Endocrine Abstracts

Background: Non-alcoholic fatty liver disease (NAFLD) is metabolic disorder of the liver that is associated with type 2 diabetes.The relationship between NAFLD and diabetic neuropathy was still poorly understood. This study aimed to investigate whether the NAFLD is associated with the autonomic neuropathy parameters in patients with type 2 diabetes.Methods: A total of 174 patients with type 2 diabetes were included in this study. Patients were divided in...

Objective: Dipeptidyl peptidase (DPP)-4 is highly abundant in the kidney. In various chronic inflammatory diseases, soluble DPP-4 activity is used as a marker for diabetes, coronary artery disease and cancer. This study examined the association between serum soluble DPP-4 levels and renal function or cardiovascular risk in patients with type 2 diabetes mellitus.Research design and methods: Soluble DPP-4 activities were measured retrospectively in a total...

Objective: Dapagliflozin, sodium-glucose cotransporter-2 (SGLT-2) inhibitor, reduces hyperglycemia and body weight by inhibiting renal glucose reabsorption. However, only a few studies have shown the glycemic efficacy on a combination of dapagliflozin in type 2 diabetic patients in Korean. We evaluated the efficacy and safety of glucose control on a combination of dapagliflozin in people with type 2 diabetes in Korea.Methods: This is a retrospective, obs...

Background/objectives: This study aimed to investigate associations between self-reported sleep duration and general and abdominal obesity in Korean adults stratified according to sex and age.Subjects/methods: Data from 41,805 adults, 18–110 years of age, collected by the Korean National Health and Nutrition Examination Survey (KNHANES) in 2007 and 2015, were included. Obesity was defined as body mass index (BMI) ≥25 kg/m2, and abdo...

Thyroid nodules were frequently incidentally discovered during radiologic studies of chest or neck. We investigated the prevalence and clinical importance of thyroid incidentaloma during carotid artery ultrasonography in patients with diabetes. We retrospectively reviewed the data of enrolling all diabetic patients who were performed carotid artery ultrasonography at the Diabetes Center of Wonju Severance Christian Hospital from January to December 2013. Chart reviews of all e...

Objectives: The aim of this study was to evaluate the diagnostic performance of biopsy criteria in four society ultrasonography (US)-based risk stratification systems (RSSs) or thyroid imaging reporting and data system (TIRADS) including the 2021 Korean (K)-TIRADS for thyroid nodules.Methods: Ovid-Medline, EMBASE, Cochrane, and KoreaMed databases were searched and other eligible articles by manual search were included to identify original articles invest...

Background: We evaluated the impact of the multifocality on post-lobectomy recurrence in patients with differentiated thyroid cancer (DTC).Methods: We analyzed 1,684 patients with DTC who underwent thyroid lobectomy from 2008 to 2015 using logistic regression models to calculate the relative risk on post-lobectomy recurrence.Results: Tumor diameter increased from 4.9 mm to 8.1 mm and the proportion of extrathyroidal extension (ETE)...

Aim: There is little real-world evidence comparing the effectiveness of real-time continuous glucose monitoring (rtCGM) and intermittently-scanned continuous glucose monitoring (isCGM) in glycemic control, with a large population and long-term follow-up. This study aimed to compare the association of rtCGM and isCGM with glycemic control in individuals with type 1 diabetes (T1D) in a real-world setting.Methods: From the Korean National Health Insurance S...

Background: Differentiated thyroid carcinoma is the most common endocrinological malignancy with an increasing incidence over the last 30 years. It is the fifth most common cancer among the young population (15–39 years), with women being more frequently affected. Surgical removal of the tumour is the standard treatment method. In indicated cases, total thyroidectomy with subsequent adjuvant radioiodine administration is performed, despite international trends towards les...

Background: Gas-forming pyogenic liver abscess is an uncommon, life-threatening infection that is usually found in poorly-controlled diabetic patients. Here, we experienced a case of gas-forming pyogenic liver abscess in diabetes caused by Klebsiella pneumoniae.Clinical case: A 77-year-old man with 25-year history of diabetes was admitted due to fever for 2 days. On the physical examination, right upper quadrant tenderness of the abdomen was present. Ini...