Endocrine Abstracts

Objectives: Distinguishing between a healthy thyroid and autoimmune thyroid disease can sometimes be challenging. In addition to clinical and laboratory tools, as well as thyroid ultrasound, additional diagnostic tool is the elastographic assessment of thyroid tissue. With our research, we aimed to determine if we could differentiate between thyroid tissue in patients with Graves’ disease (GD) and subjects with a healthy thyroid using ultrasound shear wave elastography (S...

Introduction: Thyroid nodules can be detected by ultrasound (US) in 20–30% of unselected populations. Various non-surgical techniques such as laser and radiofrequency ablation have been developed to reduce thyroid nodule size. High-intensity focused ultrasound (HIFU) ablation is a new, non-invasive method that has been shown recently. The aim of our study was to assess the long-term efficacy and safety of US-guided HIFU treatment of benign solid thyroid nodules.<p cla...

Background: Thyroid nodule is the most common endocrine disorder with the prevalence of more than 50% in adults. Majority of nodules are small in size and can be detected only by various imaging methods. Thyroid nodules are usually benign, asymptomatic, and do not need treatment. Growing and large symptomatic thyroid nodules are usually treated with thyroidectomy. Novel minimally invasive ablation techniques can be alternative to surgery. Percutaneous laser ablation is causing...

Background: GLP-1 agonism have the potential to affect gastric emptying (GE), yet the reports for subcutaneous semaglutide, currently the most effective GLP-1 RA approved for weight management, remain inconclusive. It has been demonstrated that semaglutide either had no effect on GE or it delayed GE only within the first hour, without late phase retention. Notably, those conclusions were made by an indirect method of estimation of GE through ingestion, absorption and determina...

Objectives: Overt hyperthyroidism is reported to be associated with an increased mortality risk and an increased risk of cardiovascular (CV) complications such as an acute coronary syndrome requiring percutaneous coronary intervention, ischemic and non-ischemic stroke, atrial fibrillation and venous thromboembolism. Increased rate of acute CV events in the course of hyperthyroidism is well documented in Graves’ disease (GD) but not in subacute thyroiditis (ST). Last year ...

Introduction: The prevalence of thyroid nodules detected by ultrasound (US) is up to 50% in general population and approximately 5−10% of them is malignant. Diagnostic assessment includes laboratory tests thyroid US and thyroid scintigraphy, where suspicious nodules are characteristically cold when using99m Tc-pertechnetate as a tracer. A useful tool for US-based risk stratification of thyroid nodules is Thyroid Imaging Reporting and Data System (TIRADS). Rece...

Introduction: Radioiodine (I-131) therapy is an effective treatment for thyroid autonomy but may induce Graves’ disease (GD) but in up to 5% of patients. GD is characterised by antibodies against TSH receptor (TSHRAb). We set out to evaluate the incidence and risk factors of I-131-induced GD in patients with thyroid autonomy treated with I-131.Methods: We retrospectively reviewed patients with solitary toxic adenoma or toxic nodular goiter who were ...

Aim: In Graves’ disease (GD) the goal of radioiodine (I-131) application is the elimination of hyperthyroidism. The reported success rate 1 year after treatment is up to 90%. The aim of this retrospective study was to assess the factors influencing the early outcome 3 months after I-131 treatment of GD patients in an iodine sufficient area.Materials and Methods: We reviewed medical records of GD patients who received I-131 therapy between January 20...

Aim/Introduction: [18F]fluorocholine (FCH) positron emission tomography/computed tomography (PET/CT) has gained an important role in the preoperative diagnosis of patients with primary hyperparathyroidism (pPHP). In these patients, thyroid nodules are frequently found on preoperative ultrasound. FCH PET/CT provides a high negative predictive value to reliably rule out cancer in thyroid nodules with low uptake. However, more than half of benign thyroid nodules have b...

Objectives: Ultrasound-guided fine needle aspiration biopsy (FNAB) is a commonly performed diagnostic procedure for evaluation of thyroid nodules. The Bethesda System for Reporting Thyroid Cytopathology comprises six categories. Bethesda categories I and III present a challenge for deciding on further diagnostic and therapeutic procedures. Category I includes non-diagnostic or unsatisfactory results that may be due to both aspiration of cystic material from simple cysts or asp...