Endocrine Abstracts

Background: There are no definite recommendations on the optimal dosage of initiating adjuvant radioactive iodine (RAI) therapy for intermediate-risk differentiated thyroid cancer (DTC) patients in current relevant guideline. This study aimed to investigate the response of intermediate-risk DTC patients with a low (3.7GBq) or high RAI dose (5.55GBq).Methods: Propensity score matching was performed to control for baseline characteristics. A total of 476 p...

Objective: To explore the association between body mass index (BMI) and plasma glucose level with pathological features and clinical outcomes of differentiated thyroid cancer (DTC).Methods: Clinical data of 1264 consecutive DTC patients treated with total thyroidectomy and enrolled at the time of the first 131I treatment from April 2016 to July 2020. The clinicopathological findings were compared in the groups were categorized according to BMI...

Background: Growing evidence suggests a link between sugar-sweetened beverages (SSBs) and metabolic disorders. We investigated the effect of SSBs that are commonly consumed by adolescents on glucose metabolism and fatty liver.Methods: We treated 7-week old male C57BL/6 mice with water (control) or either of SSBs: carbonated soda (Coca-Cola®), sweetened milk coffee (Maxwell®), or chocolate-added cocoa (Choco-Latte&#174...

Aims: This population-based cross-sectional study aimed to investigate the recent trends in the prevalence and treatment of gestational diabetes mellitus (GDM) in a nationally representative sample of Korean patients. We also investigated trends of annual prevalence rate of pregnancy-induced hypertension (PIH) and cesarean section (C-section) in patients with GDM.Methods: We used data from the Health Insurance Review and Assessment-National Patient Sampl...

Backgrounds: Cerebral aneurysms are a common disease that affects 1–5% of general populations, with an annual rupture risk of 0–1%. Smoking, high blood pressure, diabetes and aging have been considered as risk factors for cerebral aneurysms, but there were few epidemic studies. In this study, we evaluated the risk effect of diabetes on cerebral aneurysm in Korean population.Methods: We used data from participants who underwent brain MRA and l...

Aims/Introduction: It is thought that adipocytokines contribute to the increased riskof vascular complications in type 2 diabetes (T2DM). However, some data indicate that adipocytokines may protect against cardiovascular disease. The net effects of adipocytokines on vascular pathology are complex and not completely understood. Although previous our cross-sectional studies showed that adipocytokines such as adiponectin, leptin, and TNF-alfa were associated with vascular complic...

Aim: To evaluate the relationship between insulin resistance and cutaneous vasomotor responses (endothelial-dependent vasodilatation and peripheral sympathetic failure: noradrenergic control of smooth muscle cells – vasoconstriction and neuropeptides induced vasodilatation) in patients with metabolic syndrome (MS).Methods and subjects: Patients with insulin resistance and MS (defined according to ‘The 2005 IDF definition of the metabolic syndro...

Objective: Although the importance of islet α-cell dysfunction in the pathogenesis of type 2 diabetes has been reappraised, data on whether increase or decrease of glucagon relative to insulin is related with glucose metabolism parameters or metabolic diseases such as nonalcoholic fatty liver disease(NAFLD) in clinical settings are very limited. Therefore, we investigated the association between glucagon-to-insulin ratio(G/I ratio) and presence of NAFLD and metabolic para...

The advent of Web-based patient management technologies, including Web-based messaging, video conferencing, remote monitoring of vital signs, and Web-based educational programs, has resulted in the recognition that telemedicine may benefit diabetic patients with limited access to healthcare providers and/or a high burden of disease. In this regard, 24-week prospective multi-center randomized controlled trial involved 338 adult patients with type 2 diabetes at four university h...

Objective: To determine whether the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS) 4 nodules can be subcategorized by ultrasonography (US)-based stratification of malignancy risk, and to evaluate the diagnostic performance of the modified biopsy criterion based on the subcategorization of the K-TIRADS 4 category in a multicenter cohort.Materials and Methods: A total of 1,541 K-TIRADS 4 nodules (≥ 1 cm) with final diagnoses were include...