Endocrine Abstracts

A 60 year old Caucasian woman presented with a three month history of rapidly enlarging neck swelling and hoarseness of voice. Her past medical history included Hypothyroidism. Her neck ultrasound scans showed 3.5 cm left thyroid nodule with bilateral lymphadenopathy (U5). The Fine needle aspiration (FNA) revealed densely grouped variable sized irregular epithelial cells with nuclear atypia and spindle shaped fragments with focal areas of lymphocytic thyroiditis. The different...

Case history: A 26 year-old lady was admitted from clinic with severe hypertension and bilateral papilloedema. Six weeks prior to admission she had undergone resection of a massive right upper quadrant lesion that was felt to be of hepatic origin. Histological analysis of the lesion revealed it to be an adrenal phaeochromocytoma and she was thus referred to the endocrine service. Pre-operative biochemical assessment had not been performed but there was no evidence of any blood...

Background and aims: The objective of our study is to evaluate the respect of Muslim diabetics for the contraindication of fasting and the control metabolic impact of fasting during the month of Ramadan. Materials and methods: This analytical cross-sectional study was conducted during the period from Mars to June of the year 2021, within the department of endocrinology and metabolic diseases of the Military Hospital of Instruction Moham...

Background: Early diagnosis and surveillance of Graves’ Orbitopathy (GO) is essential to prevent severe, sight-threatening complications and long-term disability; therefore, it is highly desirable to identify risk factors and early predictors of severe disease. GO is clinically assessed using the Clinical Activity Score (CAS) and the EUGOGO Severity Scale (ESS), which are subjective, qualitative tests that are used to evaluate the activity and severity at the anterior orb...

Background: Syncope is common in healthy adolescents and young adults. It can happen due to hypotension secondary to orthostasis. Primary adrenal insufficiency is infrequently reported in patients presenting with syncope and dizziness caused by loss of vasopressor effect of catecholamines and volume depletion.Clinical Case: A 17-year-old boy with a past medical history of learning disability and asthma presented to our health facility with an episode of ...

Background: Hypercalcemia is a common clinical problem. Severe hypercalcemia or hypercalcemic crisis is an endocrine emergency and can be life threatening if left untreated. The condition has high mortality and requires immediate therapeutic interventions and diagnostics. A rapid rise to the calcium levels can result in the impaired function of organ systems including central nervous system. Hypercalcemia is mainly (more than 90%) caused by primary hyperparathyroidism or malig...

Introduction: We report a case of malignant hypercalcemia complicated by acute pancreatitis, in a patient whose cardiac insufficiency obliged us to use an unconventional therapeutic means: calcimimeticsCase Report: Mrs. Halima, 74 years old, had a history of arterial hypertension complicated by ischemic heart disease at the stage of heart failure. She consulted the emergency room for typical pancreatic pain, the biological workup found a lipasemia at 30 ...

Introduction: LADA (Latent Autoimmune Diabetes in Adults), is defined by the association of diabetes after 30 years, the presence of antibodies against pancreatic beta cells and the non-use of insulin therapy within 6 months of diagnosis. Graves’ disease is the first cause of hyperthyroidism associating thyrotoxicosis, goiterand exophthalmos with a prevalence 5 times higher in women.Case report: 37-year-old female patient with no notable history, la...

Context: Diabetes mellitus represents one of the most frequent metabolic comorbidities and occurs in 30% to 40% of patients with acromegaly. Patients with acromegaly develop insulin resistance due to GH excess, and in those with longstanding disease, insulin deficiency may occur. Moreover, the use of second-generation somatostatin receptor ligands (SRLs) pasireotide might contribute to the increased development in new-onset diabetes and the worsening of hyperglycemia. Manageme...

A 74-year-old male presented to hospital following an episode of brief loss of consciousness and several hours of post ictal confusion. There was no witnessed seizure activity, tongue biting, or incontinence. His past medical history included SCC right scalp, TIA and primary hypothyroidism. He had been commenced on Cemiplimab (immunotherapy) for metastatic SCC seven months before. On assessment, he appeared well and general examination including neurological examination was no...