Endocrine Abstracts

Introduction: Cushing’s disease (CD) is associated with metabolic and cardiovascular comorbidities that can be incompletely resolved after disease remission. Our objective was to evaluate the metabolic and cardiovascular status of patients with MC in remissionPatients and methods: We performed a retrospective study including 15 CD patients cured by pituitary surgery. Patient’s medical records were reviewed and information regarding blood pressu...

Introduction: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders that result from the deficiency of one of several enzymes involved in the steroidogenic pathway for cortisol biosynthesis. The most common cause of CAH, accounting for 90% of cases, is 21-hydroxylase deficiency. The symptoms of disease very depending on the nature and severity of the enzyme deficiency as well as the sex of the individual. Non-classical CAH is generally late onset. Ho...

Introduction: The objective of our study was to study the evolution of the weight of a population of diabetic patients previously educated and having fasted the month of Ramadan.Methods: This is a prospective study that involved 140 patients who wish to fast the month of Ramadan (2016) and who have presented themselves at consultations dedicated to preparing diabetic patients wishing to fast, organized at the National Institute of Nutrition of Tunis (Dep...

Introduction: Several studies have been conducted to study the effect of fasting on the clinical and metabolic parameters of patients with multiple cardiovascular risk factors, particularly diabetes, hypertension, and dyslipidemia. Our aim was to study the effect of Ramadan fasting on the clinical and metabolic parameters of a previously educated population of diabetic, hypertensive and dyslipidemic patients.Methods: This is a prospective study that invo...

Background: Physical activity is associated with several health benefits, including lower obesity and diabetes risk. Many different factors influenced physical activity patterns of adolescents in a complex interactive way. The aim of this study was to assess association between physical inactivity and socioeconomic factors and lifestyle among Tunisian adolescents.Methods: A cross-sectional study was carried out in Sousse, Tunisia during the school year 2...

Introduction: Metabolic syndrome (MS) is a high-risk vascular risk situation. The aim of this study was to assess the prevalence of MS in a population of diabetic patients.Methods: It was a descriptive study conducted from March to September 2017 on 122 diabetics hospitalized at the National Institute of Nutrition. The SM is defined according to the IDF 2005 criteria. All patients underwent careful questioning, a complete clinical examination with anthro...

Introduction: RaisedCRP is observed in obesity, metabolic syndrome and type 2 diabetes in the absence of any inflammatory or infectious disease. Indeed, it may constitute a mark of cardiovascular risk and macro and micro-vascular complications. The objective of our study is to assess the association between raised ultra-sensitive CRP and macro-vascular and micro-vascular complications in a group ofpatients with type 2 diabetes (T2DM).Materials and method...

Introduction: Sarcoidosis affects both the central and peripheral nervous system in 5–16% of patients. In most cases, such involvement occurs within a multi-systemic disease. Endocrine manifestations of neurosarcoidosis can be expressed by hypothalamic dysfunction, diabetes insipidus, hypopituitarism, hyperprolactinemia, in isolated fashion or variedly combined.Herein, we report a case of neurosarcoidosis revealed by an obstructive hydrocephalus, a...

Background: Severe hypercalcemia, defined as a serum calcium concentration ≥ 3.5 mmol/l or > 3 mmol/l associated with symptoms and signs of acute calcium intoxication, is a rare but a potentially life threatening condition. The aim of this study was to assess clinical, paraclinical, etiological and therapeutic features of severe hypercalcemia and to determine its outcome.Methods: It was a retrospective, descriptive and comparative study conduct...

Aim: The aim of our study was to describe the lipid profile of Tunisian women after pregnancy with gestational diabetes mellitus (GDM) and to analyze the influence of maternal age, insulin requirement and postpartum glycemic status on lipoproteins changes after pregnancy.Methods: We conducted a cross-sectional study among pregnant women who were referred to the national institute of nutrition for management of GDM. The lipid profile included total choles...