Endocrine Abstracts

IntroductionThe only currently available treatment of coeliac disease is a gluten-free diet (GFD). It improves outcomes, and reduces health-care costs. However, adhering to a gluten-free diet is difficult for many people. The aim of this study is to evaluate the diet adherence in real life and his impact on disease evolution.Patients and methodsThis is a descriptive transversal study carried out over a period...

IntroductionCeliac disease is an autoimmune enteropathy secondary to gluten intolerance developing in genetically predisposed patients. The atypical presentation is the most common form of the disease. The aim of this work is to report the various extradigestive manifestations associated with celiac disease.Patients and methodsThis is a descriptive transversal study carried out over a period of 10 years. All ...

IntroductionThe occurrence of thromboembolic events in celiac disease has been reported in the literature, especially in adults. The objective of our study is to determine the prevalence and clinical characteristics of thrombosis in celiac disease and to clarify the role of thrombophilic factors.Patients and methodsThis is a retrospective series of four observations of thrombosis among a cohort of 41 patients...

Introduction: The diagnosis of Cushing’s syndrome is frequently invoked by the presence of clincal signs of hypercatabolism. It actually may be associated with a variety of dermatological manifestations which can be atypical. Here, we report the case of a patient having vulvar warts co-occuring with Cushing’s syndrome.Observation: We present the case of a 31-year-old patient presenting with typical signs of Cushing’s syndrome: Facial eryth...

Introduction: Follicular thyroid carcinoma typically spreads through the hematogenous route, causing distant metastases, with bone and lung being the most frequent sites, while metastases to the liver and skin are less common. We report a case of reassessing the diagnosis of follicular thyroid carcinoma due to the identification of flesh-colored skin nodules, later confirmed as cutaneous metastases.Case presentation: An otherwise healthy 60-year-old man ...

Introduction: Diabetes is a chronic, progressive disease characterized by elevated levels of blood glucose. In type 1 diabetes, some patients experience a “honeymoon period” shortly after diagnosis, wherein insulin needs decrease significantly and a few studies have demonstrated that drug-free glycemic control can be achieved in type 2 diabetes. We describe 2 unusual cases of endogenous hyperinsulinism and diabetes remission.Case presentation 1...

Introduction: Obesity exposes to multiple complications, including cardiovascular and metabolic ones. It can also cause respiratory problems, which are still insufficiently researched. The objective of this study was to detect respiratory abnormalities in a group of obese people followed in an obesity unit.Methods: This was a descriptive and analytical cross-sectional study of 100 obese patients consulting at the human obesity research unit of the Nation...

Introduction: The global pandemic spread of SARScov2 has led to a heavy medical and socio-economic toll since December 2019. Patients suffering from chronic diseases were particularly affected during the lockdown period due to difficulties in accessing care. The aim of our study was to evaluate the impact of the 2-month lockdown introduced in Tunisia in March 2020 on diabetic patients’ glycemic control.Materials and methodsRetrospective study involving 54 diabetic patient...

Introduction: Diabetes is the cause of ophthalmological complications that are all the more severe when the balance of diabetes is precarious. Among the non-retinal ocular targets of diabetes is damage to the optic nerve. The diagnosis of diabetic mononeuritis should only be made after excluding other causes of neuropathy.Observation: We report the case of a patient referred to our service for equilibration of diabetes. This is a 59-year-old patient, typ...

Obesity is a major public health problem. It is a privileged provider of a constellation of metabolic abnormalities, particularly lipids, increasing the risk of morbidity and mortality and hampering the quality of life of the obese.Material and methods: We conducted a prospective study on 100 obese patients recruited at the Human Obesity Research Unit at the National Institute of Nutrition in Tunis. Our patients benefited from an assay of fasting insulin...