Searchable abstracts of presentations at key conferences in endocrinology

ea0035p667 | Female reproduction | ECE2014

Increased prolactin levels cause increased MPV in women with PCOS

Yilmaz Ozgur , Calan Mehmet , Temur Muzaffer , Kume Tuncay , Yesil Pinar

Introduction: It is well known association between cardiovascular disease and PCOS. Approximately 17–43% of women with PCOS have hyperprolactinemia. Increased levels of prolactin often associated with an increased risk for thromboembolic events, but underline pathophisiological mechanism still unknown. The strong association between hyperprolactinemia and platelet aggregation is well known. Platelets play a key role in the development of atherothrombosis, a major contribu...

ea0035p370 | Diabetes (epidemiology, pathophysiology) | ECE2014

Compensatory increased irisin levels in gestational diabetes mellitus

Arkan Tugba , Calan Mehmet , Cimrin Dilek , Yesil Pinar , Oktan Mehmet Asi , Aygun Kemal , Bayraktar Firat

Context: Irisin, a newly discovered hormone, is secreted by skeletal muscles into circulation. It is proposed to regulate energy homeostasis and hold therapeutic potential in diabetes and obesity.Objective: We aimed to investigate the association of irisin and uncoupling protein 1 (UCP1) with gestational diabetes mellitus (GDM).Design and Setting: This was a cross-sectional study conducted in a university hospital.<p class="abs...

ea0041ep660 | Female Reproduction | ECE2016

Increased adipsin is associated with carotid intima media thickness and metabolic disturbances in polycystic ovary syndrome

Kocabas Gokcen Unal , Calan Ozlem Gursoy , Calan Mehmet , Senses Pinar Yesil , Ozden Ebru , Sari Kerime Rumeysa , Aktar Merve Kocar , Imamoglu Cetin , Senses Yasar Mehmet , Bozkaya Giray , Bilgir Oktay

Context: Adipsin, a protein secreted mainly from the adipose tissue, is a structural homologous of complement factor D, a rate-limiting enzyme of the alternative complement system. Growing evidence suggests that the alternative complement system plays a role both in the regulation of energy homeostasis and the atherosclerotic process. Polycystic ovary syndrome (PCOS) is an inflammatory based-metabolic disease.Objective: To ascertain whether circulating a...