia. In healthy population, low sodium is associated with impaired health status and reduced BMD, but less is known about this association in HIV-infection.Aim: To investigate the relationship between serum sodium, frailty and BMD in a large cohort of HIV-infected patients.Methodology: A retrospective, observational, cohort study on adult HIV-infecte...

ea0081p30 | Calcium and Bone | ECE2022

Covid-19 lockdown negatively impacted on adherence to Denosumab therapy: incidence of non-traumatic fractures and role of telemedicine

D'Angelo Giulia , Vincentis Sara De , Domenici Daniela , Ansaloni Anna , Boselli Gisella , Russo Antonino , Taliani Erica , Rochira Vincenzo , Simoni Manuela , Madeo Bruno

Background: Adherence to anti-osteoporotic therapy is fundamental to prevent harmful consequences including fragility fractures and, in the specific case of denosumab discontinuation, of rebound fractures. Coronavirus disease (Covid-19) lockdowns have impacted on management of osteoporosis, but data about adherence to denosumab and rebound fractures during the Covid-19 pandemic are still lacking. The use of telemedicine is increasingly widespread albeit supported by little evi...

ea0049ep1166 | Male Reproduction | ECE2017

Testosterone is poorly related to erectile dysfunction in young/middle aged human immunodeficiency virus-infected men

Vincentis Sara De , Santi Daniele , Decaroli Maria Chiara , Fanelli Flaminia , Mezzullo Marco , Fazzini Alessia , Ansaloni Anna , Pagotto Uberto , Guaraldi Giovanni , Rochira Vincenzo

Background: human immunodeficiency virus (HIV)-infection is strongly associated to erectile dysfunction (ED) in men. Preliminary data suggests that ED is poorly associated with serum T in HIV+ men.Aim: To investigate in HIV-infected men the relationship between sexual function as assessed by the validated International Index of Erectile Function (IIEF-15) and T deficiency using Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS).<p class="abste...