Searchable abstracts of presentations at key conferences in endocrinology

ea0026p653 | Clinical case reports | ECE2011

Maltose interference in the determination of blood glucose levels by test strips based on glucose dehydrogenase-PQQ method: a case report

Belo S , Rodrigues P , Alves M , Neves C , Magalhaes A , Carvalho D

Background: The different systems for monitoring capillary blood glucose levels may suffer interference from various substances.Case report: Male patient, 48 years old, with history of hypertension, dyslipidemia and previous smoking. He presented also type 1 diabetes mellitus, with 37 years of progress, with diabetic retinopathy, kidney failure, in peritoneal dialysis since 2009, and ischemic heart disease (myocardial infarction in 2005). He was treated ...

ea0099p377 | Thyroid | ECE2024

Characterization of a series of 661 papillary throid microcarcinoma with excellent response to treatment

Rodrigues Elisabete , Silva Paulo , Magalhaes Joao , Pinto Mafalda , Pimenta Tiago , Sobrinho-Simoes Manuel , Soares Paula

Introduction: The management of small size (≤ 1 cm) papillary thyroid carcinoma, also known as papillary thyroid microcarcinoma (PTMC) is a debated topic as it includes tumors with a wide range of biological characteristics and behavior.Objectives: To describe prevalence, clinical and histological characteristics of PTMC with excellent response to treatment after a median follow up of 9.85±6.21 years.Methods: We did a re...

ea0041ep282 | Clinical case reports - Pituitary/Adrenal | ECE2016

Cyclic Cushing’s syndrome – a diagnostic challenge

Magalhaes Daniela , Bettencourt-Silva Rita , Queiros Joana , Freitas Paula , Vinha Eduardo , Pignatelli Duarte , Pereira Josue , Carvalho Davide

Introduction: The diagnosis of Cushing’s syndrome is often challenging considering that none of the used laboratory tests has an ideal diagnostic accuracy. The complexity of the diagnosis increases in cyclic disorder, which is characterized by repeated episodes of cortisol excess followed by periods of normal cortisol secretion.Case report: A 32-year-old woman with history of arterial hypertension and obesity presented with weight gain, hirsutism, a...

ea0041ep634 | Endocrine tumours and neoplasia | ECE2016

Hypoglycaemia unawareness – a challenge in the management of a Von Hippel-Lindau patient

Bettencourt-Silva Rita , Souteiro Pedro , Magalhaes Daniela , Oliveira Joana , Bessa de Melo Renato , Costa Maia Jose , Carvalho Davide , Queiros Joana

Background: The key physiologic defences against hypoglycaemia are the decrease in insulin and the increased secretion of glucose counterregulatory hormones, namely glucagon and epinephrine. The absence of warning signs of impending neuroglycopenia is known as hypoglycaemic unawareness.Case report: Male, 26 year-old, without relevant medical history and with normal body mass index, presented with hypertension, palpitations and diaphoresis. Clinical suspi...

ea0026p610 | Clinical case reports | ECE2011

Cholestatic jaundice methimazole-induced or secondary to heart failure?

Souto S B , Rodrigues P , Belo S , Nogueira C , Magalhaes A , Castedo J L , Carvalho-Braga D , Carvalho D

Methimazole-induced cholestatic jaundice is a rare adverse effect, dose-dependent, occurring within the first 3 months of use, usually reversible within 3 months after discontinuing drug therapy.Case report: Woman, 64 years, history of hyperthiroidism since August 2009, under therapy with methimazole 5 mg/day. The patient was referred to endocrinology department in March 2010, with history of heart failure, atrial fibrillation, type 2 diabetes mellitus, ...

ea0026p613 | Clinical case reports | ECE2011

Diabetes insipidus in the context of sarcoidosis: a case report

Mesquita J , Rodrigues P , Belo S , Sousa A , Varela A , Magalhaes A , Castedo J L , Melo N , Mota Patricia , Carvalho Davide

Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology with a prevalence of 10–20/100 000 individuals and affects mainly young adults. Neurological involvement occurs in about 5% of the cases and it can affect the hypothalamic–pituitary axis. In this case, the most common endocrine manifestations are hyperprolactinemia and diabetes insipidus.Case report: A 44-year-old male patient complaining of not feeling well and d...

ea0020p281 | Clinical case reports and clinical reports | ECE2009

Amiodarone-induced thyrotoxicosis – case report

Souto Selma B , Matos Maria J , Freitas Paula , Queiros Joana , Magalhaes Angela , Carvalho-Braga Daniel , Medina Jose Luis

Introduction: Amiodarone-induced thyrotoxicosis(AIT) is a condition fraught with difficulties from the diagnostic and therapeutic standpoints. It can be developed precociously or years after the beginning amiodarone uptake and after its suspension. AIT is subdivided in three different forms. Type 1 is developed in subjects with underlying thyroid disease, being caused by an exacerbation by iodine load of thyroid autonomous function. Type 2 is a form of destructive thyroiditis ...

ea0090rc1.4 | Rapid Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2023

Angiotensin-converting enzyme in type II diabetes: effects of combined training on cardiovascular components and blood components

Matos Andreia , Gil Angela , Alonso Isanete , P. Magalhaes Joao , Santos Ana Carolina , Ribeiro Rogerio , F. Raposo Joao , B. Sardinha Luis , Bicho Manuel

Objectives: The angiotensin-converting enzyme (ACE1) gene is one of the most studied genes in the pathogenesis of type II diabetes (T2DM) and cardiovascular disease. However, in the context of exerciSemodels in T2DM, they are not yet fully understood. We intended to characterize the genetic profile of individuals with T2DM from an inter-individual point of view using prognostic markers and cardiovascular risk. On the other hand, relate it with the profile obtained wit...

ea0049ep140 | Clinical case reports - Pituitary/Adrenal | ECE2017

Virilization – a non-negligible manifestation of an adrenal tumor

Magalhaes Daniela , Vinha Eduardo , Neves Joao Sergio , Souteiro Pedro , Neves Celestino , Freitas Paula , Maia Jose Costa , Rios Elisabete , Fernandes Ana Catarina , Rodrigues Elisabete , Carvalho Davide

Introduction: Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy with a poor prognosis. Hormone-secreting ACC appear with manifestations of virilization, feminization or Cushing syndrome.Case Report: A 63-year-old woman with no pathological history of relief was referred to Endocrinology evaluation with an history of deepening of the voice since 1-year ago, as well as hair loss and facial and abdominal hirsutism with 6-month evo...

ea0049ep477 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Lack of postpartum reclassification test in gestational diabetes – factors conditioning loss of follow-up

Bettencourt-Silva Rita , Souteiro Pedro , Magalhaes Daniela , Belo Sandra , Oliveira Ana , Carvalho Davide , Queiros Joana , Queiros Diabetes and Pregnancy Study Group Portuguese Society of Diabetology

Introduction: Gestational diabetes mellitus (GDM) is a risk factor for maternal-fetal complications and development of diabetes or intermediate hyperglycemia after pregnancy. The follow-up should be done by a multidisciplinary team. After delivery, all women diagnosed with GDM should undergo an oral glucose tolerance test (OGTT) for reclassificationAim: To evaluate the non-adherence factors to reclassification OGTT after GDM.Method...